AU556058B2 - Anti-diarrhoeal benzothiophene derivatives - Google Patents
Anti-diarrhoeal benzothiophene derivativesInfo
- Publication number
- AU556058B2 AU556058B2 AU44713/85A AU4471385A AU556058B2 AU 556058 B2 AU556058 B2 AU 556058B2 AU 44713/85 A AU44713/85 A AU 44713/85A AU 4471385 A AU4471385 A AU 4471385A AU 556058 B2 AU556058 B2 AU 556058B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- compounds
- formula
- mixture
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Organic Insulating Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8417559 | 1984-07-10 | ||
| GB848417559A GB8417559D0 (en) | 1984-07-10 | 1984-07-10 | Anti-diarrhoeal agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4471385A AU4471385A (en) | 1986-01-16 |
| AU556058B2 true AU556058B2 (en) | 1986-10-23 |
Family
ID=10563672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU44713/85A Ceased AU556058B2 (en) | 1984-07-10 | 1985-07-09 | Anti-diarrhoeal benzothiophene derivatives |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4654352A (enExample) |
| EP (1) | EP0169012A1 (enExample) |
| JP (1) | JPS6136281A (enExample) |
| KR (1) | KR860001094A (enExample) |
| CN (1) | CN85105193A (enExample) |
| AU (1) | AU556058B2 (enExample) |
| CS (1) | CS249545B2 (enExample) |
| DD (1) | DD238792A5 (enExample) |
| DK (1) | DK312485A (enExample) |
| ES (1) | ES8604557A1 (enExample) |
| FI (1) | FI852691A7 (enExample) |
| GB (1) | GB8417559D0 (enExample) |
| GR (1) | GR851688B (enExample) |
| HU (1) | HUT38330A (enExample) |
| IL (1) | IL75740A0 (enExample) |
| NO (1) | NO852760L (enExample) |
| PL (1) | PL254445A1 (enExample) |
| PT (1) | PT80786B (enExample) |
| YU (1) | YU113985A (enExample) |
| ZA (1) | ZA855153B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4128690A1 (de) * | 1991-08-29 | 1993-03-04 | Boehringer Mannheim Gmbh | Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| DE69525763T2 (de) * | 1994-04-11 | 2002-10-02 | Chugai Seiyaku K.K., Tokio/Tokyo | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENE, DIE LDL OXIDATION HEMMEN |
| CA2207141A1 (en) * | 1996-07-15 | 1998-01-15 | David Thompson Berg | Benzothiophene compounds, and uses and formulations thereof |
| CA2207083A1 (en) * | 1996-07-15 | 1998-01-15 | Brian William Grinnell | Benzothiophene compounds, and uses and formulations thereof |
| US5792798A (en) * | 1996-07-29 | 1998-08-11 | Eli Lilly And Company | Method for inhibiting plasminogen activator inhibitor 1 |
| CN1251577A (zh) * | 1997-02-21 | 2000-04-26 | 武田药品工业株式会社 | 稠环化合物及其生产和应用 |
| HRP20000767A2 (en) * | 1998-05-12 | 2001-10-31 | American Home Prod | Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia |
| US6251936B1 (en) | 1998-05-12 | 2001-06-26 | American Home Products Corporation | Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia |
| PT1334094E (pt) * | 2000-11-02 | 2005-05-31 | Hoffmann La Roche | Benzo[b]tiofenos e benzo(d)isotiazoles para diminuir o colesterol |
| US6969730B2 (en) | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
| WO2006019497A2 (en) * | 2004-06-17 | 2006-02-23 | Neurocrine Biosciences, Inc. | Sleep-inducing compounds and methods related thereto |
| JP5180807B2 (ja) | 2008-12-24 | 2013-04-10 | 三菱重工業株式会社 | １段静翼の冷却構造、及びガスタービン |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1174411A (en) * | 1966-03-02 | 1969-12-17 | Aspro Nicholas Ltd | Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture |
| US3598839A (en) * | 1969-06-30 | 1971-08-10 | Parke Davis & Co | Phenylbenzothiophene compounds |
| US3944672A (en) * | 1972-12-13 | 1976-03-16 | Schering Corporation | Method for treating microbial infections |
| NL7506021A (nl) * | 1974-05-28 | 1975-12-02 | Scherico Ltd | Antimicrobiele verbindingen. |
| US4018893A (en) * | 1974-05-28 | 1977-04-19 | Schering Corporation | Methods for treating microbial infections |
| US4137414A (en) * | 1977-09-26 | 1979-01-30 | G. D. Searle & Co. | 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds |
-
1984
- 1984-07-10 GB GB848417559A patent/GB8417559D0/en active Pending
-
1985
- 1985-06-28 US US06/750,115 patent/US4654352A/en not_active Expired - Lifetime
- 1985-07-05 EP EP85304793A patent/EP0169012A1/en not_active Withdrawn
- 1985-07-08 PL PL25444585A patent/PL254445A1/xx unknown
- 1985-07-08 GR GR851688A patent/GR851688B/el unknown
- 1985-07-08 CN CN198585105193A patent/CN85105193A/zh active Pending
- 1985-07-08 PT PT80786A patent/PT80786B/pt unknown
- 1985-07-08 FI FI852691A patent/FI852691A7/fi not_active Application Discontinuation
- 1985-07-08 ES ES544970A patent/ES8604557A1/es not_active Expired
- 1985-07-08 IL IL75740A patent/IL75740A0/xx unknown
- 1985-07-08 CS CS855105A patent/CS249545B2/cs unknown
- 1985-07-09 DD DD85278412A patent/DD238792A5/de unknown
- 1985-07-09 KR KR1019850004875A patent/KR860001094A/ko not_active Ceased
- 1985-07-09 AU AU44713/85A patent/AU556058B2/en not_active Ceased
- 1985-07-09 NO NO852760A patent/NO852760L/no unknown
- 1985-07-09 DK DK312485A patent/DK312485A/da not_active Application Discontinuation
- 1985-07-09 ZA ZA855153A patent/ZA855153B/xx unknown
- 1985-07-09 JP JP15117785A patent/JPS6136281A/ja active Pending
- 1985-07-09 YU YU01139/85A patent/YU113985A/xx unknown
- 1985-07-09 HU HU852658A patent/HUT38330A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK312485A (da) | 1986-01-11 |
| GR851688B (enExample) | 1985-11-26 |
| ZA855153B (en) | 1987-02-25 |
| PL254445A1 (en) | 1986-07-15 |
| US4654352A (en) | 1987-03-31 |
| YU113985A (en) | 1987-08-31 |
| FI852691L (fi) | 1986-01-11 |
| GB8417559D0 (en) | 1984-08-15 |
| EP0169012A1 (en) | 1986-01-22 |
| DK312485D0 (da) | 1985-07-09 |
| PT80786B (en) | 1987-03-26 |
| FI852691A0 (fi) | 1985-07-08 |
| CN85105193A (zh) | 1987-01-28 |
| PT80786A (en) | 1985-08-01 |
| KR860001094A (ko) | 1986-02-22 |
| ES544970A0 (es) | 1986-02-01 |
| DD238792A5 (de) | 1986-09-03 |
| NO852760L (no) | 1986-01-13 |
| ES8604557A1 (es) | 1986-02-01 |
| IL75740A0 (en) | 1985-11-29 |
| FI852691A7 (fi) | 1986-01-11 |
| AU4471385A (en) | 1986-01-16 |
| CS249545B2 (en) | 1987-03-12 |
| HUT38330A (en) | 1986-05-28 |
| JPS6136281A (ja) | 1986-02-20 |
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