IL80973A
(en)
*
|
1985-12-20 |
1992-08-18 |
Sanofi Sa |
Modified ribosome-inactivating glycoproteins,their preparation,immunotoxins containing them and pharmaceutical compositions containing such immunotoxins
|
WO1989007641A1
(en)
*
|
1988-02-10 |
1989-08-24 |
Genzyme Corporation |
Enhancement of the therapeutic properties of glycoprotein
|
DE3927801A1
(en)
*
|
1989-08-23 |
1991-02-28 |
Hoechst Ag |
PROCESS FOR ENZYMATIC SYNTHESIS OF GALACTOSYLATED GLYCOPROTEIN COMPONENTS
|
AU675209B2
(en)
|
1991-10-15 |
1997-01-30 |
Scripps Research Institute, The |
Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
|
US6319695B1
(en)
*
|
1991-10-15 |
2001-11-20 |
The Scripps Research Insitute |
Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
DE4423131A1
(en)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
New hIL-4 mutant proteins as antagonists or partial agonists of human interleukin 4
|
SK284191B6
(en)
|
1995-02-24 |
2004-10-05 |
Genentech, Inc. |
Human DNASE I variants
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
US6020473A
(en)
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
US6998116B1
(en)
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
EP1500702A1
(en)
|
1996-04-01 |
2005-01-26 |
Genentech, Inc. |
APO-2LI and APO-3 apoptosis polypeptides from the TNFR1 familiy
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
US5990281A
(en)
*
|
1996-09-30 |
1999-11-23 |
Genentech, Inc. |
Vertebrate smoothened proteins
|
US6136958A
(en)
*
|
1996-09-30 |
2000-10-24 |
Genentech, Inc. |
Antibodies to vertebrate smoothened proteins
|
WO1998033924A1
(en)
|
1997-01-31 |
1998-08-06 |
Genentech, Inc. |
O-fucosyltransferase
|
US6342369B1
(en)
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
EP1003856A1
(en)
|
1997-06-05 |
2000-05-31 |
Board of Regents, The University of Texas System |
Apaf-1, the ced-4 human homolog, an activator of caspase-3
|
AU740227B2
(en)
|
1997-06-18 |
2001-11-01 |
Genentech Inc. |
Apo-2DcR
|
EP1659131B1
(en)
|
1997-09-17 |
2009-11-04 |
Genentech, Inc. |
Polypeptides and nucleic acids encoding the same
|
ES2306480T3
(en)
|
1997-09-18 |
2008-11-01 |
Genentech, Inc. |
DCR3 POLYPEPTIDE, A TNFR HOMOLOGIST.
|
EP1967587A1
(en)
|
1997-10-10 |
2008-09-10 |
Genentech, Inc. |
APO-3 Ligand
|
EP2014770A3
(en)
|
1997-10-29 |
2009-02-18 |
Genentech, Inc. |
WNT-1 Iinduced secreted polypeptide WISP-2
|
ES2316173T3
(en)
|
1997-10-29 |
2009-04-01 |
Genentech, Inc. |
INDUCIBLE GENES BY WNT-1.
|
US7192589B2
(en)
|
1998-09-16 |
2007-03-20 |
Genentech, Inc. |
Treatment of inflammatory disorders with STIgMA immunoadhesins
|
DE69840105D1
(en)
|
1997-11-21 |
2008-11-20 |
Genentech Inc |
PLATE-SPECIFIC ANTIGENES AND THEIR PHARMACEUTICAL USE
|
DE69939732D1
(en)
|
1998-01-15 |
2008-11-27 |
Genentech Inc |
APO-2 LIGAND
|
US6727079B1
(en)
|
1998-02-25 |
2004-04-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
cDNA encoding a gene BOG (B5T Over-expressed Gene) and its protein product
|
EP2050762A3
(en)
|
1998-03-10 |
2009-07-08 |
Genentech, Inc. |
Human cornichon-like protein and nucleic acids encoding it
|
IL138488A0
(en)
|
1998-03-17 |
2001-10-31 |
Genentech Inc |
Polypeptides homologous to vegf and bmp1
|
ES2292242T5
(en)
|
1998-05-15 |
2011-05-04 |
Genentech, Inc. |
THERAPEUTIC USES OF IL-17 HOMOLOGICAL POLYPEPTIDES.
|
EP1865061A3
(en)
|
1998-05-15 |
2007-12-19 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
EP3112468A1
(en)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17 homologous polypeptides and therapeutic uses thereof
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
CA2450402A1
(en)
|
1998-12-22 |
2000-06-29 |
Genentech, Inc. |
Methods and compositions for inhibiting cancer cell growth comprising pro224
|
CA2354027A1
(en)
|
1998-12-23 |
2000-07-06 |
Genentech, Inc. |
Il-1 related polypeptides
|
AU5152700A
(en)
|
1999-06-15 |
2001-01-02 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
CA2496312A1
(en)
|
1999-12-01 |
2001-06-07 |
Kevin P. Baker |
Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same
|
DK1897945T3
(en)
|
1999-12-23 |
2012-05-07 |
Genentech Inc |
IL-17 homologous polypeptides and therapeutic uses thereof.
|
WO2001051510A2
(en)
|
2000-01-10 |
2001-07-19 |
Maxygen Holdings Ltd |
G-csf conjugates
|
AU785055B2
(en)
|
2000-01-13 |
2006-09-07 |
Genentech Inc. |
Novel stra6 polypeptides
|
WO2001058935A2
(en)
|
2000-02-11 |
2001-08-16 |
Maxygen Aps |
FACTOR VII OR VIIa-LIKE MOLECULES
|
US7101974B2
(en)
|
2000-03-02 |
2006-09-05 |
Xencor |
TNF-αvariants
|
EP2275549A1
(en)
|
2000-06-23 |
2011-01-19 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
CA2648048A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
EP2014298A3
(en)
|
2000-08-24 |
2009-10-07 |
Genentech, Inc. |
Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
|
EP1944317A3
(en)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6576452B1
(en)
|
2000-10-04 |
2003-06-10 |
Genencor International, Inc. |
2,5-diketo-L-gluconic acid reductases and methods of use
|
US6673580B2
(en)
|
2000-10-27 |
2004-01-06 |
Genentech, Inc. |
Identification and modification of immunodominant epitopes in polypeptides
|
US7820447B2
(en)
|
2000-12-22 |
2010-10-26 |
Sagres Discovery Inc. |
Compositions and methods for cancer
|
US7892730B2
(en)
|
2000-12-22 |
2011-02-22 |
Sagres Discovery, Inc. |
Compositions and methods for cancer
|
US7700274B2
(en)
|
2000-12-22 |
2010-04-20 |
Sagres Discovery, Inc. |
Compositions and methods in cancer associated with altered expression of KCNJ9
|
US20030232334A1
(en)
|
2000-12-22 |
2003-12-18 |
Morris David W. |
Novel compositions and methods for cancer
|
US7645441B2
(en)
|
2000-12-22 |
2010-01-12 |
Sagres Discovery Inc. |
Compositions and methods in cancer associated with altered expression of PRLR
|
YU48703A
(en)
|
2001-02-27 |
2006-05-25 |
Maxygen Aps |
New interferon beta-like molecules
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
MXPA03011985A
(en)
|
2001-06-20 |
2004-03-26 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor.
|
WO2003020892A2
(en)
|
2001-08-29 |
2003-03-13 |
Genentech, Inc. |
Bv8 NUCLEIC ACIDS AND POLYPEPTIDES WITH MITOGENIC ACTIVITY
|
ES2390531T3
(en)
|
2001-09-18 |
2012-11-13 |
Genentech, Inc. |
Compositions and procedures for the diagnosis and treatment of tumor
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7439043B2
(en)
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7226903B2
(en)
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7265084B2
(en)
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7125843B2
(en)
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
DK1578771T3
(en)
|
2001-10-10 |
2013-06-10 |
Novo Nordisk As |
Remodeling and glycoconjugation of peptides
|
US7399613B2
(en)
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7265085B2
(en)
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US8008252B2
(en)
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7297511B2
(en)
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
EP2322229B1
(en)
|
2001-10-10 |
2016-12-21 |
Novo Nordisk A/S |
Remodeling and glycoconjugation of Factor IX
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7157277B2
(en)
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7473680B2
(en)
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
WO2003046150A2
(en)
|
2001-11-28 |
2003-06-05 |
Neose Technologies, Inc. |
Glycoprotein remodeling using endoglycanases
|
EP2067472A1
(en)
|
2002-01-02 |
2009-06-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2003072714A2
(en)
|
2002-02-21 |
2003-09-04 |
Wyeth |
Follistatin domain containing proteins
|
EP1575480A4
(en)
|
2002-02-22 |
2008-08-06 |
Genentech Inc |
Compositions and methods for the treatment of immune related diseases
|
EP1485477B1
(en)
|
2002-02-25 |
2009-05-13 |
Genentech, Inc. |
Novel type-1 cytokine receptor glm-r
|
EP2093233A1
(en)
|
2002-03-21 |
2009-08-26 |
Sagres Discovery, Inc. |
Novel compositions and methods in cancer
|
NZ535925A
(en)
|
2002-04-16 |
2008-06-30 |
Genentech Inc |
An isolated antibody that binds to a particular polypeptide
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
EP1553912A4
(en)
|
2002-06-07 |
2007-08-08 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2004004649A2
(en)
|
2002-07-08 |
2004-01-15 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
JP2006515159A
(en)
|
2002-08-02 |
2006-05-25 |
ワイエス |
MK2 interacting protein
|
CN101792749B
(en)
|
2002-08-12 |
2012-09-05 |
金克克国际有限公司 |
Mutant colibacillus appa phytase enzymes
|
EP1539228B1
(en)
|
2002-09-11 |
2010-12-29 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
AU2003276874B2
(en)
|
2002-09-11 |
2009-09-03 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
US20070010434A1
(en)
|
2002-09-16 |
2007-01-11 |
Genetech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
EP2500438A3
(en)
|
2002-09-25 |
2012-11-28 |
Genentech, Inc. |
Novel compositions and methods for the treatment of psoriasis
|
EP2322201A3
(en)
|
2002-10-29 |
2011-07-27 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
CA2503748A1
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
JP2011516026A
(en)
|
2002-11-26 |
2011-05-26 |
ジェネンテック・インコーポレーテッド |
Compositions and methods for the treatment of immune related diseases
|
TWI330641B
(en)
|
2002-12-24 |
2010-09-21 |
Yasuhiro Kajihara |
Sugar chain asparagine derivatives
|
US7553930B2
(en)
|
2003-01-06 |
2009-06-30 |
Xencor, Inc. |
BAFF variants and methods thereof
|
US7767387B2
(en)
|
2003-06-13 |
2010-08-03 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
US20070149449A1
(en)
|
2003-02-14 |
2007-06-28 |
Morris David W |
Therapeutic targets in cancer
|
US20040170982A1
(en)
|
2003-02-14 |
2004-09-02 |
Morris David W. |
Novel therapeutic targets in cancer
|
FR2851471B1
(en)
*
|
2003-02-24 |
2006-07-28 |
Synt Em |
COMPOUNDS COMPRISING AT LEAST ONE ACTIVE SUBSTANCE AND AT LEAST ONE VECTOR CONNECTED BY A BINDING AGENT, USES THEREOF AND THE BINDING AGENTS
|
MXPA05009743A
(en)
|
2003-03-12 |
2006-03-09 |
Genentech Inc |
Use of bv8 and/or eg-vegf to promote hematopoiesis.
|
NZ542306A
(en)
|
2003-03-14 |
2008-04-30 |
Wyeth Corp |
Antibodies against human IL-21 receptor and uses therefor
|
NZ542094A
(en)
|
2003-03-14 |
2008-12-24 |
Neose Technologies Inc |
Branched polymer conjugates comprising a peptide and water-soluble polymer chains
|
ES2383014T3
(en)
|
2003-04-02 |
2012-06-15 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor I and their uses
|
WO2006127896A2
(en)
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated factor ix
|
SG155777A1
(en)
|
2003-04-09 |
2009-10-29 |
Neose Technologies Inc |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7691603B2
(en)
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
US7709610B2
(en)
|
2003-05-08 |
2010-05-04 |
Facet Biotech Corporation |
Therapeutic use of anti-CS1 antibodies
|
EP1624847B1
(en)
|
2003-05-09 |
2012-01-04 |
BioGeneriX AG |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
RU2005136988A
(en)
|
2003-05-30 |
2006-06-10 |
Дженентек, Инк. (Us) |
ANTIBODY TREATMENT AGAINST VEGF
|
KR100835786B1
(en)
|
2003-07-08 |
2008-06-09 |
제넨테크, 인크. |
- il-17a/f heterologous polypeptides and therapeutic uses thereof
|
AR046071A1
(en)
|
2003-07-10 |
2005-11-23 |
Hoffmann La Roche |
ANTIBODIES AGAINST RECEIVER I OF THE INSULINAL TYPE GROWTH FACTOR AND THE USES OF THE SAME
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
WO2005019258A2
(en)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
EP2327723A3
(en)
|
2003-10-10 |
2012-06-27 |
Xencor, Inc. |
Protein based tnf-alpha variants for the treatment of tnf-alpha related disorders
|
JP4901478B2
(en)
|
2003-11-17 |
2012-03-21 |
ジェネンテック, インコーポレイテッド |
Compositions and methods for the treatment of tumors of hematopoietic origin
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7842661B2
(en)
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US7405198B2
(en)
|
2003-11-24 |
2008-07-29 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7956032B2
(en)
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
PT2311873T
(en)
|
2004-01-07 |
2018-11-20 |
Novartis Vaccines & Diagnostics Inc |
M-csf-specific monoclonal antibody and uses thereof
|
EP1765853B1
(en)
|
2004-01-08 |
2015-10-28 |
ratiopharm GmbH |
O-linked glycosylation of G-CSF peptides
|
CA2561533C
(en)
|
2004-04-13 |
2015-06-16 |
Yvo Graus |
Anti-p-selectin antibodies
|
RU2006138181A
(en)
|
2004-05-04 |
2008-06-10 |
Ново Нордиск Хелс Кеа Аг (Ch) |
O-RELATED Glycoforms of Polypeptides and a Method for Their Production
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
US20060024677A1
(en)
|
2004-07-20 |
2006-02-02 |
Morris David W |
Novel therapeutic targets in cancer
|
EP1771474B1
(en)
|
2004-07-20 |
2010-01-27 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
ES2710048T3
(en)
|
2004-07-23 |
2019-04-22 |
Acceleron Pharma Inc |
Antagonist antibodies to the ActRII receptor
|
WO2006031811A2
(en)
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
EP3061461A1
(en)
|
2004-10-29 |
2016-08-31 |
ratiopharm GmbH |
Remodeling and glycopegylation of fibroblast growth factor (fgf)
|
DK2325207T3
(en)
|
2004-11-12 |
2017-06-06 |
Xencor Inc |
Fc variants with altered binding to FcRn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
DE602005022928D1
(en)
|
2004-11-30 |
2010-09-23 |
Abgenix Inc |
ANTIBODIES AGAINST GPNMB AND ITS USES
|
ES2449195T3
(en)
|
2005-01-10 |
2014-03-18 |
Ratiopharm Gmbh |
Glycopegylated granulocyte colony stimulating factor
|
US20060263357A1
(en)
|
2005-05-05 |
2006-11-23 |
Tedder Thomas F |
Anti-CD19 antibody therapy for autoimmune disease
|
KR101289537B1
(en)
|
2005-02-15 |
2013-07-31 |
듀크 유니버시티 |
Anti-cd19 antibodies and uses in oncology
|
US9820986B2
(en)
|
2005-03-04 |
2017-11-21 |
Taiwan Hopaz Chems, Mfg. Co., Ltd. |
Glycopeptide compositions
|
TW200720289A
(en)
|
2005-04-01 |
2007-06-01 |
Hoffmann La Roche |
Antibodies against CCR5 and uses thereof
|
JP2008535853A
(en)
|
2005-04-07 |
2008-09-04 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド |
Cancer-related genes
|
CA2604885A1
(en)
|
2005-04-07 |
2006-10-19 |
Guoying Yu |
Cacna1e in cancer diagnosis, detection and treatment
|
WO2006121569A2
(en)
|
2005-04-08 |
2006-11-16 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
SG162728A1
(en)
|
2005-05-27 |
2010-07-29 |
Biogen Idec Inc |
Tweak binding antibodies
|
WO2006132788A2
(en)
|
2005-06-06 |
2006-12-14 |
Genentech, Inc. |
Transgenic models for different genes and their use for gene characterization
|
WO2008018854A2
(en)
|
2005-06-06 |
2008-02-14 |
The Rockefeller University |
Bactiophage lysins for bacillus anthracis
|
US7582291B2
(en)
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
AU2006280321A1
(en)
|
2005-08-15 |
2007-02-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
US8105585B2
(en)
|
2005-08-24 |
2012-01-31 |
The Rockefeller Universtiy |
Ply-GBS mutant lysins
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
WO2007056858A1
(en)
|
2005-11-18 |
2007-05-24 |
Glenmark Pharmaceuticals S.A. |
Anti-alpha2 integrin antibodies and their uses
|
AU2006335053A1
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
KR101557375B1
(en)
|
2005-11-23 |
2015-10-08 |
악셀레론 파마 인코포레이티드 |
Activin-actrπa antagonists and uses for promoting bone growth
|
WO2007114979A2
(en)
|
2006-02-17 |
2007-10-11 |
Genentech, Inc. |
Gene disruptons, compositions and methods relating thereto
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
TWI417301B
(en)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
Antibodies against human il-22 and uses therefor
|
EP2540741A1
(en)
|
2006-03-06 |
2013-01-02 |
Aeres Biomedical Limited |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
US8278421B2
(en)
|
2006-03-20 |
2012-10-02 |
Xoma Techolology Ltd. |
Human antibodies specific for gastrin materials and methods
|
US7846724B2
(en)
|
2006-04-11 |
2010-12-07 |
Hoffmann-La Roche Inc. |
Method for selecting CHO cell for production of glycosylated antibodies
|
US20090288176A1
(en)
|
2006-04-19 |
2009-11-19 |
Genentech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
TWI395754B
(en)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
Humanized c-kit antibody
|
US20080274958A1
(en)
|
2006-07-21 |
2008-11-06 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
CN101626783A
(en)
|
2006-08-04 |
2010-01-13 |
诺华有限公司 |
EPHB3-specific antibody and its application
|
EP3415532A1
(en)
|
2006-08-18 |
2018-12-19 |
XOMA Technology Ltd. |
Prlr-specific antibody and uses thereof
|
US8349801B2
(en)
|
2006-09-18 |
2013-01-08 |
Compugen Ltd. |
Peptide ligands for G-protein coupled receptors
|
BRPI0717512A2
(en)
|
2006-09-29 |
2013-11-19 |
Hoffmann La Roche |
CCR5 ANTIBODIES AND USES OF THE SAME
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
US8969532B2
(en)
|
2006-10-03 |
2015-03-03 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
|
MX2009003470A
(en)
|
2006-10-04 |
2009-04-14 |
Novo Nordisk As |
Glycerol linked pegylated sugars and glycopeptides.
|
US20080254512A1
(en)
|
2006-11-02 |
2008-10-16 |
Capon Daniel J |
Hybrid immunoglobulins with moving parts
|
CN111518218A
(en)
|
2006-11-02 |
2020-08-11 |
阿塞勒隆制药公司 |
ALK1 receptor and ligand antagonists and uses thereof
|
WO2008070780A1
(en)
|
2006-12-07 |
2008-06-12 |
Novartis Ag |
Antagonist antibodies against ephb3
|
TWI432449B
(en)
|
2007-02-02 |
2014-04-01 |
Acceleron Pharma Inc |
Variants derived from actriib and uses therefor
|
EP2481415B1
(en)
|
2007-02-09 |
2019-09-11 |
Acceleron Pharma Inc. |
Pharmaceutical compositions comprising Activin-ActRIIA antagonists
|
KR101508397B1
(en)
|
2007-02-22 |
2015-04-08 |
제넨테크, 인크. |
Methods for detecting inflammatory bowel disease
|
NZ580030A
(en)
|
2007-04-03 |
2012-06-29 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
EP2703011A3
(en)
|
2007-05-07 |
2014-03-26 |
MedImmune, LLC |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
WO2008154639A2
(en)
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
CA2693651A1
(en)
|
2007-07-12 |
2009-01-15 |
Ronen Shemesh |
Bioactive peptides and method of using same
|
US9845355B2
(en)
|
2007-07-16 |
2017-12-19 |
Genentech, Inc. |
Humanized anti-CD79b antibodies and immunoconjugates and methods of use
|
PL2474557T3
(en)
|
2007-07-16 |
2015-02-27 |
Genentech Inc |
Anti-CD79b antibodies and immunoconjugates and methods of use
|
CN101361968B
(en)
|
2007-08-06 |
2011-08-03 |
健能隆医药技术(上海)有限公司 |
Use of interleukin-22 in treating fatty liver
|
EP3330292A1
(en)
|
2007-08-21 |
2018-06-06 |
Amgen, Inc |
Human c-fms antigen binding proteins
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
ES2672769T3
(en)
|
2007-08-29 |
2018-06-18 |
Sanofi |
Humanized anti-CXCR5 antibodies, derivatives thereof and their uses
|
DK2769729T3
(en)
|
2007-09-04 |
2019-04-23 |
Compugen Ltd |
POLYPEPTIDES AND POLYNUCLEOTIDES AND APPLICATIONS THEREOF AS A PHARMACEUTICAL OBJECTIVE FOR THE PRODUCTION OF MEDICINAL PRODUCTS AND BIOTECHNOLOGICAL PRODUCTS
|
EP3243524A1
(en)
|
2007-09-18 |
2017-11-15 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
ES2558155T3
(en)
|
2007-10-30 |
2016-02-02 |
Indiana University Research And Technology Corporation |
Compounds showing glucacon antagonist activity and GLP-1 agonist
|
US8414893B2
(en)
|
2007-12-21 |
2013-04-09 |
Amgen Inc. |
Anti-amyloid antibodies and uses thereof
|
EP4098661A1
(en)
|
2007-12-26 |
2022-12-07 |
Xencor, Inc. |
Fc variants with altered binding to fcrn
|
EP2238165B1
(en)
|
2008-01-07 |
2017-07-05 |
Government of the United States of America, as represented by the Secretary, Department of Health and Human Services |
Anti-hiv domain antibodies and method of making and using same
|
JP5701064B2
(en)
|
2008-01-25 |
2015-04-15 |
アムジエン・インコーポレーテツド |
Ferroportin antibody and method of use thereof
|
ES2618292T3
(en)
|
2008-01-31 |
2017-06-21 |
Inserm - Institut National De La Sante Et De La Recherche Medicale |
Antibodies against and use of human CD39 to inhibit the activity of regulatory T cells
|
RU2553566C2
(en)
|
2008-01-31 |
2015-06-20 |
Дженентек, Инк. |
ANTI-CD79b ANTIBODIES AND IMMUNOCONJUGATES AND METHODS FOR USING THEM
|
KR101582841B1
(en)
|
2008-02-27 |
2016-01-11 |
노보 노르디스크 에이/에스 |
Conjugated factor viii molecules
|
CN104655854A
(en)
|
2008-04-09 |
2015-05-27 |
健泰科生物技术公司 |
Novel compositions and methods for the treatment of immune related diseases
|
US9315577B2
(en)
|
2008-05-01 |
2016-04-19 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
CN105963695A
(en)
|
2008-05-02 |
2016-09-28 |
阿塞勒隆制药公司 |
Methods and compositions based on ALK1 antagonists for modulating angiogenesis and pericyte coverage
|
US8093018B2
(en)
|
2008-05-20 |
2012-01-10 |
Otsuka Pharmaceutical Co., Ltd. |
Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
|
TWI541023B
(en)
|
2008-06-17 |
2016-07-11 |
印第安納大學科技研究公司 |
Glucagon analogs exhibiting enhanced solubility and stability in physiological ph buffers
|
EA020326B9
(en)
|
2008-06-17 |
2015-03-31 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Gip-based mixed agonists for treatment of metabolic disorders and obesity
|
CL2009001424A1
(en)
|
2008-06-17 |
2010-04-30 |
Univ Indiana Res & Tech Corp |
Glucagon-like peptide; dimer comprising two of said peptides; pharmaceutical composition comprising it; and its use to treat diabetes or induce weight loss.
|
EP2307456B1
(en)
|
2008-06-27 |
2014-10-15 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
TW201803586A
(en)
|
2008-08-14 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
Use of GDF traps to increase red blood cell levels
|
CN102282172B
(en)
|
2008-09-07 |
2014-02-19 |
台湾醣联生技医药股份有限公司 |
Anti-extended type i glycosphingolipid antibody, derivatives thereof and use
|
US8481033B2
(en)
|
2008-10-07 |
2013-07-09 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Neutralizing antibodies and fragments thereof directed against platelet factor-4 variant 1 (PF4V1)
|
AU2009312532B2
(en)
|
2008-11-06 |
2013-05-16 |
Ichnos Sciences SA |
Treatment with anti-alpha2 integrin antibodies
|
US20110293605A1
(en)
|
2008-11-12 |
2011-12-01 |
Hasige Sathish |
Antibody formulation
|
EP2865689A1
(en)
|
2008-12-08 |
2015-04-29 |
Compugen Ltd. |
FAM26F polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
|
CA2747499A1
(en)
|
2008-12-19 |
2010-06-24 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
JP5755566B2
(en)
|
2008-12-19 |
2015-07-29 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
Amide insulin prodrug
|
JO3382B1
(en)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
Human cgrp receptor binding antibodies
|
US8952130B2
(en)
|
2009-02-24 |
2015-02-10 |
The Salk Institute For Biological Studies |
Designer ligands of TGF-β superfamily
|
WO2010106051A1
(en)
|
2009-03-17 |
2010-09-23 |
Universite De La Mediterranee |
Btla antibodies and uses thereof
|
EP2233500A1
(en)
|
2009-03-20 |
2010-09-29 |
LFB Biotechnologies |
Optimized Fc variants
|
JP2012521197A
(en)
|
2009-03-20 |
2012-09-13 |
アムジエン・インコーポレーテツド |
Carrier immunoglobulin and use thereof
|
CA2756206A1
(en)
|
2009-03-27 |
2010-09-30 |
Academia Sinica |
Methods and compositions for immunization against virus
|
WO2010111617A2
(en)
|
2009-03-27 |
2010-09-30 |
Van Andel Research Institute |
Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
|
EP3702001A1
(en)
|
2009-03-30 |
2020-09-02 |
Acceleron Pharma Inc. |
Bmp-alk3 antagonists and uses for promoting bone growth
|
NZ595574A
(en)
|
2009-04-01 |
2013-11-29 |
Genentech Inc |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
US8580732B2
(en)
|
2009-04-07 |
2013-11-12 |
Duke University |
Peptide therapy for hyperglycemia
|
EP2248903A1
(en)
|
2009-04-29 |
2010-11-10 |
Universitat Autònoma De Barcelona |
Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
|
BRPI1010587A2
(en)
|
2009-06-08 |
2019-04-09 |
Acceleron Pharma Inc. |
Methods to Increase Thermogenic Adipocytes
|
ES2836534T3
(en)
|
2009-06-12 |
2021-06-25 |
Acceleron Pharma Inc |
Truncated ActRIIB-Fc fusion proteins
|
MX2011013625A
(en)
|
2009-06-16 |
2012-01-20 |
Univ Indiana Res & Tech Corp |
Gip receptor-active glucagon compounds.
|
NZ623113A
(en)
|
2009-08-13 |
2015-10-30 |
Acceleron Pharma Inc |
Combined use of gdf traps and erythropoietin receptor activators to increase red blood cell levels
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
IN2012DN02766A
(en)
|
2009-09-09 |
2015-09-18 |
Acceleron Pharma Inc |
|
WO2011032099A1
(en)
|
2009-09-11 |
2011-03-17 |
The Board Of Trustees Of The University Of Illinois |
Methods of treating diastolic dysfunction and related conditions
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
EP2480888B1
(en)
|
2009-09-25 |
2016-11-30 |
XOMA Technology Ltd. |
Screening methods
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
CN102656266B
(en)
|
2009-10-15 |
2016-08-03 |
霍夫曼-拉罗奇有限公司 |
There is the chimeric fibroblast growth factor of the receptor-specific of change
|
RU2539772C2
(en)
|
2009-10-22 |
2015-01-27 |
Дженентек, Инк. |
Methods and compositions for hepsin modulation of macrophage-stimulating protein
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
AU2010311567B2
(en)
|
2009-10-26 |
2015-03-26 |
Chugai Seiyaku Kabushiki Kaisha |
Method for the production of a glycosylated immunoglobulin
|
JO3244B1
(en)
|
2009-10-26 |
2018-03-08 |
Amgen Inc |
Human il-23 antigen binding proteins
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
WO2011056572A1
(en)
|
2009-10-27 |
2011-05-12 |
The Board Of Trustees Of The University Of Illinois |
Methods of diagnosing diastolic dysfunction
|
EP3818988A1
(en)
|
2009-11-03 |
2021-05-12 |
Acceleron Pharma Inc. |
Methods for treating fatty liver disease
|
JP6267425B2
(en)
|
2009-11-17 |
2018-01-24 |
アクセルロン ファーマ, インコーポレイテッド |
ACTRIIB protein and its variants and uses thereof for utrophin induction for the treatment of muscular dystrophy
|
CA2781532A1
(en)
|
2009-11-20 |
2011-05-26 |
Amgen Inc. |
Anti-orai1 antigen binding protein that binds the second extracellular loop of orai1
|
PE20121584A1
(en)
|
2009-11-30 |
2012-11-29 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMORS
|
US9428586B2
(en)
|
2009-12-01 |
2016-08-30 |
Compugen Ltd |
Heparanase splice variant
|
US8722615B2
(en)
|
2009-12-02 |
2014-05-13 |
Acceleron Pharma, Inc. |
Compositions and methods for increasing serum half-life
|
UA109888C2
(en)
|
2009-12-07 |
2015-10-26 |
|
ANTIBODY OR ANTIBODILITY ANTIBODY OR ITS BINDING TO THE β-CLOTE, FGF RECEPTORS AND THEIR COMPLEXES
|
US8703701B2
(en)
|
2009-12-18 |
2014-04-22 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
RU2012136450A
(en)
|
2010-01-27 |
2014-03-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
CONJUGATES GLUCAGON ANTAGONIST - GIP AGONIST AND COMPOSITIONS FOR TREATMENT OF METABOLIC DISORDERS AND OBESITY
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
KR20130004579A
(en)
|
2010-02-23 |
2013-01-11 |
제넨테크, 인크. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP3590966A1
(en)
|
2010-02-23 |
2020-01-08 |
Sanofi |
Anti-alpha2 integrin antibodies and their uses
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
CN103119054B
(en)
|
2010-03-26 |
2017-01-18 |
达特茅斯大学理事会 |
VISTA regulatory T cell mediator protein, VISTA binding agents and use thereof
|
EP2558497A2
(en)
|
2010-04-15 |
2013-02-20 |
Amgen Inc. |
Human fgf receptor and beta-klotho binding proteins
|
CN107090045A
(en)
|
2010-05-03 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
Composition and method for tumor diagnosis and therapy
|
US20120135912A1
(en)
|
2010-05-10 |
2012-05-31 |
Perseid Therapeutics Llc |
Polypeptide inhibitors of vla4
|
US9127088B2
(en)
|
2010-05-13 |
2015-09-08 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
|
JP2013530187A
(en)
|
2010-06-17 |
2013-07-25 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
Compositions and methods for treating inflammatory diseases.
|
RU2580317C2
(en)
|
2010-06-24 |
2016-04-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Peptide pro-drugs of amide glucagon superfamily
|
JP5912112B2
(en)
|
2010-06-24 |
2016-04-27 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
Amide insulin prodrug
|
EP3202415B1
(en)
|
2010-06-30 |
2021-12-08 |
Compugen Ltd. |
Fusion protein comprising a c1orf32 polypeptide and one or more domains of an immunoglobulin heavy chain constant region for treatment of multiple sclerosis, rheumatoid arthritis and other autoimmune disorders.
|
WO2012010696A1
(en)
|
2010-07-23 |
2012-01-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for cancer management targeting co-029
|
EP3029066B1
(en)
|
2010-07-29 |
2019-02-20 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
US8999335B2
(en)
|
2010-09-17 |
2015-04-07 |
Compugen Ltd. |
Compositions and methods for treatment of drug resistant multiple myeloma
|
US8993727B2
(en)
|
2010-09-22 |
2015-03-31 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
WO2012045085A1
(en)
|
2010-10-01 |
2012-04-05 |
Oxford Biotherapeutics Ltd. |
Anti-rori antibodies
|
TWI537385B
(en)
|
2010-11-04 |
2016-06-11 |
中央研究院 |
Methods for producing virus particles with simplified glycosylation of surface proteins
|
WO2012080769A1
(en)
|
2010-12-15 |
2012-06-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-cd277 antibodies and uses thereof
|
SG191194A1
(en)
|
2010-12-22 |
2013-07-31 |
Univ Indiana Res & Tech Corp |
Glucagon analogs exhibiting gip receptor activity
|
EP2654789B1
(en)
|
2010-12-22 |
2018-05-30 |
Orega Biotech |
Antibodies against human cd39 and use thereof
|
WO2012090150A2
(en)
|
2010-12-27 |
2012-07-05 |
Compugen Ltd |
New cell-penetrating peptides and uses thereof
|
JOP20210044A1
(en)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
Anti-cd38 antibodies
|
WO2012101125A1
(en)
|
2011-01-24 |
2012-08-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Specific antibodies against human cxcl4 and uses thereof
|
AR085911A1
(en)
|
2011-03-16 |
2013-11-06 |
Sanofi Sa |
SAFE THERAPEUTIC DOSE OF A SIMILAR PROTEIN TO AN ANTIBODY WITH VUAL REGION
|
EP2691419B1
(en)
|
2011-03-31 |
2016-11-09 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Antibodies directed against icos and uses thereof
|
US9409987B2
(en)
|
2011-04-15 |
2016-08-09 |
Compugen Ltd |
Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
|
CN108341863A
(en)
|
2011-04-20 |
2018-07-31 |
阿塞勒隆制药公司 |
Endoglin polypeptide and application thereof
|
WO2012156532A1
(en)
|
2011-05-19 |
2012-11-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-human-her3 antibodies and uses thereof
|
SG10201902706VA
(en)
|
2011-06-03 |
2019-04-29 |
Xoma Technology Ltd |
Antibodies specific for tgf-beta
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
JP6179864B2
(en)
|
2011-06-22 |
2017-08-16 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
Glucagon / GLP-1 receptor co-agonist
|
AU2012277376B2
(en)
|
2011-06-30 |
2016-11-24 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
AU2012279237B2
(en)
|
2011-07-01 |
2016-09-29 |
Ngm Biopharmaceuticals, Inc. |
Compositions, uses and methods for treatment of metabolic disorders and diseases
|
EP2543677A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
EP2543678A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
EP2543679A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
US8987422B2
(en)
|
2011-09-22 |
2015-03-24 |
Amgen Inc. |
CD27L antigen binding proteins
|
AU2012318306A1
(en)
|
2011-10-06 |
2014-04-24 |
The Board Of Trustees Of The University Of Illinois |
Myosin binding protein- C for use in methods relating to diastolic heart failure
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
DK2766392T3
(en)
|
2011-10-10 |
2019-10-07 |
Xencor Inc |
PROCEDURE FOR CLEANING ANTIBODIES
|
BR112014009528B1
(en)
|
2011-10-17 |
2020-12-29 |
Acceleron Pharma, Inc. |
uses of actriib polypeptides for the manufacture of a drug to treat ineffective erythropoiesis
|
BR112014007124A2
(en)
|
2011-11-17 |
2017-06-13 |
Univ Indiana Res & Tech Corp |
superfamily of gluxagon peptides that exhibit glucocorticoid receptor activity
|
JP6635655B2
(en)
|
2011-12-08 |
2020-01-29 |
アムジエン・インコーポレーテツド |
Human LCAT antigen binding proteins and their use in therapy
|
US20150045301A1
(en)
|
2011-12-16 |
2015-02-12 |
Kalos Therapeutics, Inc. |
Methods and uses of anp (atrial natriuretic peptide), bnp (brain natriuretic peptide) and cnp (c-type natriuretic peptide)-related peptides and derivatives thereof for treatment of retinal disorders and diseases
|
JP6392123B2
(en)
|
2011-12-20 |
2018-09-19 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
CTP-based insulin analog for diabetes treatment
|
IN2014KN00848A
(en)
|
2012-02-01 |
2015-10-02 |
Compugen Ltd |
|
MX2014009277A
(en)
|
2012-02-02 |
2015-03-03 |
Acceleron Pharma Inc |
Alk1 antagonists and their uses in treating renal cell carcinoma.
|
AU2013234046B2
(en)
|
2012-03-16 |
2017-09-07 |
University Health Network |
Methods and compositions for modulating Toso activity
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
US9809636B2
(en)
|
2012-04-06 |
2017-11-07 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels comprising administering BMP9
|
US10385395B2
(en)
|
2012-04-11 |
2019-08-20 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
PL3431492T3
(en)
|
2012-04-27 |
2021-07-05 |
Novo Nordisk A/S |
Human cd30 ligand antigen binding proteins
|
EP2847219A1
(en)
|
2012-05-07 |
2015-03-18 |
Amgen Inc. |
Anti-erythropoietin antibodies
|
UY34813A
(en)
|
2012-05-18 |
2013-11-29 |
Amgen Inc |
ANTIGEN UNION PROTEINS DIRECTED AGAINST ST2 RECEIVER
|
KR20150023729A
(en)
|
2012-06-14 |
2015-03-05 |
암브룩스, 인코포레이티드 |
Anti-psma antibodies conjugated to nuclear receptor ligand polypeptides
|
BR112014031671A2
(en)
|
2012-06-21 |
2018-08-07 |
Hoffmann La Roche |
glucagon analogs exhibiting gip receptor activity
|
MX2014015558A
(en)
|
2012-06-21 |
2015-03-05 |
Univ Indiana Res & Tech Corp |
Glucagon analogs exhibiting gip receptor activity.
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
US9676847B2
(en)
|
2012-06-25 |
2017-06-13 |
Orega Biotech |
IL-17 antagonist antibodies
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
EP3613765A1
(en)
|
2012-08-03 |
2020-02-26 |
Dana-Farber Cancer Institute, Inc. |
Antibody against repulsive guidance molecule b (rgmb)
|
ES2684552T3
(en)
|
2012-09-03 |
2018-10-03 |
Inserm - Institut National De La Santé Et De La Recherche Médicale |
Antibodies directed against ICOS to treat graft versus host disease
|
AU2013312211B2
(en)
|
2012-09-07 |
2018-03-29 |
King's College London |
VISTA modulators for diagnosis and treatment of cancer
|
EP2912462B1
(en)
|
2012-10-24 |
2019-08-07 |
Celgene Corporation |
Biomarker for use in treating anemia
|
MX366336B
(en)
|
2012-11-02 |
2019-07-05 |
Celgene Corp |
Activin-actrii antagonists and uses for treating bone and other disorders.
|
PT2922875T
(en)
|
2012-11-20 |
2017-05-31 |
Sanofi Sa |
Anti-ceacam5 antibodies and uses thereof
|
ES2828505T3
(en)
|
2012-11-28 |
2021-05-26 |
Ngm Biopharmaceuticals Inc |
Compositions and methods for the treatment of metabolic disorders and diseases
|
TW201425336A
(en)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
BCMA antigen binding proteins
|
EP3686218A1
(en)
|
2012-12-10 |
2020-07-29 |
Biogen MA Inc. |
Anti-blood dendritic cell antigen 2 antibodies and uses thereof
|
SG11201504920SA
(en)
|
2012-12-27 |
2015-07-30 |
Sanofi Sa |
Anti-lamp1 antibodies and antibody drug conjugates, and uses thereof
|
RU2675514C2
(en)
|
2012-12-27 |
2018-12-19 |
ЭнДжиЭм БАЙОФАРМАСЬЮТИКАЛЗ, ИНК. |
Methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
US10717965B2
(en)
|
2013-01-10 |
2020-07-21 |
Gloriana Therapeutics, Inc. |
Mammalian cell culture-produced neublastin antibodies
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
CA3211863A1
(en)
|
2013-01-14 |
2014-07-17 |
Xencor, Inc. |
Novel heterodimeric proteins
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
AU2014207549B2
(en)
|
2013-01-15 |
2018-12-06 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
JO3519B1
(en)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
Antibody constructs for CDH19 and CD3
|
WO2014114801A1
(en)
|
2013-01-25 |
2014-07-31 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
EP3888671A3
(en)
|
2013-03-11 |
2022-01-05 |
Amgen Inc. |
Protein formulations
|
WO2014159764A1
(en)
|
2013-03-14 |
2014-10-02 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
WO2014145174A1
(en)
|
2013-03-15 |
2014-09-18 |
Biological Mimetics, Inc. |
Immunogenic human rhinovirus (hrv) compositions
|
US10035859B2
(en)
|
2013-03-15 |
2018-07-31 |
Biogen Ma Inc. |
Anti-alpha V beta 6 antibodies and uses thereof
|
HUE045859T2
(en)
|
2013-03-15 |
2020-01-28 |
Amgen Res Munich Gmbh |
Single chain binding molecules comprising n-terminal abp
|
PE20151673A1
(en)
|
2013-03-15 |
2015-11-27 |
Genentech Inc |
IL-22 POLYPEPTIDES AND IL-22 Fc FUSION PROTEINS AND METHODS OF USE
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
WO2014144911A2
(en)
|
2013-03-15 |
2014-09-18 |
Capon Daniel J |
Hybrid immunoglobulin containing non-peptidyl linkage
|
WO2014151680A1
(en)
|
2013-03-15 |
2014-09-25 |
Biogen Idec Ma Inc. |
Treatment and prevention of acute kidney injury using anti-alpha v beta 5 antibodies
|
US10544187B2
(en)
|
2013-03-15 |
2020-01-28 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
WO2014144553A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Secreted frizzle-related protein 5 (sfrp5) binding proteins and methods of treatment
|
WO2014143739A2
(en)
|
2013-03-15 |
2014-09-18 |
Biogen Idec Ma Inc. |
Anti-alpha v beta 6 antibodies and uses thereof
|
AU2014228924B2
(en)
|
2013-03-15 |
2019-04-18 |
Amgen Inc. |
Human PAC1 antibodies
|
EP2968508B1
(en)
|
2013-03-15 |
2022-04-27 |
Sanofi Pasteur Biologics, LLC |
Antibodies against clostridium difficile toxins and methods of using the same
|
KR102561553B1
(en)
|
2013-03-15 |
2023-07-31 |
젠코어 인코포레이티드 |
Heterodimeric proteins
|
CN105263514B
(en)
|
2013-03-15 |
2019-04-26 |
本质生命科学有限公司 |
Anti- hepcidin antibody and application thereof
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
WO2014183885A1
(en)
|
2013-05-17 |
2014-11-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antagonist of the btla/hvem interaction for use in therapy
|
MX351127B
(en)
|
2013-05-30 |
2017-10-03 |
Kiniksa Pharmaceuticals Ltd |
Oncostatin m receptor antigen binding proteins.
|
PL3036320T3
(en)
|
2013-08-19 |
2021-11-02 |
Biogen Ma Inc. |
Control of protein glycosylation by culture medium supplementation and cell culture process parameters
|
US20160237399A1
(en)
|
2015-02-18 |
2016-08-18 |
Biogen Ma Inc. |
Control of Protein Glycosylation by Culture Medium Supplementation and Cell Culture Process Parameters
|
US20150056199A1
(en)
|
2013-08-22 |
2015-02-26 |
Acceleron Pharma, Inc. |
Tgf-beta receptor type ii variants and uses thereof
|
TW201605896A
(en)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
GITR antigen binding proteins
|
AR097648A1
(en)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
COMBINATION OF EPIGENETIC FACTORS AND BIESPECTIVE COMPOUNDS THAT HAVE LIKE DIANA CD33 AND CD3 IN THE TREATMENT OF MYELOID LEUKEMIA
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
US10081682B2
(en)
|
2013-10-11 |
2018-09-25 |
Oxford Bio Therapeutics Ltd. |
Conjugated antibodies against LY75 for the treatment of cancer
|
WO2015057939A1
(en)
|
2013-10-18 |
2015-04-23 |
Biogen Idec Ma Inc. |
Anti-s1p4 antibodies and uses thereof
|
KR102354787B1
(en)
|
2013-10-25 |
2022-01-24 |
악셀레론 파마 인코포레이티드 |
Endoglin peptides to treat fibrotic diseases
|
ES2759252T3
(en)
|
2013-10-31 |
2020-05-08 |
Resolve Therapeutics Llc |
Nuclease-albumin fusions and therapeutic methods
|
CN104623637A
(en)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Application of IL-22 dimer in preparation of intravenous injection drugs
|
JP2017500017A
(en)
|
2013-12-20 |
2017-01-05 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
Use of perfusion seed cultures to improve biopharmaceutical fed-batch production capacity and product quality
|
EP3087098B1
(en)
|
2013-12-24 |
2020-04-08 |
Janssen Pharmaceutica NV |
Anti-vista antibodies and fragments
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
KR102472816B1
(en)
|
2014-02-20 |
2022-11-30 |
알러간, 인코포레이티드 |
Complement component c5 antibodies
|
BR112016019825A2
(en)
|
2014-02-27 |
2017-10-17 |
Allergan Inc |
complement factor bb antibodies
|
CA2941697A1
(en)
|
2014-03-07 |
2015-09-11 |
University Health Network |
Methods and compositions for modifying the immune response
|
LT3701971T
(en)
|
2014-03-14 |
2023-01-10 |
Biomolecular Holdings Llc |
Compounds useful in preparing hybrid immunoglobulin containing non-peptidyl linkage
|
US11124760B2
(en)
|
2014-03-24 |
2021-09-21 |
Biogen Ma Inc. |
Methods for overcoming glutamine deprivation during mammalian cell culture
|
AU2015237184B2
(en)
|
2014-03-28 |
2020-11-26 |
Xencor, Inc. |
Bispecific antibodies that bind to CD38 and CD3
|
WO2015158851A1
(en)
|
2014-04-16 |
2015-10-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the prevention or the treatment of bleeding episodes
|
FR3020063A1
(en)
|
2014-04-16 |
2015-10-23 |
Gamamabs Pharma |
ANTI-HER4 HUMAN ANTIBODY
|
US10654926B2
(en)
|
2014-05-02 |
2020-05-19 |
Medimmune Limited |
P2X4 antibodies and uses thereof
|
AU2015269333B2
(en)
|
2014-06-04 |
2020-05-07 |
Acceleron Pharma, Inc. |
Methods and compositions for treatment of disorders with follistatin polypeptides
|
CN107073109B
(en)
|
2014-06-11 |
2021-08-06 |
凯西·A·格林 |
Use of VISTA agonists and antagonists to inhibit or enhance humoral immunity
|
MX2017000319A
(en)
|
2014-07-09 |
2017-04-27 |
Midori Usa Inc |
Oligosaccharide compositions and methods for producing thereof.
|
AR101400A1
(en)
|
2014-07-31 |
2016-12-14 |
Amgen Res (Munich) Gmbh |
INDIVIDUAL CHAIN INDIVIDUAL CHAIN ANTIBODY CONSTRUCTION WITH IMPROVED FABRIC DISTRIBUTION
|
TW201609812A
(en)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
Optimized cross-species specific bispecific single chain antibody constructs
|
AR101669A1
(en)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
ANTIBODY CONSTRUCTS FOR CDH19 AND CD3
|
EP3185885B1
(en)
|
2014-08-26 |
2020-08-19 |
Compugen Ltd. |
Polypeptides and uses thereof as a drug for treatment of autoimmune disorders
|
EP3575316A1
(en)
|
2014-08-27 |
2019-12-04 |
Amgen, Inc |
Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
|
WO2016040767A2
(en)
|
2014-09-12 |
2016-03-17 |
Amgen Inc. |
Chrdl-1 epitopes and antibodies
|
NZ730186A
(en)
|
2014-09-22 |
2020-04-24 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
MY180054A
(en)
|
2014-09-30 |
2020-11-20 |
Neurimmune Holding Ag |
Human-derived anti-dipeptide repeats (dprs) antibody
|
MA41685A
(en)
|
2014-10-17 |
2017-08-22 |
Biogen Ma Inc |
COPPER SUPPLEMENT FOR THE REGULATION OF GLYCOSYLATION IN A MAMMAL CELL CULTURE PROCESS
|
AU2015335029B2
(en)
|
2014-10-24 |
2021-09-23 |
Astrazeneca Ab |
Combination
|
US10603359B2
(en)
|
2014-10-30 |
2020-03-31 |
Acceleron Pharma Inc. |
Methods and compositions using GDF15 polypeptides for increasing red blood cells
|
MA40864A
(en)
|
2014-10-31 |
2017-09-05 |
Biogen Ma Inc |
HYPOTAURINE, GABA, BETA-ALANINE AND CHOLINE FOR THE REGULATION OF THE ACCUMULATION OF RESIDUAL BY-PRODUCTS IN MAMMAL CELL CULTURE PROCESSES
|
WO2016069889A1
(en)
|
2014-10-31 |
2016-05-06 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-transferrin fusions and methods
|
US11033637B2
(en)
|
2014-11-21 |
2021-06-15 |
University Of Maryland, Baltimore |
Targeted structure-specific particulate delivery systems
|
CU24597B1
(en)
|
2014-11-26 |
2022-05-11 |
Xencor Inc |
HETERODIMERIC BIESPECIFIC ANTIBODIES THAT BIND CD3 AND CD20
|
TN2017000222A1
(en)
|
2014-11-26 |
2018-10-19 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and cd38
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
MD4801C1
(en)
|
2014-12-03 |
2022-10-31 |
Celgene Corporation |
Activin-ActRII antagonists and uses for treating myelodysplastic syndromes
|
EP3226900A4
(en)
|
2014-12-05 |
2018-09-19 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
AU2015360903B2
(en)
|
2014-12-08 |
2021-03-25 |
Dana-Farber Cancer Institute, Inc. |
Methods for upregulating immune responses using combinations of anti-RGMB and anti-PD-1 agents
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
RS60916B1
(en)
|
2015-01-23 |
2020-11-30 |
Sanofi Sa |
Anti-cd3 antibodies, anti-cd123 antibodies and bispecific antibodies specifically binding to cd3 and/or cd123
|
BR112017015944B1
(en)
|
2015-01-26 |
2022-03-22 |
Cadena Bio, Inc |
Animal feed composition, animal feed premix, use and method for producing an animal feed composition
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
US10167334B2
(en)
|
2015-04-03 |
2019-01-01 |
Xoma Technology Ltd. |
Treatment of cancer using anti-TGF-BETA and PD-1 antibodies
|
UA126270C2
(en)
|
2015-04-10 |
2022-09-14 |
Емджен Інк. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
CN116063541A
(en)
|
2015-04-17 |
2023-05-05 |
安进研发(慕尼黑)股份有限公司 |
Bispecific antibody constructs for CDH3 and CD3
|
US20160347848A1
(en)
|
2015-05-28 |
2016-12-01 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
WO2016207717A1
(en)
|
2015-06-24 |
2016-12-29 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
WO2017009712A1
(en)
|
2015-07-13 |
2017-01-19 |
Compugen Ltd. |
Hide1 compositions and methods
|
TWI717375B
(en)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for cd70 and cd3
|
TW202346349A
(en)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for dll3 and cd3
|
TWI796283B
(en)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for msln and cd3
|
TWI829617B
(en)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for flt3 and cd3
|
TWI744242B
(en)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for egfrviii and cd3
|
EP4218792A1
(en)
|
2015-08-04 |
2023-08-02 |
Acceleron Pharma Inc. |
Composition for treating myeloproliferative disorders
|
WO2017058944A1
(en)
|
2015-09-29 |
2017-04-06 |
Amgen Inc. |
Asgr inhibitors
|
US11207393B2
(en)
|
2015-10-16 |
2021-12-28 |
President And Fellows Of Harvard College |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses
|
CA3007030A1
(en)
|
2015-12-07 |
2017-06-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
JOP20170017B1
(en)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
Pharmaceutical composition comprising bispecific antibody constructs
|
WO2017134158A1
(en)
|
2016-02-03 |
2017-08-10 |
Amgen Research (Munich) Gmbh |
Psma and cd3 bispecific t cell engaging antibody constructs
|
EA039859B1
(en)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Bispecific antibody constructs binding egfrviii and cd3
|
DK3411402T3
(en)
|
2016-02-03 |
2022-02-07 |
Amgen Res Munich Gmbh |
BCMA AND CD3 BISPECIFIC T-CELL INVOLVING ANTIBODY CONSTRUCTIONS
|
MX2018009800A
(en)
|
2016-02-12 |
2018-11-09 |
Janssen Pharmaceutica Nv |
Anti-vista (b7h5) antibodies.
|
EP3442579A4
(en)
|
2016-04-15 |
2019-12-18 |
Immunext Inc. |
Anti-human vista antibodies and use thereof
|
EP3442562B1
(en)
|
2016-04-15 |
2022-09-21 |
Evive Biotechnology (Shanghai) Ltd |
An il-22 dimer for use in treating necrotizing enterocolitis
|
JOP20170091B1
(en)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
Administration of a bispecific construct binding to CD33 and CD3 for use in a method for the treatment of myeloid leukemia
|
WO2017189483A1
(en)
|
2016-04-25 |
2017-11-02 |
The Johns Hopkins University |
Znt8 assays for drug development and pharmaceutical compositions
|
JP7422480B2
(en)
|
2016-05-04 |
2024-01-26 |
アムジエン・インコーポレーテツド |
Interleukin-2 mutant protein for regulatory T cell proliferation
|
EP3464337A4
(en)
|
2016-05-31 |
2019-12-18 |
Mogam Institute for Biomedical Research |
Ab6 family designer ligands of tgf-beta superfamily
|
WO2017218707A2
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
KR20190020341A
(en)
|
2016-06-28 |
2019-02-28 |
젠코어 인코포레이티드 |
Heterozygous antibodies that bind to somatostatin receptor 2
|
MA45554A
(en)
|
2016-07-01 |
2019-05-08 |
Resolve Therapeutics Llc |
OPTIMIZED BINUCLEASE FUSIONS.
|
CN117330747A
(en)
|
2016-07-15 |
2024-01-02 |
武田药品工业株式会社 |
Methods and materials for assessing response to plasmacytoid and plasma cell depleting therapies
|
TWI790206B
(en)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
Bispecific antibody-like binding proteins specifically binding to cd3 and cd123
|
WO2018022479A1
(en)
|
2016-07-25 |
2018-02-01 |
Biogen Ma Inc. |
Anti-hspa5 (grp78) antibodies and uses thereof
|
JP7148493B2
(en)
|
2016-08-01 |
2022-10-05 |
ゾーマ (ユーエス) リミテッド ライアビリティ カンパニー |
Parathyroid hormone receptor 1 (PTH1R) antibodies and uses thereof
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP2019531070A
(en)
|
2016-09-15 |
2019-10-31 |
アクセレロン ファーマ インコーポレーテッド |
Twisted gas torsion polypeptide and uses thereof
|
WO2018064098A1
(en)
|
2016-09-28 |
2018-04-05 |
Cohbar, Inc. |
Therapeutic mots-c related peptides
|
MX2019003543A
(en)
|
2016-09-28 |
2019-06-17 |
Xoma Us Llc |
Antibodies that bind interleukin-2 and uses thereof.
|
JP7142630B2
(en)
|
2016-10-14 |
2022-09-27 |
ゼンコア インコーポレイテッド |
IL15/IL15Rα heterodimeric FC-fusion protein
|
TW202300515A
(en)
|
2016-10-20 |
2023-01-01 |
法商賽諾菲公司 |
Anti-chikv antibodies and uses thereof
|
AU2018205888B2
(en)
|
2017-01-05 |
2021-09-02 |
Kahr Medical Ltd. |
A PD1-41BBL fusion protein and methods of use thereof
|
ES2916217T3
(en)
|
2017-01-05 |
2022-06-29 |
Kahr Medical Ltd |
A SIRP1 ALPHA-41BBL fusion protein and methods of using the same
|
JOP20190189A1
(en)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
Low ph pharmaceutical composition comprising t cell engaging antibody constructs
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
WO2018156892A1
(en)
|
2017-02-23 |
2018-08-30 |
Adrx, Inc. |
Peptide inhibitors of transcription factor aggregation
|
MX2019010848A
(en)
|
2017-03-16 |
2019-10-30 |
Innate Pharma |
Compositions and methods for treating cancer.
|
EP3615569A1
(en)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
WO2018204594A1
(en)
|
2017-05-04 |
2018-11-08 |
Acceleron Pharma Inc. |
Tgf-beta receptor type ii fusion proteins and uses thereof
|
UY37726A
(en)
|
2017-05-05 |
2018-11-30 |
Amgen Inc |
PHARMACEUTICAL COMPOSITION THAT INCLUDES BISPECTIFIC ANTIBODY CONSTRUCTIONS FOR IMPROVED STORAGE AND ADMINISTRATION
|
US20230137562A1
(en)
|
2017-06-07 |
2023-05-04 |
Adrx, Inc. |
Tau aggregation inhibitors
|
US11084863B2
(en)
|
2017-06-30 |
2021-08-10 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains
|
US11892457B2
(en)
|
2017-07-12 |
2024-02-06 |
The Johns Hopkins University |
Proteoliposome-based ZnT8 self-antigen for type 1 diabetes diagnosis
|
CN111094334A
(en)
|
2017-07-19 |
2020-05-01 |
美国卫生与公众服务部 |
Antibodies and methods for diagnosis and treatment of hepatitis B virus infection
|
RS63101B1
(en)
|
2017-08-03 |
2022-04-29 |
Amgen Inc |
Interleukin-21 muteins and methods of treatment
|
CA3073062A1
(en)
|
2017-08-18 |
2019-02-21 |
Adrx, Inc. |
Tau aggregation peptide inhibitors
|
MX2020002070A
(en)
|
2017-08-22 |
2020-03-24 |
Sanabio Llc |
Soluble interferon receptors and uses thereof.
|
TWI731264B
(en)
|
2017-09-08 |
2021-06-21 |
美商安進公司 |
Inhibitors of kras g12c and methods of using the same
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
US11312770B2
(en)
|
2017-11-08 |
2022-04-26 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
EP3724229A1
(en)
|
2017-12-11 |
2020-10-21 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
WO2019125732A1
(en)
|
2017-12-19 |
2019-06-27 |
Xencor, Inc. |
Engineered il-2 fc fusion proteins
|
UY38041A
(en)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
CONSTRUCTION OF BIESPECFIC ANTIBODY DIRECTED TO MUC17 AND CD3
|
EP3737694B1
(en)
|
2018-01-12 |
2023-03-01 |
Amgen Inc. |
Anti-pd-1 antibodies and methods of treatment
|
RU2020127792A
(en)
|
2018-01-26 |
2022-02-28 |
Дженентек, Инк. |
IL-22-Fc fusion proteins AND METHODS OF APPLICATION
|
LT3743088T
(en)
|
2018-01-26 |
2022-12-27 |
F. Hoffmann-La Roche Ag |
Il-22 fc compositions and methods of use
|
AU2019222705A1
(en)
|
2018-02-14 |
2020-10-01 |
Horizon Therapeutics Ireland Dac |
Antibodies to feline McDonough sarcoma (FMS)-like tyrosine kinase 3 receptor ligand (FLT3L) and uses thereof for treating autoimmune and inflammatory diseases
|
SG11202007694UA
(en)
|
2018-02-21 |
2020-09-29 |
Genentech Inc |
DOSING FOR TREATMENT WITH IL-22 Fc FUSION PROTEINS
|
EP3773911A2
(en)
|
2018-04-04 |
2021-02-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
JP2021521784A
(en)
|
2018-04-18 |
2021-08-30 |
ゼンコア インコーポレイテッド |
PD-1 targeted heterodimer fusion proteins containing IL-15 / IL-15RaFc fusion proteins and PD-1 antigen binding domains and their use
|
CA3097741A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
US20210171610A1
(en)
|
2018-05-02 |
2021-06-10 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
CA3099893A1
(en)
|
2018-06-18 |
2019-12-26 |
Innate Pharma |
Compositions and methods for treating cancer
|
CN112584859A
(en)
|
2018-07-02 |
2021-03-30 |
美国安进公司 |
anti-STEAP 1 antigen binding proteins
|
CN112543773A
(en)
|
2018-07-11 |
2021-03-23 |
卡尔医学有限公司 |
SIRP alpha-4-1 BBL variant fusion proteins and methods of use thereof
|
MX2021001221A
(en)
|
2018-07-30 |
2021-06-23 |
Amgen Res Munich Gmbh |
Prolonged administration of a bispecific antibody construct binding to cd33 and cd3.
|
KR20210042117A
(en)
|
2018-08-03 |
2021-04-16 |
암젠 리서치 (뮌헨) 게엠베하 |
Antibody constructs against CLDN18.2 and CD3
|
CN113166241A
(en)
|
2018-08-16 |
2021-07-23 |
约翰霍普金斯大学 |
Human ZNT8 antibodies
|
CN113195523A
(en)
|
2018-10-03 |
2021-07-30 |
Xencor股份有限公司 |
IL-12 heterodimer Fc fusion proteins
|
AU2019356564A1
(en)
|
2018-10-11 |
2021-04-29 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
CN113597319A
(en)
|
2019-01-04 |
2021-11-02 |
分解治疗有限责任公司 |
Treatment of xerosis with nuclease fusion proteins
|
EP3917944A1
(en)
|
2019-01-28 |
2021-12-08 |
Cohbar Inc. |
Therapeutic peptides
|
EP3693023A1
(en)
|
2019-02-11 |
2020-08-12 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
US20220080053A1
(en)
|
2019-02-07 |
2022-03-17 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
KR20210136014A
(en)
|
2019-02-12 |
2021-11-16 |
암브룩스, 인코포레이티드 |
Compositions, methods and uses thereof containing antibody-TLR agonist conjugates
|
WO2020180726A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
CA3131705A1
(en)
|
2019-03-27 |
2020-10-01 |
Umc Utrecht Holding B.V. |
Engineered iga antibodies and methods of use
|
MX2021012160A
(en)
|
2019-04-08 |
2022-01-06 |
Biogen Ma Inc |
Anti-integrin antibodies and uses thereof.
|
BR112021019128A2
(en)
|
2019-04-09 |
2022-01-04 |
Abcuro Inc |
Killer cell lectin-like receptor (klrg1) member 1 subfamily depleting antibodies
|
AU2020290573A1
(en)
|
2019-06-13 |
2021-11-04 |
Amgen Inc. |
Automated biomass-based perfusion control in the manufacturing of biologics
|
US20220267409A1
(en)
|
2019-07-11 |
2022-08-25 |
Kahr Medical Ltd. |
Heterodimers and methods of use thereof
|
US20210032370A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Recruiting agent further binding an mhc molecule
|
DE102019121007A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins that specifically bind to MAGE-A
|
JP2022543259A
(en)
|
2019-08-02 |
2022-10-11 |
オレガ・バイオテック |
Novel IL-17B antibody
|
CA3150441A1
(en)
|
2019-08-13 |
2021-02-18 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
AU2020381536A1
(en)
|
2019-11-13 |
2022-04-21 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
AU2020407208A1
(en)
|
2019-12-17 |
2022-06-02 |
Amgen Inc. |
Dual interleukin-2 /tnf receptor agonist for use in therapy
|
WO2021144020A1
(en)
|
2020-01-15 |
2021-07-22 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding prame
|
EP4093771A1
(en)
|
2020-01-22 |
2022-11-30 |
Amgen Research (Munich) GmbH |
Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
|
US20230146593A1
(en)
|
2020-03-12 |
2023-05-11 |
Amgen Inc. |
Method for treatment and prophylaxis of crs in patients comprising a combination of bispecific antibodies binding to cds x cancer cell and tnf alpha or il-6 inhibitor
|
WO2021207662A1
(en)
|
2020-04-10 |
2021-10-14 |
Genentech, Inc. |
Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
CA3183756A1
(en)
|
2020-05-19 |
2021-11-25 |
Amgen Inc. |
Mageb2 binding constructs
|
CA3183693A1
(en)
|
2020-05-29 |
2021-12-02 |
Amgen Inc. |
Adverse effects-mitigating administration of a bispecific construct binding to cd33 and cd3
|
EP4169949A1
(en)
|
2020-06-23 |
2023-04-26 |
Jiangsu Kanion Pharmaceutical Co., Ltd. |
Anti-cd38 antibody and use thereof
|
CA3165342A1
(en)
|
2020-06-29 |
2022-01-06 |
James Arthur Posada |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
TW202216778A
(en)
|
2020-07-15 |
2022-05-01 |
美商安進公司 |
Tigit and cd112r blockade
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
CA3190606A1
(en)
|
2020-08-20 |
2022-02-24 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
JP2023540732A
(en)
|
2020-09-04 |
2023-09-26 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Anti-CEACAM5 antibodies and conjugates and uses thereof
|
EP4240767A1
(en)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
Polypeptide constructs binding to cd3
|
EP4240407A1
(en)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
Antigen binding domain with reduced clipping rate
|
KR20230098334A
(en)
|
2020-11-06 |
2023-07-03 |
암젠 리서치 (뮌헨) 게엠베하 |
Polypeptide constructs that selectively bind to CLDN6 and CD3
|
CN116323671A
(en)
|
2020-11-06 |
2023-06-23 |
安进公司 |
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|
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(en)
|
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|