AU533213B2 - Liposomes as vehicles for therapeutic and diagnostic substances - Google Patents

Liposomes as vehicles for therapeutic and diagnostic substances

Info

Publication number
AU533213B2
AU533213B2 AU64203/80A AU6420380A AU533213B2 AU 533213 B2 AU533213 B2 AU 533213B2 AU 64203/80 A AU64203/80 A AU 64203/80A AU 6420380 A AU6420380 A AU 6420380A AU 533213 B2 AU533213 B2 AU 533213B2
Authority
AU
Australia
Prior art keywords
cholesten
yloxy
thio
hexyl
vesicles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU64203/80A
Other languages
English (en)
Other versions
AU6420380A (en
Inventor
John D. Baldeschwieler
Ronald Carl Gamble
Marcia R. Mauk
Mitree M. Ponpipom
Tsung-Ying Shen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
California Institute of Technology
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology, Merck and Co Inc filed Critical California Institute of Technology
Publication of AU6420380A publication Critical patent/AU6420380A/en
Application granted granted Critical
Publication of AU533213B2 publication Critical patent/AU533213B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU64203/80A 1979-11-08 1980-11-07 Liposomes as vehicles for therapeutic and diagnostic substances Ceased AU533213B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/092,342 US4310505A (en) 1979-11-08 1979-11-08 Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
US92342 1979-11-08

Publications (2)

Publication Number Publication Date
AU6420380A AU6420380A (en) 1981-05-14
AU533213B2 true AU533213B2 (en) 1983-11-10

Family

ID=22232767

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64203/80A Ceased AU533213B2 (en) 1979-11-08 1980-11-07 Liposomes as vehicles for therapeutic and diagnostic substances

Country Status (12)

Country Link
US (1) US4310505A (en:Method)
EP (1) EP0028917B1 (en:Method)
JP (1) JPS5675439A (en:Method)
AT (1) ATE7656T1 (en:Method)
AU (1) AU533213B2 (en:Method)
DE (1) DE3068062D1 (en:Method)
DK (1) DK154264C (en:Method)
ES (1) ES8203222A1 (en:Method)
GR (1) GR71720B (en:Method)
IE (1) IE50369B1 (en:Method)
NZ (1) NZ195377A (en:Method)
PT (1) PT72040B (en:Method)

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US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
US3992513A (en) * 1975-01-07 1976-11-16 Atomic Energy Of Canada Limited Labelled phospholipid material colloidially dispersed and sized to localize at preselected organs
DE2656333C2 (de) * 1976-12-13 1985-08-08 Karl Prof. Dr.med. 7302 Ostfildern Theurer Verfahren zur Herstellung von Liposomen, welche Arzneistoffe enthalten
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith

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JPS647966B2 (en:Method) 1989-02-10
DE3068062D1 (en) 1984-07-05
DK154264C (da) 1989-03-28
IE50369B1 (en) 1986-04-02
ES496666A0 (es) 1982-04-01
JPS5675439A (en) 1981-06-22
IE802286L (en) 1981-05-08
AU6420380A (en) 1981-05-14
PT72040B (en) 1982-09-02
GR71720B (en:Method) 1983-06-21
EP0028917B1 (en) 1984-05-30
DK154264B (da) 1988-10-31
EP0028917A3 (en) 1981-07-15
NZ195377A (en) 1984-07-06
ATE7656T1 (de) 1984-06-15
EP0028917A2 (en) 1981-05-20
ES8203222A1 (es) 1982-04-01
PT72040A (en) 1980-12-01
DK472980A (da) 1981-05-09
US4310505A (en) 1982-01-12

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