AU554856B2 - Imidazo(1,2- )quinoline derivatives with anxiolytic activity - Google Patents
Imidazo(1,2- )quinoline derivatives with anxiolytic activityInfo
- Publication number
- AU554856B2 AU554856B2 AU82314/82A AU8231482A AU554856B2 AU 554856 B2 AU554856 B2 AU 554856B2 AU 82314/82 A AU82314/82 A AU 82314/82A AU 8231482 A AU8231482 A AU 8231482A AU 554856 B2 AU554856 B2 AU 554856B2
- Authority
- AU
- Australia
- Prior art keywords
- carbon atoms
- group
- alkoxy
- alkyl
- imidazo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000000949 anxiolytic effect Effects 0.000 title abstract 2
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- HJMONQQZFQKQPS-UHFFFAOYSA-N imidazo[1,2-a]quinoline Chemical class C1=CC=C2N3C=CN=C3C=CC2=C1 HJMONQQZFQKQPS-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Sorption Type Refrigeration Machines (AREA)
- Soil Conditioners And Soil-Stabilizing Materials (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8110586 | 1981-04-03 | ||
| GB8110586 | 1981-04-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU8231482A AU8231482A (en) | 1982-10-07 |
| AU554856B2 true AU554856B2 (en) | 1986-09-04 |
Family
ID=10520927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU82314/82A Ceased AU554856B2 (en) | 1981-04-03 | 1982-04-02 | Imidazo(1,2- )quinoline derivatives with anxiolytic activity |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4387098A (en, 2012) |
| EP (1) | EP0062580B1 (en, 2012) |
| JP (1) | JPS57176986A (en, 2012) |
| KR (1) | KR880001738B1 (en, 2012) |
| AT (1) | ATE16389T1 (en, 2012) |
| AU (1) | AU554856B2 (en, 2012) |
| CA (1) | CA1175428A (en, 2012) |
| DE (1) | DE3267238D1 (en, 2012) |
| DK (1) | DK156572C (en, 2012) |
| EG (1) | EG15805A (en, 2012) |
| ES (1) | ES510483A0 (en, 2012) |
| FI (1) | FI75568C (en, 2012) |
| GB (1) | GB2096143B (en, 2012) |
| GR (1) | GR76063B (en, 2012) |
| HU (1) | HU189129B (en, 2012) |
| IE (1) | IE52873B1 (en, 2012) |
| IL (1) | IL65140A (en, 2012) |
| MA (1) | MA19434A1 (en, 2012) |
| MX (1) | MX7118E (en, 2012) |
| NO (1) | NO157578C (en, 2012) |
| NZ (1) | NZ200218A (en, 2012) |
| PH (1) | PH17858A (en, 2012) |
| PT (1) | PT74699B (en, 2012) |
| ZA (1) | ZA821407B (en, 2012) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA836701B (en) * | 1982-10-01 | 1984-10-31 | Roussel Uclaf | Imidazo(1,2-a)quinolines |
| US4675323A (en) * | 1985-08-06 | 1987-06-23 | Synthelabo | Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents |
| GB8620060D0 (en) * | 1986-08-18 | 1986-10-01 | Roussel Lab Ltd | Chemical compounds |
| FR2624861B1 (fr) * | 1987-12-21 | 1990-06-01 | Delalande Sa | Carbamates tricycliques, leur procede de preparation et leur application en therapeutique |
| HUP0105406A3 (en) * | 2001-12-21 | 2003-12-29 | Sanofi Aventis | Imidazo[1,2-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates |
| HUP0700395A2 (en) * | 2007-06-07 | 2009-03-02 | Sanofi Aventis | Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates |
| BR112023001551A2 (pt) * | 2020-08-17 | 2023-02-28 | Lmito Therapeutics Inc | Composto de imidazoquinolina ou benzoindazolona e intermediário para preparar o mesmo |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1596652A (en) * | 1977-01-20 | 1981-08-26 | Roussel Lab Ltd | Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives |
-
1981
- 1981-03-31 GR GR67771A patent/GR76063B/el unknown
-
1982
- 1982-03-01 IL IL65140A patent/IL65140A/xx unknown
- 1982-03-03 ZA ZA821407A patent/ZA821407B/xx unknown
- 1982-03-16 ES ES510483A patent/ES510483A0/es active Granted
- 1982-03-22 KR KR8201210A patent/KR880001738B1/ko not_active Expired
- 1982-03-25 US US06/361,779 patent/US4387098A/en not_active Expired - Fee Related
- 1982-03-29 PH PH27075A patent/PH17858A/en unknown
- 1982-03-29 EG EG168/82A patent/EG15805A/xx active
- 1982-03-30 MX MX8210010U patent/MX7118E/es unknown
- 1982-03-31 DE DE8282400590T patent/DE3267238D1/de not_active Expired
- 1982-03-31 EP EP82400590A patent/EP0062580B1/fr not_active Expired
- 1982-03-31 CA CA000400184A patent/CA1175428A/en not_active Expired
- 1982-03-31 AT AT82400590T patent/ATE16389T1/de active
- 1982-04-02 PT PT74699A patent/PT74699B/pt unknown
- 1982-04-02 AU AU82314/82A patent/AU554856B2/en not_active Ceased
- 1982-04-02 FI FI821171A patent/FI75568C/fi not_active IP Right Cessation
- 1982-04-02 GB GB8209850A patent/GB2096143B/en not_active Expired
- 1982-04-02 NZ NZ200218A patent/NZ200218A/en unknown
- 1982-04-02 NO NO821118A patent/NO157578C/no unknown
- 1982-04-02 DK DK150782A patent/DK156572C/da not_active IP Right Cessation
- 1982-04-02 IE IE780/82A patent/IE52873B1/en unknown
- 1982-04-02 JP JP57053960A patent/JPS57176986A/ja active Pending
- 1982-04-02 HU HU821022A patent/HU189129B/hu not_active IP Right Cessation
- 1982-04-02 MA MA19638A patent/MA19434A1/fr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE44879L (en) | Quinoline derivatives | |
| ES8802521A1 (es) | Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas | |
| IL88303A (en) | Derivatives of 6-fluoro-7-û4-( (5-methyl-2-oxo-1,3- dioxolen-4-yl)methyl) piperazin-1-ylù-4 (1h)-oxo-1,3-thiazeto(3,2-a) quinoline-3-carboxylic acid | |
| AU591640B2 (en) | Quinolonecarboxylic acid derivatives | |
| ES8304567A1 (es) | "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida". | |
| DE3273377D1 (en) | Pyrimido quinoxalines and their salts, their preparation, their use as medicaments and compositions containing them | |
| AU554856B2 (en) | Imidazo(1,2- )quinoline derivatives with anxiolytic activity | |
| AU588366B2 (en) | Pyrido (1,2-a) pyrimidine derivatives, processes for preparing the same and pharmaceutical compositions for the treatment of allergic diseases containing the same | |
| AU584988B2 (en) | New 8-thiotetrahydroquinoline derivatives and salts thereof | |
| AU584777B2 (en) | 1-(acylaminomethyl) imidazo ``1,2-a`` quinoline derivatives their preparation and their application in therapy | |
| GB2192000B (en) | Tetrahydroquinoline compounds | |
| GB2071093B (en) | Benzothiopyrano(2,3-c)pyridines | |
| ES8307812A1 (es) | Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo. |