AU7226798A - 9-oxime erythromycin derivatives - Google Patents

9-oxime erythromycin derivatives Download PDF

Info

Publication number
AU7226798A
AU7226798A AU72267/98A AU7226798A AU7226798A AU 7226798 A AU7226798 A AU 7226798A AU 72267/98 A AU72267/98 A AU 72267/98A AU 7226798 A AU7226798 A AU 7226798A AU 7226798 A AU7226798 A AU 7226798A
Authority
AU
Australia
Prior art keywords
carbamate
deoxo
deoxy
desosaminyl
hydrazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72267/98A
Other languages
English (en)
Inventor
Yong-Jin Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of AU7226798A publication Critical patent/AU7226798A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU72267/98A 1997-06-11 1998-05-15 9-oxime erythromycin derivatives Abandoned AU7226798A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4934997P 1997-06-11 1997-06-11
US60049349 1997-06-11
PCT/IB1998/000741 WO1998056800A1 (en) 1997-06-11 1998-05-15 9-oxime erythromycin derivatives

Publications (1)

Publication Number Publication Date
AU7226798A true AU7226798A (en) 1998-12-30

Family

ID=21959341

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72267/98A Abandoned AU7226798A (en) 1997-06-11 1998-05-15 9-oxime erythromycin derivatives

Country Status (31)

Country Link
EP (1) EP0988308A1 (id)
JP (1) JP2000513026A (id)
KR (1) KR20010013660A (id)
CN (1) CN1259135A (id)
AP (1) AP9801253A0 (id)
AR (1) AR012244A1 (id)
AU (1) AU7226798A (id)
BG (1) BG103947A (id)
BR (1) BR9810021A (id)
CA (1) CA2293335A1 (id)
CO (1) CO4940506A1 (id)
CZ (1) CZ9904388A3 (id)
EA (1) EA199901016A1 (id)
GT (1) GT199800074A (id)
HN (1) HN1998000073A (id)
HR (1) HRP980316A2 (id)
HU (1) HUP0002252A3 (id)
ID (1) ID24529A (id)
IL (1) IL132767A0 (id)
IS (1) IS5251A (id)
MA (1) MA26505A1 (id)
NO (1) NO996108L (id)
OA (1) OA11225A (id)
PA (1) PA8451801A1 (id)
PE (1) PE79899A1 (id)
PL (1) PL337606A1 (id)
TN (1) TNSN98083A1 (id)
TR (1) TR199902995T2 (id)
TW (1) TW448174B (id)
WO (1) WO1998056800A1 (id)
ZA (1) ZA985018B (id)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
WO2000017218A1 (en) 1998-09-22 2000-03-30 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en) 1998-12-02 2001-07-10 Pfizer Inc. Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) * 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
KR100710605B1 (ko) * 1999-04-16 2007-04-24 코산 바이오사이언시즈, 인코포레이티드 매크롤라이드 항감염제
JP2003500414A (ja) 1999-05-24 2003-01-07 ファイザー・プロダクツ・インク １３−メチルエリスロマイシン誘導体
MXPA01012661A (es) * 1999-06-07 2002-07-22 Abbott Lab Derivados de 6-o-carbamato quetolida.
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1439186A3 (en) * 1999-12-29 2004-11-03 Pfizer Products Inc. Intermediates for novel antibacterial and prokinetic macrolides
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en) 2000-07-05 2002-06-11 Pfizer Inc. Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
US7601695B2 (en) * 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
WO2009055557A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
CN102146085B (zh) * 2010-02-09 2014-03-26 北京理工大学 一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
WO2011119604A1 (en) 2010-03-22 2011-09-29 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
CA2868262A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
CA2907085A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
OA11225A (en) 2003-07-17
PA8451801A1 (es) 2000-05-24
GT199800074A (es) 1999-11-27
TNSN98083A1 (fr) 2005-03-15
EA199901016A1 (ru) 2000-06-26
ID24529A (id) 2000-07-20
EP0988308A1 (en) 2000-03-29
CN1259135A (zh) 2000-07-05
AP9801253A0 (en) 1999-12-04
AR012244A1 (es) 2000-09-27
CA2293335A1 (en) 1998-12-17
ZA985018B (en) 1999-12-10
CZ9904388A3 (cs) 2002-10-16
BR9810021A (pt) 2000-09-19
NO996108L (no) 2000-02-10
TR199902995T2 (xx) 2000-02-21
PL337606A1 (en) 2000-08-28
CO4940506A1 (es) 2000-07-24
TW448174B (en) 2001-08-01
IL132767A0 (en) 2001-03-19
IS5251A (is) 1999-11-16
HUP0002252A3 (en) 2002-01-28
HUP0002252A2 (hu) 2000-12-28
KR20010013660A (ko) 2001-02-26
HN1998000073A (es) 1999-01-08
BG103947A (en) 2000-07-31
PE79899A1 (es) 1999-08-25
NO996108D0 (no) 1999-12-10
WO1998056800A1 (en) 1998-12-17
MA26505A1 (fr) 2004-12-20
HRP980316A2 (en) 1999-04-30
JP2000513026A (ja) 2000-10-03

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted