AU686690B2 - Novel taxoids, their preparation and pharmaceutical compositions containing them - Google Patents

Novel taxoids, their preparation and pharmaceutical compositions containing them Download PDF

Info

Publication number
AU686690B2
AU686690B2 AU81470/94A AU8147094A AU686690B2 AU 686690 B2 AU686690 B2 AU 686690B2 AU 81470/94 A AU81470/94 A AU 81470/94A AU 8147094 A AU8147094 A AU 8147094A AU 686690 B2 AU686690 B2 AU 686690B2
Authority
AU
Australia
Prior art keywords
radicals
carbon atoms
radical
product
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU81470/94A
Other languages
English (en)
Other versions
AU8147094A (en
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Jean-Pierre Pulicani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of AU8147094A publication Critical patent/AU8147094A/en
Application granted granted Critical
Publication of AU686690B2 publication Critical patent/AU686690B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU81470/94A 1993-11-08 1994-11-07 Novel taxoids, their preparation and pharmaceutical compositions containing them Ceased AU686690B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9313233 1993-11-08
FR9313233A FR2712288B1 (fr) 1993-11-08 1993-11-08 Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1994/001283 WO1995013271A1 (fr) 1993-11-08 1994-11-07 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
AU8147094A AU8147094A (en) 1995-05-29
AU686690B2 true AU686690B2 (en) 1998-02-12

Family

ID=9452585

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81470/94A Ceased AU686690B2 (en) 1993-11-08 1994-11-07 Novel taxoids, their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
EP (1) EP0728131A1 (fi)
JP (1) JPH09504801A (fi)
CN (1) CN1134700A (fi)
AU (1) AU686690B2 (fi)
CA (1) CA2175384A1 (fi)
CZ (1) CZ133696A3 (fi)
FI (1) FI961938A0 (fi)
FR (1) FR2712288B1 (fi)
HU (1) HUT75063A (fi)
PL (1) PL314234A1 (fi)
SK (1) SK57496A3 (fi)
WO (1) WO1995013271A1 (fi)
ZA (1) ZA948789B (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10098865B2 (en) 2010-12-22 2018-10-16 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
CA2162759A1 (en) * 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
EP0914116B1 (en) * 1996-05-22 2000-10-11 Protarga Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US20100160653A1 (en) * 2006-03-21 2010-06-24 Dr. Reddy's Laboratories Ltd. Docetaxel polymorphs and processes
EP2331140B1 (en) 2008-08-11 2018-07-04 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
CN111748825B (zh) * 2019-03-28 2021-09-07 万华化学集团股份有限公司 一种成对电极反应制备ε-己内酯的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10098865B2 (en) 2010-12-22 2018-10-16 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds

Also Published As

Publication number Publication date
HU9601219D0 (en) 1996-07-29
SK57496A3 (en) 1996-10-02
FI961938A (fi) 1996-05-07
JPH09504801A (ja) 1997-05-13
CZ133696A3 (en) 1996-08-14
CA2175384A1 (fr) 1995-05-18
FR2712288A1 (fr) 1995-05-19
FI961938A0 (fi) 1996-05-07
ZA948789B (en) 1995-07-12
CN1134700A (zh) 1996-10-30
PL314234A1 (en) 1996-09-02
FR2712288B1 (fr) 1996-01-05
AU8147094A (en) 1995-05-29
EP0728131A1 (fr) 1996-08-28
HUT75063A (en) 1997-03-28
WO1995013271A1 (fr) 1995-05-18

Similar Documents

Publication Publication Date Title
US5847170A (en) Taxoids, their preparation and pharmaceutical compositions containing them
AP753A (en) Novel taxoids, preparation thereof and pharmaceutical compositions containing same.
US5576450A (en) Process for preparing taxoids
AU686690B2 (en) Novel taxoids, their preparation and pharmaceutical compositions containing them
US5906990A (en) Taxoids, preparation thereof, and pharmaceutical compositions containing same
US5556877A (en) Taxoids, their preparation and the pharmaceutical compositions which contain them
HU225032B1 (en) Novel taxoids, preparation thereof and pharmaceutical compositions containing the same
AU715228B2 (en) Taxoids, preparation thereof and pharmaceutical compositions containing same
US5959125A (en) Taxoids, preparation thereof, and pharmaceutical compositions containing same
AU704719B2 (en) Novel taxoids,their preparation and pharmaceutical compositions containing them
MXPA97007427A (en) New taxoids, its preparation and the pharmaceutical compositions that contain them
US20010051736A1 (en) Methods of treating cell lines expressing multidrug resistance P-glycoprotein
JPH10500979A (ja) 新規タキソイド類、その製造およびそれらを含む製薬学的組成物
US5968931A (en) Taxoids, preparation thereof and pharmaceutical compositions containing same
SK157196A3 (en) Taxoids, preparation and pharmaceutical compositions containing them
FR2721025A1 (fr) Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
MXPA97002742A (en) New taxoids, its preparation and the pharmaceutical compositions that contain them
MXPA96006061A (en) Taxoids, its preparation and the pharmaceutical compositions that contain them

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired