AU517547B2 - Preservation of organs for transplantation - Google Patents

Preservation of organs for transplantation

Info

Publication number
AU517547B2
AU517547B2 AU55002/80A AU5500280A AU517547B2 AU 517547 B2 AU517547 B2 AU 517547B2 AU 55002/80 A AU55002/80 A AU 55002/80A AU 5500280 A AU5500280 A AU 5500280A AU 517547 B2 AU517547 B2 AU 517547B2
Authority
AU
Australia
Prior art keywords
perfusate
transplantation
organs
preservation
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU55002/80A
Other languages
English (en)
Other versions
AU5500280A (en
Inventor
Masakazu Iwai
Hiroyuki Okamoto
Noboru Yamada
Kazumasa Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Publication of AU5500280A publication Critical patent/AU5500280A/en
Application granted granted Critical
Publication of AU517547B2 publication Critical patent/AU517547B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU55002/80A 1978-10-10 1980-01-29 Preservation of organs for transplantation Ceased AU517547B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/950,071 US4186253A (en) 1978-10-10 1978-10-10 Perfusate for preserving organ to be transplanted and preserving method

Publications (2)

Publication Number Publication Date
AU5500280A AU5500280A (en) 1981-07-30
AU517547B2 true AU517547B2 (en) 1981-08-06

Family

ID=25489899

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55002/80A Ceased AU517547B2 (en) 1978-10-10 1980-01-29 Preservation of organs for transplantation

Country Status (6)

Country Link
US (1) US4186253A (https=)
EP (1) EP0033402B1 (https=)
JP (1) JPS5551016A (https=)
AT (1) ATE4572T1 (https=)
AU (1) AU517547B2 (https=)
WO (1) WO1981002103A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0494974A4 (en) * 1989-10-04 1992-09-02 Alliance Pharmaceutical, Inc. Fluorocarbon emulsions containing amino acid based anti-inflammatory agents and buffer systems
WO2002053525A1 (en) * 2000-12-29 2002-07-11 Otkrytoe Aktsionernoe Obschestvo Nauchno-Proizvodstvennaya Firma 'perftoran' Perfluoronated cycle-containing tertiary amines used as a basis for gas-conveying emulsions and device for the production thereof

Families Citing this family (90)

* Cited by examiner, † Cited by third party
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US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
DE3277769D1 (en) * 1981-09-08 1988-01-14 Green Cross Corp Perfluorochemicals, process for preparing the same and their use as blood substitutes
JPS58170782A (ja) * 1982-01-22 1983-10-07 アイ・エス・シ−・ケミカルズ・リミテツド 過弗素化複素環式化合物およびこれを含むエマルシヨン
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
EP0103358B1 (en) * 1982-08-07 1986-10-08 Green Cross Corporation Perfluoro-1-azatricyclic amine compound
JPS5946218A (ja) * 1982-09-09 1984-03-15 Green Cross Corp:The フルオロカ−ボン乳化製剤
DE3586946D1 (de) * 1984-06-22 1993-02-11 Richard L Veech Elektrolytloesungen und deren in-vitro-verwendung.
ATE82500T1 (de) * 1984-06-22 1992-12-15 Richard L Veech Elektrolytloesungen und deren (in vivo) verwendung.
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US4897263A (en) * 1986-05-15 1990-01-30 Emory University Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids
US5089260A (en) * 1986-05-15 1992-02-18 Emory University Method of treating ischemic tissue
US5240701A (en) * 1986-05-15 1993-08-31 Emory University Method of performing angioplasty procedures
US4997644A (en) * 1986-05-15 1991-03-05 Emory University Method of treating adult respiratory distress syndrome
WO1987006836A1 (en) * 1986-05-15 1987-11-19 Emory University Fibrinolytic composition
US5198211A (en) * 1986-05-15 1993-03-30 Emory University Method of treating myocardial damage
US5648071A (en) * 1986-05-15 1997-07-15 Emory University Method of treating tumors
US5039520A (en) * 1986-05-15 1991-08-13 Emory University Plasma extender
US5080894A (en) * 1986-05-15 1992-01-14 Emory University Method and composition for reducing tissue damage
US5017370A (en) * 1986-05-15 1991-05-21 Emory University Improved method of performing angioplasty procedures
US5078995A (en) * 1986-05-15 1992-01-07 Emory University Fibrionolytic composition
US4879109A (en) * 1986-05-15 1989-11-07 Emory University Method for treating burns
US5182106A (en) * 1986-05-15 1993-01-26 Emory University Method for treating hypothermia
US5030448A (en) * 1986-05-15 1991-07-09 Emory University Method of delivering drugs to damaged or diseased tissue
US4801452A (en) * 1986-05-15 1989-01-31 Hunter Robert L Fibrinolytic composition
US4837014A (en) * 1986-05-15 1989-06-06 Emory University An improved method of treating sickle cell anemia
US5047236A (en) * 1986-05-15 1991-09-10 Emory University Method of treating stroke
US5250294A (en) * 1986-05-15 1993-10-05 Emory University Improved perfusion medium for transplantation of organs
US5032394A (en) * 1986-05-15 1991-07-16 Emory University Method of treating burns
US4937070A (en) * 1986-05-15 1990-06-26 Emory University Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids
US5028599A (en) * 1986-05-15 1991-07-02 Emory University Method of treating mycardial damage
US5152979A (en) * 1986-05-15 1992-10-06 Emory University Method for treating vascular obstructions caused by abnormal cells
US5071649A (en) * 1986-05-15 1991-12-10 Emory University Method of preventing blockage in catheters
US5064643A (en) * 1986-05-15 1991-11-12 Emory University Method for treating sickle cell disease
US5041288A (en) * 1986-05-15 1991-08-20 Emory University Method of treating tissue damaged by reperfusion injury
US4873083A (en) * 1986-05-15 1989-10-10 Emory University Fibrinolytic composition
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
JPS63208572A (ja) * 1987-02-24 1988-08-30 Daikin Ind Ltd パ−フルオロ含窒素環状化合物およびその製法
US4873315A (en) * 1987-08-25 1989-10-10 Air Products And Chemicals, Inc. Perfluorinated propyl derivative compounds
US4777304A (en) * 1987-08-25 1988-10-11 Air Products & Chemicals, Inc. Perfluorinated butyl derivative compounds
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
US5073383A (en) * 1989-04-21 1991-12-17 Affinity Biotech, Inc. Inhibiting aggregation in fluorocarbon emulsions
US4938961A (en) * 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia
US5110722A (en) * 1989-11-09 1992-05-05 Cryolife, Inc. Cell, tissue or organ storage solution
US5358931A (en) * 1990-01-17 1994-10-25 The Regents Of The University Of California Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications
AU659795B2 (en) * 1990-01-17 1995-06-01 Regents Of The University Of California, The Composition to improve survival of biological materials
WO1992002133A1 (en) * 1990-08-10 1992-02-20 Analytical Control Systems, Inc. Improved diagnostic and therapeutic compositions
CH683485A5 (fr) * 1990-11-20 1994-03-31 Pasteur Merieux Serums Vacc Solutions de perfusion, de conservation et de reperfusion d'organes.
ES2140408T3 (es) 1991-03-19 2000-03-01 Cytrx Corp Copolimeros de polioxipropileno/polioxietileno con actividad biologica mejorada.
USRE38558E1 (en) 1991-03-19 2004-07-20 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US5696298A (en) * 1991-03-19 1997-12-09 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
US5470568A (en) * 1992-02-13 1995-11-28 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for cell repair
US5605687A (en) * 1992-05-15 1997-02-25 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for repair of electrical injury
AU6409594A (en) * 1993-03-16 1994-10-11 Alliance Pharmaceutical Corporation Preservation solution and method for warm organ preservation
JP2686405B2 (ja) * 1993-04-06 1997-12-08 全国農業協同組合連合会 牛受精卵の凍結保存方法
AU8131794A (en) * 1993-11-02 1995-05-23 Emory University Composition for tissue and organ transplantation preservation
US5658560A (en) * 1994-01-18 1997-08-19 Serikov; Vladimir B. Method of treating endotoxemia by administering tyloxapol
US5658962A (en) 1994-05-20 1997-08-19 Minnesota Mining And Manufacturing Company Omega-hydrofluoroalkyl ethers, precursor carboxylic acids and derivatives thereof, and their preparation and application
US5502094A (en) * 1994-05-20 1996-03-26 Minnesota Mining And Manufacturing Company Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
US5614170A (en) * 1994-11-30 1997-03-25 Hemagen/Pfc Paramagnetic complexes of N-alkyl-N-hydroxylamides of organic acids and emulsions containing same for magnetic resonance imaging (MRI)
GB9512529D0 (en) * 1995-06-20 1995-08-23 Bnfl Fluorchem Ltd Cell treatment
WO1997025978A1 (en) * 1996-01-15 1997-07-24 BELOYARTSEV, Arkady Felixovich Method of obtaining perfluorocarbon emulsions for medical purposes
SE511587C2 (sv) * 1997-07-08 1999-10-25 Sandvik Ab Sätt att tillverka skär med hål för fastspänning
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6679859B1 (en) 1997-10-24 2004-01-20 Alliance Pharmaceutical Corp. Amelioration of ischemic damage using synthetic oxygen carriers
US20010055809A1 (en) * 1998-01-30 2001-12-27 Harpal S. Mangat Extending tissue preservation
CA2345895A1 (en) * 1998-09-09 2000-03-16 University Of Pittsburgh Improved artificial blood fluids
KR20000023874A (ko) * 1999-04-09 2000-05-06 김욱진 고농도산소용해수액
RU2200544C1 (ru) * 2001-06-29 2003-03-20 Воробьев Сергей Иванович Способ получения стерильных перфторуглеродных эмульсий для искусственных перфторуглеродных кровезаменителей
CN103931605B (zh) 2004-10-07 2015-11-18 特兰斯迈迪茨公司 用于活体外器官护理的系统和方法
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) * 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US8535691B2 (en) * 2006-02-16 2013-09-17 Peach Technologies, LLC. Perflurochemical treatment process and apparatus
KR100767811B1 (ko) 2006-10-25 2007-10-17 강원대학교산학협력단 이식 장기의 체외 관류방법
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US20090226876A1 (en) * 2007-11-19 2009-09-10 THE UNITED STATES GOVERMENT as represented by the DEPARTMENT OF VETERAN'S AFFAIRS Compositions And Methods For Cardiovascular Surgery
US8420380B2 (en) 2008-01-31 2013-04-16 Transmedics, Inc. Systems and methods for ex vivo lung care
EP2393353A4 (en) * 2009-02-05 2013-12-25 Resolvyx Pharmaceuticals Inc COMPOSITIONS AND METHODS OF ORGAN CONSERVATION
CA2756685C (en) * 2009-04-15 2019-12-24 Tenax Therapeutics, Inc. Emulsions of perfluorocarbons
US20120064178A1 (en) * 2010-09-13 2012-03-15 Carolyn Flora Anne Dean Cell-8 Solution
US20130011823A1 (en) 2011-04-14 2013-01-10 Hassanein Waleed H Organ care solution for ex-vivo machine perfusion of donor lungs
US20130330706A1 (en) * 2012-06-06 2013-12-12 Evan C. Unger Fluid for Suspended Animation
HK1221119A1 (zh) 2013-03-28 2017-05-26 The Trustees Of Columbia University In The City Of New York 用omega-3甘油酯再灌注促进对用於移植的供体器官的保护
JP2017518301A (ja) 2014-06-02 2017-07-06 トランスメディクス， インク．Ｔｒａｎｓｍｅｄｉｃｓ， Ｉｎｃ． ｅｘ−ｖｉｖｏでの臓器管理システム
CA3155169A1 (en) 2014-12-12 2016-06-16 Tevosol, Inc. Apparatus and method for organ perfusion
CA2997267A1 (en) 2015-09-09 2017-03-16 Transmedics, Inc. Aortic cannula for ex vivo organ care system
ES2968062T3 (es) 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable
EP4580680A1 (de) 2022-08-31 2025-07-09 Universität Duisburg-Essen Lecithin-modifizierte nanoskalierte sauerstoffträger (lenox)

Family Cites Families (5)

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US3843455A (en) * 1972-09-13 1974-10-22 M Bier Apparatus and technique for preservation of isolated organs through perfusion
US3911138B1 (en) * 1973-02-26 1996-10-29 Childrens Hosp Medical Center Artificial blood and method for supporting oxygen transport in animals
JPS5331209B2 (https=) * 1973-10-05 1978-09-01
JPS5835485B2 (ja) * 1976-02-03 1983-08-03 株式会社ミドリ十字 酸素運搬輸液
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0494974A4 (en) * 1989-10-04 1992-09-02 Alliance Pharmaceutical, Inc. Fluorocarbon emulsions containing amino acid based anti-inflammatory agents and buffer systems
WO2002053525A1 (en) * 2000-12-29 2002-07-11 Otkrytoe Aktsionernoe Obschestvo Nauchno-Proizvodstvennaya Firma 'perftoran' Perfluoronated cycle-containing tertiary amines used as a basis for gas-conveying emulsions and device for the production thereof

Also Published As

Publication number Publication date
JPS5551016A (en) 1980-04-14
EP0033402B1 (en) 1983-09-07
US4186253A (en) 1980-01-29
ATE4572T1 (de) 1983-09-15
JPS6210201B2 (https=) 1987-03-05
EP0033402A1 (en) 1981-08-12
WO1981002103A1 (fr) 1981-08-06

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