AU604226B2 - Method of modifying the lipid structure function and expression of cell membranes and pharmaceutical compositions for use therein - Google Patents

Method of modifying the lipid structure function and expression of cell membranes and pharmaceutical compositions for use therein Download PDF

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Publication number
AU604226B2
AU604226B2 AU68724/87A AU6872487A AU604226B2 AU 604226 B2 AU604226 B2 AU 604226B2 AU 68724/87 A AU68724/87 A AU 68724/87A AU 6872487 A AU6872487 A AU 6872487A AU 604226 B2 AU604226 B2 AU 604226B2
Authority
AU
Australia
Prior art keywords
acid
cells
stearic acid
cell
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU68724/87A
Other languages
English (en)
Other versions
AU6872487A (en
Inventor
Kosta Apostolov
William Roland Barker
Christopher Barry Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868603621A external-priority patent/GB8603621D0/en
Priority claimed from GB868630935A external-priority patent/GB8630935D0/en
Priority claimed from GB878701064A external-priority patent/GB8701064D0/en
Application filed by Individual filed Critical Individual
Publication of AU6872487A publication Critical patent/AU6872487A/en
Application granted granted Critical
Publication of AU604226B2 publication Critical patent/AU604226B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU68724/87A 1986-02-14 1987-02-12 Method of modifying the lipid structure function and expression of cell membranes and pharmaceutical compositions for use therein Expired - Fee Related AU604226B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8603621 1986-02-14
GB868603621A GB8603621D0 (en) 1986-02-14 1986-02-14 Modifying lipid structure of cell membranes
GB868630935A GB8630935D0 (en) 1986-12-24 1986-12-24 Cell receptor sites
GB8630935 1986-12-24
GB8701064 1987-01-16
GB878701064A GB8701064D0 (en) 1987-01-16 1987-01-16 Cell receptor sites & antigenic determinants

Publications (2)

Publication Number Publication Date
AU6872487A AU6872487A (en) 1987-08-20
AU604226B2 true AU604226B2 (en) 1990-12-13

Family

ID=27262923

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68724/87A Expired - Fee Related AU604226B2 (en) 1986-02-14 1987-02-12 Method of modifying the lipid structure function and expression of cell membranes and pharmaceutical compositions for use therein

Country Status (5)

Country Link
EP (1) EP0238198A3 (enExample)
AU (1) AU604226B2 (enExample)
DK (1) DK72187A (enExample)
IN (1) IN164555B (enExample)
NZ (1) NZ219230A (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU601021B2 (en) * 1987-03-11 1990-08-30 Molecular Diagnostics, Inc. Assay for necleic acid sequences in a sample
PT1315831E (pt) 2000-02-24 2010-11-04 Xenon Pharmaceuticals Inc Estearoil-coa dessaturase para identificar agentes terapêuticos que reduzem triglicéridos
DE60134995D1 (de) 2000-09-26 2008-09-04 Xenon Pharmaceuticals Inc Verfahren und zusammensetzungen, die eine stearoyl-coa desuturase-hscd5 verwenden
US7132529B2 (en) 2001-07-30 2006-11-07 Isis Pharmaceuticals, Inc. Antisense modulation of stearoyl-CoA desaturase expression
US20050043256A1 (en) 2001-07-30 2005-02-24 Isis Pharmaceuticals, Inc. Antisense modulation of stearoyl-CoA desaturase expression
EP2585057B1 (en) * 2010-06-25 2017-08-23 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Methods of treatment using sterculic acid

Also Published As

Publication number Publication date
DK72187D0 (da) 1987-02-13
EP0238198A3 (en) 1990-05-30
AU6872487A (en) 1987-08-20
DK72187A (da) 1987-10-23
NZ219230A (en) 1991-06-25
EP0238198A2 (en) 1987-09-23
IN164555B (enExample) 1989-04-08

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