AU661067B2 - Dipyridamole for the treatment of proliferative diseases - Google Patents
Dipyridamole for the treatment of proliferative diseases Download PDFInfo
- Publication number
- AU661067B2 AU661067B2 AU28454/92A AU2845492A AU661067B2 AU 661067 B2 AU661067 B2 AU 661067B2 AU 28454/92 A AU28454/92 A AU 28454/92A AU 2845492 A AU2845492 A AU 2845492A AU 661067 B2 AU661067 B2 AU 661067B2
- Authority
- AU
- Australia
- Prior art keywords
- delivery
- local
- dipyridamole
- treatment
- proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 title claims description 53
- 229960002768 dipyridamole Drugs 0.000 title claims description 52
- 230000002062 proliferating effect Effects 0.000 title claims description 22
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims description 15
- 201000010099 disease Diseases 0.000 title claims description 14
- 238000012384 transportation and delivery Methods 0.000 claims description 40
- 238000000034 method Methods 0.000 claims description 30
- 230000004663 cell proliferation Effects 0.000 claims description 16
- 210000004027 cell Anatomy 0.000 claims description 15
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims description 11
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims description 11
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/795,434 US5270047A (en) | 1991-11-21 | 1991-11-21 | Local delivery of dipyridamole for the treatment of proliferative diseases |
| US795434 | 1991-11-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2845492A AU2845492A (en) | 1993-05-27 |
| AU661067B2 true AU661067B2 (en) | 1995-07-13 |
Family
ID=25165502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU28454/92A Ceased AU661067B2 (en) | 1991-11-21 | 1992-11-18 | Dipyridamole for the treatment of proliferative diseases |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5270047A (OSRAM) |
| EP (1) | EP0543653A1 (OSRAM) |
| JP (1) | JPH05201862A (OSRAM) |
| KR (1) | KR930009607A (OSRAM) |
| AU (1) | AU661067B2 (OSRAM) |
| CA (1) | CA2083223A1 (OSRAM) |
| HU (1) | HU212422B (OSRAM) |
| MX (1) | MX9206610A (OSRAM) |
| NO (1) | NO924461L (OSRAM) |
| RU (1) | RU2084224C1 (OSRAM) |
| TW (1) | TW252917B (OSRAM) |
| ZA (1) | ZA928832B (OSRAM) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
| US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6663881B2 (en) * | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| WO1994016706A1 (en) * | 1993-01-28 | 1994-08-04 | Neorx Corporation | Therapeutic inhibitors of vascular smooth muscle cells |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| ATE406909T1 (de) * | 1993-05-13 | 2008-09-15 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
| US5886026A (en) * | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| PT1155689E (pt) * | 1993-07-19 | 2007-01-31 | Angiotech Pharm Inc | Composições anti-angiogenicas e metodos de utilização |
| US5521191A (en) * | 1994-10-17 | 1996-05-28 | Washington University | Method for treatment of arterial stenosis |
| US5665591A (en) * | 1994-12-06 | 1997-09-09 | Trustees Of Boston University | Regulation of smooth muscle cell proliferation |
| US6558798B2 (en) | 1995-02-22 | 2003-05-06 | Scimed Life Systems, Inc. | Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity |
| US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| US7896914B2 (en) * | 1995-06-07 | 2011-03-01 | Cook Incorporated | Coated implantable medical device |
| US7550005B2 (en) * | 1995-06-07 | 2009-06-23 | Cook Incorporated | Coated implantable medical device |
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| US5171217A (en) * | 1991-02-28 | 1992-12-15 | Indiana University Foundation | Method for delivery of smooth muscle cell inhibitors |
-
1991
- 1991-11-21 US US07/795,434 patent/US5270047A/en not_active Expired - Fee Related
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1992
- 1992-11-16 RU RU9292004406A patent/RU2084224C1/ru active
- 1992-11-16 ZA ZA928832A patent/ZA928832B/xx unknown
- 1992-11-17 MX MX9206610A patent/MX9206610A/es not_active Application Discontinuation
- 1992-11-18 KR KR1019920021672A patent/KR930009607A/ko not_active Withdrawn
- 1992-11-18 CA CA002083223A patent/CA2083223A1/en not_active Abandoned
- 1992-11-18 TW TW081109231A patent/TW252917B/zh active
- 1992-11-18 JP JP4308615A patent/JPH05201862A/ja not_active Withdrawn
- 1992-11-18 AU AU28454/92A patent/AU661067B2/en not_active Ceased
- 1992-11-19 NO NO92924461A patent/NO924461L/no unknown
- 1992-11-19 HU HU9203626A patent/HU212422B/hu not_active IP Right Cessation
- 1992-11-19 EP EP92310577A patent/EP0543653A1/en not_active Withdrawn
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| KR930009607A (ko) | 1993-06-21 |
| AU2845492A (en) | 1993-05-27 |
| CA2083223A1 (en) | 1993-05-22 |
| NO924461D0 (no) | 1992-11-19 |
| JPH05201862A (ja) | 1993-08-10 |
| HU212422B (en) | 1996-06-28 |
| US5270047A (en) | 1993-12-14 |
| HU9203626D0 (en) | 1993-01-28 |
| EP0543653A1 (en) | 1993-05-26 |
| TW252917B (OSRAM) | 1995-08-01 |
| RU2084224C1 (ru) | 1997-07-20 |
| MX9206610A (es) | 1993-05-01 |
| HUT70034A (en) | 1995-09-28 |
| ZA928832B (en) | 1994-05-16 |
| NO924461L (no) | 1993-05-24 |
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