AU604868B2 - 3-(substituted-(pyrazolo/s-triazolo)(1,5-a) pyrimidinylthiomethyl)-7-acyl-cephalosporin derivatives - Google Patents

3-(substituted-(pyrazolo/s-triazolo)(1,5-a) pyrimidinylthiomethyl)-7-acyl-cephalosporin derivatives Download PDF

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Publication number
AU604868B2
AU604868B2 AU14309/88A AU1430988A AU604868B2 AU 604868 B2 AU604868 B2 AU 604868B2 AU 14309/88 A AU14309/88 A AU 14309/88A AU 1430988 A AU1430988 A AU 1430988A AU 604868 B2 AU604868 B2 AU 604868B2
Authority
AU
Australia
Prior art keywords
methyl
carboxylic acid
ene
oxo
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU14309/88A
Other languages
English (en)
Other versions
AU1430988A (en
Inventor
Andre Furlenmeier
Erwin Gotschi
Paul Hebeisen
Werner Hofheinz
Helmut Link
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Pharmaceutical Development Institute Co
Sankei Pharmaceutical Co Ltd
Original Assignee
Sankei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankei Pharmaceutical Co Ltd filed Critical Sankei Pharmaceutical Co Ltd
Publication of AU1430988A publication Critical patent/AU1430988A/en
Application granted granted Critical
Publication of AU604868B2 publication Critical patent/AU604868B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
AU14309/88A 1987-04-10 1988-04-06 3-(substituted-(pyrazolo/s-triazolo)(1,5-a) pyrimidinylthiomethyl)-7-acyl-cephalosporin derivatives Ceased AU604868B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH140787 1987-04-10
CH1407/87 1987-04-10
CH165787 1987-04-30
CH1657/87 1987-04-30
CH241387 1987-06-26
CH2413/87 1987-06-26

Publications (2)

Publication Number Publication Date
AU1430988A AU1430988A (en) 1988-10-13
AU604868B2 true AU604868B2 (en) 1991-01-03

Family

ID=27172951

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14309/88A Ceased AU604868B2 (en) 1987-04-10 1988-04-06 3-(substituted-(pyrazolo/s-triazolo)(1,5-a) pyrimidinylthiomethyl)-7-acyl-cephalosporin derivatives

Country Status (14)

Country Link
EP (1) EP0286145A3 (xx)
JP (1) JPS63258479A (xx)
KR (1) KR880012612A (xx)
AU (1) AU604868B2 (xx)
DK (1) DK179388A (xx)
FI (1) FI881650A (xx)
HU (1) HU201947B (xx)
IL (1) IL85972A0 (xx)
MC (1) MC1921A1 (xx)
NO (1) NO881531L (xx)
NZ (1) NZ224129A (xx)
PH (1) PH25104A (xx)
PT (1) PT87201A (xx)
YU (2) YU70988A (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI872879A (fi) * 1986-07-21 1988-01-22 Sankei Yakuhin Kk --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes.
NZ225383A (en) * 1987-08-07 1990-03-27 Sankei Yakuhin Kk Cephalosporin derivatives and pharmaceutical compositions
US5030724A (en) * 1990-01-22 1991-07-09 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
US5077432A (en) * 1990-01-22 1991-12-31 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
US5972026A (en) 1997-04-07 1999-10-26 Broncus Technologies, Inc. Bronchial stenter having diametrically adjustable electrodes
US6488673B1 (en) 1997-04-07 2002-12-03 Broncus Technologies, Inc. Method of increasing gas exchange of a lung
US6273907B1 (en) 1997-04-07 2001-08-14 Broncus Technologies, Inc. Bronchial stenter
US7027869B2 (en) 1998-01-07 2006-04-11 Asthmatx, Inc. Method for treating an asthma attack
US6200333B1 (en) 1997-04-07 2001-03-13 Broncus Technologies, Inc. Bronchial stenter
US7921855B2 (en) 1998-01-07 2011-04-12 Asthmatx, Inc. Method for treating an asthma attack
US8181656B2 (en) 1998-06-10 2012-05-22 Asthmatx, Inc. Methods for treating airways
US7198635B2 (en) 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
US8251070B2 (en) 2000-03-27 2012-08-28 Asthmatx, Inc. Methods for treating airways
US7104987B2 (en) 2000-10-17 2006-09-12 Asthmatx, Inc. Control system and process for application of energy to airway walls and other mediums
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
AU2009244058B2 (en) 2008-05-09 2015-07-02 Nuvaira, Inc Systems, assemblies, and methods for treating a bronchial tree
WO2011056684A2 (en) 2009-10-27 2011-05-12 Innovative Pulmonary Solutions, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
US9149328B2 (en) 2009-11-11 2015-10-06 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US9770293B2 (en) 2012-06-04 2017-09-26 Boston Scientific Scimed, Inc. Systems and methods for treating tissue of a passageway within a body
WO2014018153A1 (en) 2012-07-24 2014-01-30 Boston Scientific Scimed, Inc. Electrodes for tissue treatment
US9272132B2 (en) 2012-11-02 2016-03-01 Boston Scientific Scimed, Inc. Medical device for treating airways and related methods of use
US9283374B2 (en) 2012-11-05 2016-03-15 Boston Scientific Scimed, Inc. Devices and methods for delivering energy to body lumens
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
EP3335658B1 (en) 2013-08-09 2020-04-22 Boston Scientific Scimed, Inc. Expandable catheter

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586229B2 (en) * 1985-04-01 1989-07-06 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
AU597695B2 (en) * 1986-07-21 1990-06-07 Nippon Pharmaceutical Development Institute Company Limited Cephalosporin derivatives
AU599169B2 (en) * 1986-11-25 1990-07-12 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
AU586215B2 (en) * 1985-01-21 1989-07-06 Nippon Pharmaceutical Development Institute Company Limited Novel ```-lactam antibiotics

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586229B2 (en) * 1985-04-01 1989-07-06 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
AU597695B2 (en) * 1986-07-21 1990-06-07 Nippon Pharmaceutical Development Institute Company Limited Cephalosporin derivatives
AU599169B2 (en) * 1986-11-25 1990-07-12 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives

Also Published As

Publication number Publication date
KR880012612A (ko) 1988-11-28
IL85972A0 (en) 1988-09-30
PH25104A (en) 1991-02-19
YU123689A (en) 1991-06-30
MC1921A1 (fr) 1989-04-06
NZ224129A (en) 1991-02-26
FI881650A0 (fi) 1988-04-08
YU70988A (en) 1989-12-31
HUT46919A (en) 1988-12-28
EP0286145A2 (en) 1988-10-12
DK179388A (da) 1988-10-11
NO881531L (no) 1988-10-11
JPS63258479A (ja) 1988-10-25
AU1430988A (en) 1988-10-13
FI881650A (fi) 1988-10-11
EP0286145A3 (en) 1990-10-10
HU201947B (en) 1991-01-28
NO881531D0 (no) 1988-04-08
DK179388D0 (da) 1988-03-30
PT87201A (pt) 1989-05-12

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