DK2285D0 - Osteogen faktor og middel indeholdende denne faktor - Google Patents

Osteogen faktor og middel indeholdende denne faktor

Info

Publication number
DK2285D0
DK2285D0 DK2285A DK2285A DK2285D0 DK 2285 D0 DK2285 D0 DK 2285D0 DK 2285 A DK2285 A DK 2285A DK 2285 A DK2285 A DK 2285A DK 2285 D0 DK2285 D0 DK 2285D0
Authority
DK
Denmark
Prior art keywords
factor
protein
esteogen
medium containing
bone
Prior art date
Application number
DK2285A
Other languages
English (en)
Other versions
DK2285A (da
DK161524B (da
DK161524C (da
Inventor
Arup Sen
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of DK2285D0 publication Critical patent/DK2285D0/da
Publication of DK2285A publication Critical patent/DK2285A/da
Publication of DK161524B publication Critical patent/DK161524B/da
Application granted granted Critical
Publication of DK161524C publication Critical patent/DK161524C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Magnetic Heads (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK002285A 1984-01-04 1985-01-02 Fremgangsmaade til isolering af et praeparat af et osteogent protein samt et praeparat i stand til at fremme osteogenese fremstillet ved fremgangsmaaden DK161524C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56816784A 1984-01-04 1984-01-04
US56816784 1984-01-04

Publications (4)

Publication Number Publication Date
DK2285D0 true DK2285D0 (da) 1985-01-02
DK2285A DK2285A (da) 1985-07-05
DK161524B DK161524B (da) 1991-07-15
DK161524C DK161524C (da) 1991-12-23

Family

ID=24270176

Family Applications (1)

Application Number Title Priority Date Filing Date
DK002285A DK161524C (da) 1984-01-04 1985-01-02 Fremgangsmaade til isolering af et praeparat af et osteogent protein samt et praeparat i stand til at fremme osteogenese fremstillet ved fremgangsmaaden

Country Status (11)

Country Link
EP (1) EP0148155B1 (da)
JP (1) JPS60226814A (da)
AT (1) ATE42309T1 (da)
AU (1) AU580975B2 (da)
CA (1) CA1241641A (da)
DE (1) DE3569542D1 (da)
DK (1) DK161524C (da)
GR (1) GR850006B (da)
IE (1) IE57966B1 (da)
NZ (1) NZ210699A (da)
ZA (1) ZA8547B (da)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
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US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
US4627982A (en) * 1984-07-16 1986-12-09 Collagen Corporation Partially purified bone-inducing factor
JPH0723322B2 (ja) * 1985-12-07 1995-03-15 克之 藤井 液状骨形成剤からなる注射液
US6432919B1 (en) 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
US4877864A (en) * 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
IL83003A (en) 1986-07-01 1995-07-31 Genetics Inst Osteoinductive factors
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
DE3626414C2 (de) * 1986-08-05 1994-11-10 Robapharm Ag Präparat zur Stimulierung von Chondrocyten und Osteoblasten (Ossein-Hydroxyapatit-Komplex), Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
EP0271668B1 (de) * 1986-10-22 1991-12-18 Gesellschaft für Biotechnologische Forschung mbH (GBF) Wachstumstimulierendes Material, Herstellungsverfahren und therapeutische Zusammensetzung
EP0336760A3 (en) * 1988-04-06 1991-03-13 Celtrix Pharmaceuticals, Inc. Bone-inducing protein
US5258494A (en) 1988-04-08 1993-11-02 Stryker Corporation Osteogenic proteins
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5108753A (en) * 1988-04-08 1992-04-28 Creative Biomolecules Osteogenic devices
US6919308B2 (en) 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US5324819A (en) * 1988-04-08 1994-06-28 Stryker Corporation Osteogenic proteins
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5670336A (en) * 1988-04-08 1997-09-23 Stryker Corporation Method for recombinant production of osteogenic protein
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5162114A (en) * 1989-02-23 1992-11-10 Stryker Corporation Bone collagen matrix for xenogenic implants
US5250302A (en) * 1988-04-08 1993-10-05 Stryker Corporation Osteogenic devices
US4968590A (en) * 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
CA1338663C (en) * 1988-04-08 1996-10-22 Hermann Oppermann Biosynthetic osteogenic proteins and osteogenic devices containing them
IL90683A0 (en) * 1988-06-27 1990-01-18 Yissum Res Dev Co Osteogenic growth factors derived from regenerating bone marrow
US5106626A (en) * 1988-10-11 1992-04-21 International Genetic Engineering, Inc. Osteogenic factors
JPH03151877A (ja) * 1989-06-02 1991-06-28 Chiron Corp 骨カルシウム沈着因子
CA2020729A1 (en) * 1989-07-19 1991-01-20 Michael C. Kiefer Bone morphogenetic protein
WO1991005802A1 (en) * 1989-10-17 1991-05-02 Creative Biomolecules, Inc. Osteogenic devices
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US7056882B2 (en) 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5652337A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. OP-3-induced morphogenesis
US5972884A (en) * 1991-03-11 1999-10-26 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US6495513B1 (en) 1991-03-11 2002-12-17 Curis, Inc. Morphogen-enhanced survival and repair of neural cells
US5739107A (en) * 1991-03-11 1998-04-14 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US5656593A (en) * 1991-03-11 1997-08-12 Creative Biomolecules, Inc. Morphogen induced periodontal tissue regeneration
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US5849686A (en) * 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US6800603B2 (en) 1991-03-11 2004-10-05 Curis, Inc. Morphogen-induced neural cell adhesion
CA2363965C (en) 1991-03-11 2010-05-18 Curis, Inc. Protein-induced morphogenesis
US6949505B1 (en) 1991-03-11 2005-09-27 Curis, Inc. Morphogen-induced dendritic growth
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
US6022853A (en) * 1991-08-30 2000-02-08 Creative Biomolecules, Inc. Morphogen-enriched dietary composition
EP0612348B1 (en) 1991-11-04 2003-04-23 Genetics Institute, LLC Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
ATE258984T1 (de) 1993-05-12 2004-02-15 Inst Genetics Llc Bmp-11 zusammensetzungen
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
EP0733109B9 (en) 1993-12-07 2006-07-05 Genetics Institute, LLC Bmp-12, bmp-13 and tendon-inducing compositions thereof
US5928940A (en) * 1996-09-24 1999-07-27 Creative Biomolecules, Inc. Morphogen-responsive signal transducer and methods of use thereof
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
TWI329129B (en) 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
DE60332848D1 (de) 2002-06-20 2010-07-15 Altis Biolog Pty Ltd Osteoinduktive biomaterialien
ATE357244T1 (de) 2003-09-12 2007-04-15 Wyeth Corp Injizierbare feste calciumphosphat-stäbe zur abgabe von osteogenen proteinen
US8328876B2 (en) 2003-12-31 2012-12-11 Warsaw Orthopedic, Inc. Bone matrix compositions and methods
EP2314617B1 (en) 2004-07-23 2015-06-24 Acceleron Pharma Inc. ActRII receptor polypeptides
ES2393756T3 (es) 2005-11-01 2012-12-27 Warsaw Orthopedic, Inc. Métodos para producir composiciones de matriz ósea
TW202104248A (zh) 2007-02-02 2021-02-01 美商艾瑟勒朗法瑪公司 衍生自ActRIIB的變體與其用途
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
EP2167147B1 (en) 2007-06-15 2017-03-29 Warsaw Orthopedic, Inc. Bone matrix compositions and methods
WO2008157492A2 (en) 2007-06-15 2008-12-24 Osteotech, Inc. Osteoinductive demineralized cancellous bone
EP2167148B1 (en) 2007-06-15 2017-12-27 Warsaw Orthopedic, Inc. Method of treating tissue
WO2009009688A1 (en) 2007-07-10 2009-01-15 Osteotech, Inc. Delivery system
ES2446544T3 (es) 2007-10-19 2014-03-10 Warsaw Orthopedic, Inc. Composiciones de matrices óseas desmineralizadas y métodos
WO2010093959A2 (en) 2009-02-12 2010-08-19 Osteotech, Inc. Delivery systems, tools, and methods of use
US8710016B2 (en) 2009-11-17 2014-04-29 Acceleron Pharma, Inc. ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
CN110036025B (zh) 2016-10-05 2024-03-22 阿塞勒隆制药公司 变体ActRIIB蛋白及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process
US4608199A (en) * 1984-03-20 1986-08-26 Arnold Caplan Bone protein purification process

Also Published As

Publication number Publication date
JPS60226814A (ja) 1985-11-12
DK2285A (da) 1985-07-05
EP0148155A3 (en) 1986-08-13
EP0148155B1 (en) 1989-04-19
ZA8547B (en) 1986-09-24
DE3569542D1 (en) 1989-05-24
IE850010L (en) 1985-07-04
DK161524B (da) 1991-07-15
ATE42309T1 (de) 1989-05-15
AU580975B2 (en) 1989-02-09
DK161524C (da) 1991-12-23
GR850006B (da) 1985-05-03
NZ210699A (en) 1989-06-28
IE57966B1 (en) 1993-06-02
CA1241641A (en) 1988-09-06
EP0148155A2 (en) 1985-07-10
AU3722184A (en) 1985-07-11

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