AU4980200A - Methods and compositions for measuring ion channel conductance - Google Patents

Methods and compositions for measuring ion channel conductance

Info

Publication number
AU4980200A
AU4980200A AU49802/00A AU4980200A AU4980200A AU 4980200 A AU4980200 A AU 4980200A AU 49802/00 A AU49802/00 A AU 49802/00A AU 4980200 A AU4980200 A AU 4980200A AU 4980200 A AU4980200 A AU 4980200A
Authority
AU
Australia
Prior art keywords
compositions
methods
ion channel
channel conductance
measuring ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49802/00A
Other languages
English (en)
Inventor
Mitchell B. Berkenpas
Vincent E. Groppi Jr.
Mark L Wolfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU4980200A publication Critical patent/AU4980200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Thin Film Transistor (AREA)
AU49802/00A 1999-05-27 2000-05-25 Methods and compositions for measuring ion channel conductance Abandoned AU4980200A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13617499P 1999-05-27 1999-05-27
US60136174 1999-05-27
PCT/US2000/011862 WO2000073431A2 (en) 1999-05-27 2000-05-25 Methods and compositions for measuring ion channel conductance

Publications (1)

Publication Number Publication Date
AU4980200A true AU4980200A (en) 2000-12-18

Family

ID=22471672

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49802/00A Abandoned AU4980200A (en) 1999-05-27 2000-05-25 Methods and compositions for measuring ion channel conductance

Country Status (5)

Country Link
US (1) US20070238168A1 (cg-RX-API-DMAC7.html)
EP (1) EP1180142A2 (cg-RX-API-DMAC7.html)
JP (1) JP2003501022A (cg-RX-API-DMAC7.html)
AU (1) AU4980200A (cg-RX-API-DMAC7.html)
WO (1) WO2000073431A2 (cg-RX-API-DMAC7.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214686B2 (en) 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
AU784644B2 (en) * 1999-12-14 2006-05-18 Pharmacia & Upjohn Company Human ion channels
GB0003069D0 (en) * 2000-02-11 2000-03-29 Cambridge Drug Discovery Ltd Improved assay
DE10006309A1 (de) 2000-02-12 2001-08-23 Aventis Pharma Gmbh Verfahren zur Identifizierung von Substanzen, die die Aktivität von hyperpolarisationsaktivierten Kationen-kanälen modulieren
WO2002016358A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
WO2002016357A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
US6492385B2 (en) 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
WO2002017358A2 (en) 2000-08-21 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists)
US6599916B2 (en) 2000-08-21 2003-07-29 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
WO2002061074A1 (fr) * 2001-01-30 2002-08-08 Takeda Chemical Industries, Ltd. Nouvelle proteine et adn la comprenant
PE20021019A1 (es) 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
WO2003018585A1 (en) 2001-08-24 2003-03-06 Pharmacia & Upjohn Company Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
KR100614900B1 (ko) 2001-10-02 2006-08-25 파마시아 앤드 업존 캄파니 엘엘씨 질병의 치료를 위한 아자비시클릭-치환된 융합-헤테로아릴화합물
US6849620B2 (en) 2001-10-26 2005-02-01 Pfizer Inc N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
CA2466375A1 (en) 2001-11-08 2003-05-15 Pharmacia & Upjohn Company Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
EP1442037A1 (en) 2001-11-09 2004-08-04 PHARMACIA & UPJOHN COMPANY Azabicyclic-phenyl-fused-heterocyclic compounds and their use as alpha7 nachr ligands
AU2003210730A1 (en) 2002-02-15 2003-09-09 Pharmacia And Upjohn Company Azabicyclo-substituted benzoylamides and thioamides for treatment of cns-related disorders
CA2476624A1 (en) 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
US6858613B2 (en) 2002-02-19 2005-02-22 Pfizer Inc. Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease
BR0307874A (pt) * 2002-02-20 2004-12-28 Upjohn Co Atividade de compostos azabicìclicos com receptor de acetilcolina nicotìnica alfa7
CA2487236A1 (en) 2002-05-09 2003-11-20 Memory Pharmaceuticals Corporation Qm-7 and qt-6 cells transfected with mutant cell surface expressed channel receptors and assays using the transfected cells
EP1542999A1 (en) 2002-08-01 2005-06-22 Pharmacia & Upjohn Company LLC 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity
EP1581558A2 (en) * 2003-01-07 2005-10-05 Neuromed Technologies, Inc. Fluorescence based t-type channel assay
ATE517176T1 (de) * 2004-10-15 2011-08-15 Monell Chemical Senses Centre Verfahren zur kultivierung von geschmackszellen aus säugern
ATE482959T1 (de) 2005-08-22 2010-10-15 Targacept Inc Heteroarylsubstituierte diazatricycloalkane, verfahren zu deren herstellung und deren anwendung
JP5241255B2 (ja) * 2008-02-01 2013-07-17 生化学工業株式会社 関節痛の評価方法
US20110098312A1 (en) 2008-05-12 2011-04-28 Targacept ,Inc Methods for preventing the development of retinopathy by the oral administration of nnr ligands
JP5775819B2 (ja) * 2008-10-09 2015-09-09 ハワード ヒューズ メディカル インスティチュート 新規なキメラリガンド開口型イオンチャネルおよびその使用方法
BR112012027282B1 (pt) 2010-04-26 2020-09-29 Novartis Ag Meio de cultura de células aperfeiçoado e processo para a produção de um polipeptídeo recombinante
JP2021503960A (ja) 2017-11-27 2021-02-15 コーダ バイオセラピューティクス， インコーポレイテッド 神経疾患のための組成物および方法
CN111378025A (zh) * 2020-03-26 2020-07-07 集美大学 河豚毒素结合蛋白tfPSTBP2、核苷酸序列、其多克隆抗体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670113A (en) * 1991-12-20 1997-09-23 Sibia Neurosciences, Inc. Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same
GB2286397C (en) * 1993-03-08 1997-09-10 Sibia Neurosciences Inc Human neuronal nicotinic acetylcholine receptor compositions and methods of applying same
US6323000B2 (en) * 1996-12-20 2001-11-27 Clark A. Briggs Variant human α7 acetylcholine receptor subunit, and methods of production and uses thereof
AU9673198A (en) * 1997-10-02 1999-04-27 Aclara Biosciences, Inc. Capillary assays involving separation of free and bound species

Also Published As

Publication number Publication date
WO2000073431A2 (en) 2000-12-07
EP1180142A2 (en) 2002-02-20
JP2003501022A (ja) 2003-01-14
WO2000073431A3 (en) 2001-05-03
US20070238168A1 (en) 2007-10-11
WO2000073431B1 (en) 2001-07-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase