AU5784499A - Methods and compositions employing optically pure s(+) vigabatrin - Google Patents
Methods and compositions employing optically pure s(+) vigabatrin Download PDFInfo
- Publication number
- AU5784499A AU5784499A AU57844/99A AU5784499A AU5784499A AU 5784499 A AU5784499 A AU 5784499A AU 57844/99 A AU57844/99 A AU 57844/99A AU 5784499 A AU5784499 A AU 5784499A AU 5784499 A AU5784499 A AU 5784499A
- Authority
- AU
- Australia
- Prior art keywords
- vigabatrin
- administered
- pharmaceutically acceptable
- acceptable salt
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229960002911 zonisamide Drugs 0.000 description 1
- UBQNRHZMVUUOMG-UHFFFAOYSA-N zonisamide Chemical compound C1=CC=C2C(CS(=O)(=O)N)=NOC2=C1 UBQNRHZMVUUOMG-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9778698P | 1998-08-25 | 1998-08-25 | |
| US60097786 | 1998-08-25 | ||
| US11445698P | 1998-12-30 | 1998-12-30 | |
| US60114456 | 1998-12-30 | ||
| PCT/US1999/019346 WO2000010554A2 (fr) | 1998-08-25 | 1999-08-24 | Procedes et compositions employant le vigabatrin s(+) optiquement pur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU5784499A true AU5784499A (en) | 2000-03-14 |
Family
ID=26793638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU57844/99A Abandoned AU5784499A (en) | 1998-08-25 | 1999-08-24 | Methods and compositions employing optically pure s(+) vigabatrin |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1107748A2 (fr) |
| JP (1) | JP2003520189A (fr) |
| AU (1) | AU5784499A (fr) |
| CA (1) | CA2341400A1 (fr) |
| WO (1) | WO2000010554A2 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007136845A2 (fr) | 2006-05-19 | 2007-11-29 | Somaxon Pharmaceuticals, Inc. | Doxépine à faible dose utilisée pour le traitement de troubles du sommeil chez des patients âgés |
| US20100179214A1 (en) | 2006-05-19 | 2010-07-15 | Somaxon Pharmaceuticals, Inc. | Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders |
| CA2687118A1 (fr) | 2006-05-19 | 2007-12-13 | Somaxon Pharmaceuticals, Inc. | Procedes d'utilisation de doxepine faiblement dosee pour ameliorer le sommeil |
| US20100179215A1 (en) | 2006-05-19 | 2010-07-15 | Somaxon Pharmaceuticals, Inc. | Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders |
| WO2008011150A1 (fr) | 2006-07-20 | 2008-01-24 | Somaxon Pharmaceuticals, Inc. | Méthodes destinées à améliorer la pharmacocinétique de la doxépine |
| WO2008052139A2 (fr) | 2006-10-25 | 2008-05-02 | Somaxon Pharmaceuticals, Inc. | Doxepine à dose ultrafaible, et ses procédés d'utilisation pour traiter des troubles du sommeil |
| US20110077200A1 (en) | 2006-12-06 | 2011-03-31 | Somaxon Pharmaceuticals, Inc. | Combination therapy using low-dose doxepin for the improvement of sleep |
| EP2148659A2 (fr) | 2007-04-13 | 2010-02-03 | Somaxon Pharmaceuticals, Inc. | Formulations de doxépine à faible dose et procédé de préparation et d'utilisation de celle-ci |
| CA3016851A1 (fr) * | 2016-03-10 | 2017-09-14 | Orphelia Pharma | Formes galeniques solides de vigabatrine |
| CN110869003A (zh) * | 2019-01-28 | 2020-03-06 | 上海奥科达生物医药科技有限公司 | 一种不含防腐剂的固体剂型氨己烯酸药物组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2133002B (en) * | 1982-12-30 | 1986-01-29 | Merrell Toraude & Co | Process for preparing 4-amino-5-hexenoic acid |
| US4595697A (en) * | 1984-03-28 | 1986-06-17 | Merrell Dow Pharmaceuticals Inc. | Treatment of seizure disorders and pharmaceutical compositions useful therein |
| EP0509180A1 (fr) * | 1991-04-18 | 1992-10-21 | Merrell Dow Pharmaceuticals Inc. | Utilisation d'inhibiteurs de la GABA-T pour le traitement de la schizophrenie et l'intoxication de la phencyclidine |
| US6541520B1 (en) * | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
-
1999
- 1999-08-24 EP EP99945177A patent/EP1107748A2/fr not_active Withdrawn
- 1999-08-24 CA CA002341400A patent/CA2341400A1/fr not_active Abandoned
- 1999-08-24 JP JP2000565876A patent/JP2003520189A/ja active Pending
- 1999-08-24 WO PCT/US1999/019346 patent/WO2000010554A2/fr not_active Application Discontinuation
- 1999-08-24 AU AU57844/99A patent/AU5784499A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000010554A2 (fr) | 2000-03-02 |
| WO2000010554A3 (fr) | 2000-11-30 |
| JP2003520189A (ja) | 2003-07-02 |
| EP1107748A2 (fr) | 2001-06-20 |
| CA2341400A1 (fr) | 2000-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |