AU649952B2 - Method for antibody targeting of diagnostic or therapeutic agents - Google Patents
Method for antibody targeting of diagnostic or therapeutic agents Download PDFInfo
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- AU649952B2 AU649952B2 AU56736/90A AU5673690A AU649952B2 AU 649952 B2 AU649952 B2 AU 649952B2 AU 56736/90 A AU56736/90 A AU 56736/90A AU 5673690 A AU5673690 A AU 5673690A AU 649952 B2 AU649952 B2 AU 649952B2
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Arrangement Of Elements, Cooling, Sealing, Or The Like Of Lighting Devices (AREA)
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- Led Device Packages (AREA)
- Fastening Of Light Sources Or Lamp Holders (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/005441 WO1991008770A1 (en) | 1989-12-11 | 1989-12-11 | Method for antibody targeting of diagnostic or therapeutic agents |
Publications (2)
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| AU5673690A AU5673690A (en) | 1991-07-18 |
| AU649952B2 true AU649952B2 (en) | 1994-06-09 |
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| AU56736/90A Ceased AU649952B2 (en) | 1989-12-11 | 1989-12-11 | Method for antibody targeting of diagnostic or therapeutic agents |
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| EP (1) | EP0505357B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP3032287B2 (cg-RX-API-DMAC10.html) |
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| US5773435A (en) * | 1987-08-04 | 1998-06-30 | Bristol-Myers Squibb Company | Prodrugs for β-lactamase and uses thereof |
| US6610299B1 (en) | 1989-10-19 | 2003-08-26 | Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
| DE4106389A1 (de) * | 1991-02-28 | 1992-09-03 | Behringwerke Ag | Fusionsproteine zur prodrug-aktivierung, ihre herstellung und verwendung |
| US7241595B2 (en) | 1989-10-20 | 2007-07-10 | Sanofi-Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
| FI934857A7 (fi) * | 1992-03-04 | 1993-12-03 | Akzo Nv | Sitoutumisparin esikohdistus in vivo |
| US5965106A (en) * | 1992-03-04 | 1999-10-12 | Perimmune Holdings, Inc. | In vivo binding pair pretargeting |
| DE4233152A1 (de) | 1992-10-02 | 1994-04-07 | Behringwerke Ag | Antikörper-Enzym-Konjugate zur Prodrug-Aktivierung |
| US7011812B1 (en) | 1996-05-03 | 2006-03-14 | Immunomedics, Inc. | Targeted combination immunotherapy of cancer and infectious diseases |
| JPH1160499A (ja) * | 1997-08-22 | 1999-03-02 | Hiroshi Maeda | 抗腫瘍剤 |
| US6919076B1 (en) | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
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| FR2523445A1 (fr) * | 1982-03-17 | 1983-09-23 | Sanofi Sa | Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues |
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| NZ225599A (en) * | 1987-08-04 | 1991-09-25 | Bristol Myers Co | Antibody-enzyme conjugates and combinations with prodrugs for the treatment of tumour cells |
| GB8809616D0 (en) * | 1988-04-22 | 1988-05-25 | Cancer Res Campaign Tech | Further improvements relating to drug delivery systems |
| WO1990007929A1 (en) * | 1989-01-23 | 1990-07-26 | Akzo N.V. | Site specific in-vivo activation of therapeutic drugs |
| AU633867B2 (en) * | 1989-02-02 | 1993-02-11 | Eli Lilly And Company | Delivery of cytotoxic agents |
| DE3935016A1 (de) * | 1989-10-20 | 1991-04-25 | Behringwerke Ag | Glycosyl-etoposid-prodrugs, verfahren zu ihrer herstellung und ihre anwendung in kombination mit funktionalisiertem tumorspezifischen enzym-konjugaten |
-
1989
- 1989-12-11 WO PCT/US1989/005441 patent/WO1991008770A1/en not_active Ceased
- 1989-12-11 AT AT90908737T patent/ATE177321T1/de not_active IP Right Cessation
- 1989-12-11 AU AU56736/90A patent/AU649952B2/en not_active Ceased
- 1989-12-11 DE DE68928946T patent/DE68928946T2/de not_active Expired - Fee Related
- 1989-12-11 JP JP02508109A patent/JP3032287B2/ja not_active Expired - Fee Related
- 1989-12-11 EP EP90908737A patent/EP0505357B1/en not_active Expired - Lifetime
- 1989-12-11 KR KR1019910700828A patent/KR100236375B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0505357B1 (en) | 1999-03-10 |
| JPH05501543A (ja) | 1993-03-25 |
| WO1991008770A1 (en) | 1991-06-27 |
| EP0505357A1 (en) | 1992-09-30 |
| EP0505357A4 (cg-RX-API-DMAC10.html) | 1994-03-16 |
| KR920702819A (ko) | 1992-10-28 |
| ATE177321T1 (de) | 1999-03-15 |
| DE68928946D1 (de) | 1999-04-15 |
| KR100236375B1 (ko) | 1999-12-15 |
| AU5673690A (en) | 1991-07-18 |
| DE68928946T2 (de) | 1999-10-21 |
| JP3032287B2 (ja) | 2000-04-10 |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |