AU580975B2 - Osteogenic factors - Google Patents

Osteogenic factors

Info

Publication number
AU580975B2
AU580975B2 AU37221/84A AU3722184A AU580975B2 AU 580975 B2 AU580975 B2 AU 580975B2 AU 37221/84 A AU37221/84 A AU 37221/84A AU 3722184 A AU3722184 A AU 3722184A AU 580975 B2 AU580975 B2 AU 580975B2
Authority
AU
Australia
Prior art keywords
protein
bone
osteogenic factors
inducing
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU37221/84A
Other languages
English (en)
Other versions
AU3722184A (en
Inventor
Arup Sen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
International Genetic Engineering Inc
Original Assignee
International Genetic Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Genetic Engineering Inc filed Critical International Genetic Engineering Inc
Publication of AU3722184A publication Critical patent/AU3722184A/en
Application granted granted Critical
Publication of AU580975B2 publication Critical patent/AU580975B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Magnetic Heads (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU37221/84A 1984-01-04 1984-12-28 Osteogenic factors Expired AU580975B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56816784A 1984-01-04 1984-01-04
US568167 1984-01-04

Publications (2)

Publication Number Publication Date
AU3722184A AU3722184A (en) 1985-07-11
AU580975B2 true AU580975B2 (en) 1989-02-09

Family

ID=24270176

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37221/84A Expired AU580975B2 (en) 1984-01-04 1984-12-28 Osteogenic factors

Country Status (11)

Country Link
EP (1) EP0148155B1 (forum.php)
JP (1) JPS60226814A (forum.php)
AT (1) ATE42309T1 (forum.php)
AU (1) AU580975B2 (forum.php)
CA (1) CA1241641A (forum.php)
DE (1) DE3569542D1 (forum.php)
DK (1) DK161524C (forum.php)
GR (1) GR850006B (forum.php)
IE (1) IE57966B1 (forum.php)
NZ (1) NZ210699A (forum.php)
ZA (1) ZA8547B (forum.php)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
US4627982A (en) * 1984-07-16 1986-12-09 Collagen Corporation Partially purified bone-inducing factor
JPH0723322B2 (ja) * 1985-12-07 1995-03-15 克之 藤井 液状骨形成剤からなる注射液
US4877864A (en) * 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6432919B1 (en) 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
IL83003A (en) * 1986-07-01 1995-07-31 Genetics Inst Osteoinductive factors
DE3626414C2 (de) * 1986-08-05 1994-11-10 Robapharm Ag Präparat zur Stimulierung von Chondrocyten und Osteoblasten (Ossein-Hydroxyapatit-Komplex), Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
WO1993012803A1 (de) * 1986-10-22 1993-07-08 Krueger Wolfgang Wachstumstimulierendes material, herstellungsverfahren und therapeutische zusammensetzung
KR900700116A (ko) * 1988-04-06 1990-08-11 원본미기재 뼈-유도 단백질
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5258494A (en) 1988-04-08 1993-11-02 Stryker Corporation Osteogenic proteins
US6919308B2 (en) 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US5162114A (en) * 1989-02-23 1992-11-10 Stryker Corporation Bone collagen matrix for xenogenic implants
US5250302A (en) * 1988-04-08 1993-10-05 Stryker Corporation Osteogenic devices
US5324819A (en) * 1988-04-08 1994-06-28 Stryker Corporation Osteogenic proteins
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5670336A (en) * 1988-04-08 1997-09-23 Stryker Corporation Method for recombinant production of osteogenic protein
US5108753A (en) * 1988-04-08 1992-04-28 Creative Biomolecules Osteogenic devices
US4968590A (en) * 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
JP2548414B2 (ja) * 1988-04-08 1996-10-30 ストライカー・コーポレーション 生合成による骨形成蛋白質および該蛋白質を含む骨形成装置
EP0349048A3 (en) * 1988-06-27 1990-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth factors derived from regenerating bone marrow
US5106626A (en) * 1988-10-11 1992-04-21 International Genetic Engineering, Inc. Osteogenic factors
JPH03151877A (ja) * 1989-06-02 1991-06-28 Chiron Corp 骨カルシウム沈着因子
CA2020729A1 (en) * 1989-07-19 1991-01-20 Michael C. Kiefer Bone morphogenetic protein
ES2118723T3 (es) * 1989-10-17 1998-10-01 Stryker Corp Dispositivos osteogenicos.
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US5849686A (en) * 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US5972884A (en) * 1991-03-11 1999-10-26 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US7056882B2 (en) 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US6399569B1 (en) 1991-03-11 2002-06-04 Curis, Inc. Morphogen treatments for limiting proliferation of epithelial cells
US5652337A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. OP-3-induced morphogenesis
US6495513B1 (en) 1991-03-11 2002-12-17 Curis, Inc. Morphogen-enhanced survival and repair of neural cells
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US5656593A (en) * 1991-03-11 1997-08-12 Creative Biomolecules, Inc. Morphogen induced periodontal tissue regeneration
CA2104678C (en) 1991-03-11 2002-05-14 Charles M. Cohen Protein-induced morphogenesis
US6800603B2 (en) 1991-03-11 2004-10-05 Curis, Inc. Morphogen-induced neural cell adhesion
US6949505B1 (en) 1991-03-11 2005-09-27 Curis, Inc. Morphogen-induced dendritic growth
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
US6022853A (en) * 1991-08-30 2000-02-08 Creative Biomolecules, Inc. Morphogen-enriched dietary composition
EP0612348B1 (en) 1991-11-04 2003-04-23 Genetics Institute, LLC Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
DK0698094T3 (da) 1993-05-12 2004-05-03 Inst Genetics Llc BMP-11-sammensætninger
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
AU689184B2 (en) 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
US5928940A (en) * 1996-09-24 1999-07-27 Creative Biomolecules, Inc. Morphogen-responsive signal transducer and methods of use thereof
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
TWI329129B (en) 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
AU2003240196A1 (en) 2002-06-20 2004-01-23 Nicolaas Duneas Osteoinductive biomaterials
AU2004272072B2 (en) 2003-09-12 2010-07-08 Etex Corporation Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
CA2535169A1 (en) 2003-12-31 2005-07-21 Osteotech, Inc. Improved bone matrix compositions and methods
US8734525B2 (en) 2003-12-31 2014-05-27 Warsaw Orthopedic, Inc. Osteoinductive demineralized cancellous bone
EP1771470B1 (en) 2004-07-23 2013-06-26 Acceleron Pharma Inc. Actrii receptor polypeptides, methods and compositions
CN101365499A (zh) 2005-11-01 2009-02-11 骨骼技术股份有限公司 骨基质组合物和方法
TW201803890A (zh) 2007-02-02 2018-02-01 艾瑟勒朗法瑪公司 衍生自ＡｃｔＲＩＩＢ的變體與其用途
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
CA2690457C (en) 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
CA2690816C (en) 2007-06-15 2016-12-06 Osteotech, Inc. Method of treating tissue
WO2009009684A1 (en) 2007-07-10 2009-01-15 Osteotech, Inc. Delivery system
US8202539B2 (en) 2007-10-19 2012-06-19 Warsaw Orthopedic, Inc. Demineralized bone matrix compositions and methods
US9101475B2 (en) 2009-02-12 2015-08-11 Warsaw Orthopedic, Inc. Segmented delivery system
AU2010322011B2 (en) 2009-11-17 2016-03-31 Acceleron Pharma Inc. ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
JP7280182B2 (ja) 2016-10-05 2023-05-23 アクセルロン ファーマ インコーポレイテッド バリアントＡｃｔＲＩＩＢタンパク質およびその使用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4113385A (en) * 1984-03-20 1985-10-11 Caplan, Arnold I. Bone protein purification process

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4113385A (en) * 1984-03-20 1985-10-11 Caplan, Arnold I. Bone protein purification process

Also Published As

Publication number Publication date
EP0148155A2 (en) 1985-07-10
IE57966B1 (en) 1993-06-02
NZ210699A (en) 1989-06-28
DK2285A (da) 1985-07-05
CA1241641A (en) 1988-09-06
DE3569542D1 (en) 1989-05-24
JPS60226814A (ja) 1985-11-12
IE850010L (en) 1985-07-04
EP0148155A3 (en) 1986-08-13
DK161524C (da) 1991-12-23
AU3722184A (en) 1985-07-11
ATE42309T1 (de) 1989-05-15
DK161524B (da) 1991-07-15
GR850006B (forum.php) 1985-05-03
ZA8547B (en) 1986-09-24
EP0148155B1 (en) 1989-04-19
DK2285D0 (da) 1985-01-02

Similar Documents

Publication Publication Date Title
AU580975B2 (en) Osteogenic factors
HUT51279A (en) Process for producing 2-phosphate-esters of ascorbinic acid and pharmaceutical compositions containing them as active components
HUT46710A (en) Process for producing peptode derivatives and pharmaceutical compositions containing them as active components
HUT47274A (en) Process for producing terciary hydroxy-alkyl-xantines and pharmaceutical compositions containing them as active components
HUT45695A (en) Compositions for determining growth of plants and process for producing 5-acylamino-pyrazol derivatives as active components
HUT45252A (en) Process for producing imidazo-pyridine derivatives and pharmaceutical compositions containing them as active components
AU7061687A (en) Pharmaceutical composition for treating periodontal diseases
AU590403B2 (en) Pharmaceutical composition for the treatment of periodontal diseases
PL275089A1 (en) Method of obtaining novel pharmaceutical compositions
AU5287090A (en) Method and composition for treatment of periodontal disease
HUT37781A (en) Process for producing 1-fluorphenyl-butyl-4-/2-pirimidinyl/-piperazine derivatives and pharmaceutical compositions containing them as active agents
HUT48247A (en) Process for producing aza-bicyclo-octyl-ether derivatives and pharmaceutical compositions containing them as active components
EP0261336A3 (en) Process for the preparation of pure enantiomers of r-(+)-alpha-lipoic acid and s-(-)-alpha-lipoic acid (thioctic acid), and nonene or mesyl derivatives as intermediates therefor
EP0293751A3 (en) Taurohyodeoxycholic acid for the therapy of calculosis of the biliary tract and of biliary dyspepsia
HUT46930A (en) Process for producing aminoglycoside-steroides and pharmaceutical compositions containing them as active components
AU6142786A (en) Novel correction compositions and process for using same
JO1589B1 (en) Ketones (quaternary hydroimidazo (4.1) benzo-diazepine-2) anti-viral
HUT45540A (en) Process for producing beta-lactame compounds and pharmaceutical compositions containing them as active componenets
HUT46837A (en) Compositions of insectifuge and acarifuge activity containing alpha, omega-amino-alkohol derivatives as active components and process for producing the active components
GB8816096D0 (en) New method & compositions of matter
HUT47210A (en) Insecticide compositions and process for producing benzoyl-urea derivatives as active components
HUT39437A (en) Process for producing new morpholinol derivatives and pharmaceutical compositions containing them as active agents
AU7448487A (en) Pharmaceutical composition for protection of brain cells
AU2799989A (en) Method of preparation of inoculum sections for plant tissue culture
AU7720487A (en) Pharmaceutical composition for protection of brain cells