AU713616B2 - Cellular and serum protein anchors for diagnostic imaging - Google Patents

Cellular and serum protein anchors for diagnostic imaging Download PDF

Info

Publication number
AU713616B2
AU713616B2 AU15277/97A AU1527797A AU713616B2 AU 713616 B2 AU713616 B2 AU 713616B2 AU 15277/97 A AU15277/97 A AU 15277/97A AU 1527797 A AU1527797 A AU 1527797A AU 713616 B2 AU713616 B2 AU 713616B2
Authority
AU
Australia
Prior art keywords
vascular
functional group
binding member
reactive functional
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU15277/97A
Other languages
English (en)
Other versions
AU1527797A (en
Inventor
Alan M. Ezrin
Alexander Krantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ConjuChem Inc
Original Assignee
ConjuChem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ConjuChem Inc filed Critical ConjuChem Inc
Publication of AU1527797A publication Critical patent/AU1527797A/en
Assigned to CONJUCHEM, INC. reassignment CONJUCHEM, INC. Amend patent request/document other than specification (104) Assignors: REDCELL CANADA, INC.
Application granted granted Critical
Publication of AU713616B2 publication Critical patent/AU713616B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU15277/97A 1996-01-12 1997-01-07 Cellular and serum protein anchors for diagnostic imaging Ceased AU713616B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58891296A 1996-01-12 1996-01-12
US08/588912 1996-01-12
PCT/US1997/000176 WO1997025074A2 (fr) 1996-01-12 1997-01-07 Ancres de proteines seriques et cellulaires destinees a l'imagerie diagnostique

Publications (2)

Publication Number Publication Date
AU1527797A AU1527797A (en) 1997-08-01
AU713616B2 true AU713616B2 (en) 1999-12-09

Family

ID=24355824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15277/97A Ceased AU713616B2 (en) 1996-01-12 1997-01-07 Cellular and serum protein anchors for diagnostic imaging

Country Status (5)

Country Link
EP (1) EP0814850A1 (fr)
JP (1) JP2000504316A (fr)
AU (1) AU713616B2 (fr)
CA (1) CA2215152A1 (fr)
WO (1) WO1997025074A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1519699A (en) * 1997-11-07 1999-05-31 Conjuchem, Inc. Affinity markers for human serum albumin
CA2330611A1 (fr) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Molecules bifonctionnelles et therapies basees sur celles-ci
CA2501421A1 (fr) 1999-05-17 2000-11-23 Conjuchem Inc. Exendin-4 a longue duree d'action
US7601691B2 (en) 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US7220552B1 (en) 1999-11-19 2007-05-22 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and their use in the disruption of protein-protein interactions
AU2044001A (en) 1999-11-19 2001-05-30 Board Of Trustees Of The Leland Stanford Junior University Targeted bifunctional molecules and therapies based thereon
US6887842B1 (en) 1999-11-19 2005-05-03 The Board Of Trustees Of The Leland Stanford Junior University Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
US7112567B2 (en) 2001-02-16 2006-09-26 Conjuchem Inc. Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders
US7927579B2 (en) 2003-01-17 2011-04-19 Advanced Proteome Therapeutics, Inc Tandem analyses of noncovalently driven effectors for modulatory mapping of activities of protein sites

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2390408A1 (fr) * 1977-05-11 1978-12-08 Philips France Procede de marquage par un isotope radioactif d'un sel hydrosoluble d'oxine, ou de ses derives halogenes ou sulfones, produits ainsi marques, procede de marquage des elements figures du sang, et medicaments ainsi obtenus
FR2486657A1 (fr) * 1980-07-09 1982-01-15 Pasteur Institut Procede de detection et de dosage d'une substance biologique par erythroadsorption
FR2644059B1 (fr) * 1989-03-08 1994-03-04 Fabre Medicament Pierre Compositions aerosols destinees a l'imagerie, au diagnostic et a la therapie ciblee de foyers inflammatoires et tumoraux
FR2660864A1 (fr) * 1990-04-13 1991-10-18 Guerbet Sa Composition de contraste, procede de preparation de cette composition et application a l'imagerie.
FR2698272B1 (fr) * 1992-11-20 1994-12-30 Cis Bio Int Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Also Published As

Publication number Publication date
WO1997025074A2 (fr) 1997-07-17
JP2000504316A (ja) 2000-04-11
WO1997025074A3 (fr) 1997-11-13
AU1527797A (en) 1997-08-01
CA2215152A1 (fr) 1997-07-17
EP0814850A1 (fr) 1998-01-07

Similar Documents

Publication Publication Date Title
KR100211394B1 (ko) 심장혈관 병변의 검출방법
US5851527A (en) Method for antibody targeting of therapeutic agents
AU646658B2 (en) Chimeric antibody for detection and therapy of infectious and inflammatory lesions
EP0793506B1 (fr) Proteine serique et cellulaire d'ancrage et conjugues
AU649952B2 (en) Method for antibody targeting of diagnostic or therapeutic agents
JP4948742B2 (ja) ペプチド系化合物
CA1260827A (fr) Complexes anticorps - ions metalliques
US5326778A (en) Conjugates of biotin and deferoxamine for radioimmunoimaging and radioimmunotherapy
JPH05505606A (ja) 毛管障壁を透過する抗体の増加した移動を達成する投与剤
WO1999000150A2 (fr) Ciblage d'un medicament radiopharmaceutique peptidique utilisant in vivo la barriere hemato-encephalique d'un primate et un anticorps monoclonal dirige contre le recepteur humain de l'insuline
JPH03500419A (ja) 多特異抗白血球結合体及び哺乳動物用非経口的注射剤
EP0236619A1 (fr) Polypeptide, pour utilisation dans le ciblage et l'identification des lymphocytes-T activés
AU713616B2 (en) Cellular and serum protein anchors for diagnostic imaging
US6638508B2 (en) Modified avidin-type molecules as targeting agents for the liver and cells of the reticuloendothelial system
JP3074160B2 (ja) 悪性腫瘍用画像化剤
US5628979A (en) Reagent for tumor imaging and therapy
US20020018751A1 (en) Cellular and serum protein anchors for diagnostic imaging
Yoo et al. N-acetylgalactosamino dendrons as clearing agents to enhance liver targeting of model antibody-fusion protein
US6210655B1 (en) Site-specific 13C-enriched reagents for diagnostic medicine by magnetic resonance imaging
CN1638807B (zh) 在预靶向的放射免疫治疗中有效增加放射性生物素浓度的抗生物素蛋白二聚体
Kijlstra et al. Clearance and glomerular localization of preformed DNP anti‐DNP immune complexes
JP2006525289A (ja) ペプチド誘導体を用いたinvivo画像化方法
CN100591361C (zh) 包含载体、靶向部分和造影剂的医学成像用缀合物
CA2005162A1 (fr) Methode de ciblage par anticorps des agents de diagnostic ou des agents therapeutiques
WO1997022879A1 (fr) Molecules modifiees du type avidine utilisees comme agents de ciblage pour le foie et les cellules du systeme reticulo-endothelial

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired