AU525142B2 - 3-(2-acetamidoethylithio)- and 3-(2-acetamidoethenylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylic acid - Google Patents

3-(2-acetamidoethylithio)- and 3-(2-acetamidoethenylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylic acid

Info

Publication number
AU525142B2
AU525142B2 AU33841/78A AU3384178A AU525142B2 AU 525142 B2 AU525142 B2 AU 525142B2 AU 33841/78 A AU33841/78 A AU 33841/78A AU 3384178 A AU3384178 A AU 3384178A AU 525142 B2 AU525142 B2 AU 525142B2
Authority
AU
Australia
Prior art keywords
acetamidoethylithio
acetamidoethenylthio
azabicyclo
hept
ene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU33841/78A
Other languages
English (en)
Other versions
AU3384178A (en
Inventor
John Box Stephen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9366/77A external-priority patent/GB1601688A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of AU3384178A publication Critical patent/AU3384178A/en
Application granted granted Critical
Publication of AU525142B2 publication Critical patent/AU525142B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU33841/78A 1977-03-05 1978-03-03 3-(2-acetamidoethylithio)- and 3-(2-acetamidoethenylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylic acid Expired AU525142B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB779366 1977-03-05
GB9366/77A GB1601688A (en) 1977-03-05 1977-03-05 6-(1-hydroxyethyl)-7-oxo 1-aza bicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their use in pharmaceutical compositions
GBGB7732836 1977-08-05
GB3283677 1977-08-05

Publications (2)

Publication Number Publication Date
AU3384178A AU3384178A (en) 1979-09-06
AU525142B2 true AU525142B2 (en) 1982-10-21

Family

ID=26242889

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33841/78A Expired AU525142B2 (en) 1977-03-05 1978-03-03 3-(2-acetamidoethylithio)- and 3-(2-acetamidoethenylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo(3,2,0)hept-2-ene-2-carboxylic acid

Country Status (11)

Country Link
JP (1) JPS53116396A (it)
AU (1) AU525142B2 (it)
CH (1) CH641805A5 (it)
DE (1) DE2808563A1 (it)
DK (1) DK98478A (it)
ES (1) ES467562A1 (it)
FR (1) FR2401162A1 (it)
IE (1) IE46736B1 (it)
IT (1) IT7848280A0 (it)
NL (1) NL7802356A (it)
SE (1) SE7802462L (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
DE2966446D1 (en) * 1978-09-09 1984-01-05 Beecham Group Plc Beta-lactam compounds, their preparation and use
EP0033209B1 (en) * 1980-01-25 1984-06-13 Beecham Group Plc Beta-lactam containing compounds, their preparation and use
IN155384B (it) * 1980-05-14 1985-01-19 Pfizer
JP4977670B2 (ja) * 2008-09-11 2012-07-18 啓司 関口 生花整形器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143713C (da) * 1975-11-21 1982-03-08 Merck & Co Inc Fremgangsmaade til fremstilling af et antibiotisk stof n-acetyl-thienamycin og salte deraf
DK143712C (da) * 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3
NL7704040A (nl) * 1976-04-28 1977-11-01 Merck & Co Inc Werkwijze voor het bereiden van nieuwe anti- biotica.

Also Published As

Publication number Publication date
FR2401162A1 (fr) 1979-03-23
DE2808563A1 (de) 1978-09-07
IT7848280A0 (it) 1978-03-03
SE7802462L (sv) 1978-09-06
JPS53116396A (en) 1978-10-11
AU3384178A (en) 1979-09-06
IE46736B1 (en) 1983-09-07
ES467562A1 (es) 1980-05-16
DK98478A (da) 1978-09-06
CH641805A5 (en) 1984-03-15
IE780443L (en) 1978-09-05
FR2401162B1 (it) 1980-08-29
NL7802356A (nl) 1978-09-07

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