AU497500B2 - Adriamycins - Google Patents

Adriamycins

Info

Publication number
AU497500B2
AU497500B2 AU79263/75A AU7926375A AU497500B2 AU 497500 B2 AU497500 B2 AU 497500B2 AU 79263/75 A AU79263/75 A AU 79263/75A AU 7926375 A AU7926375 A AU 7926375A AU 497500 B2 AU497500 B2 AU 497500B2
Authority
AU
Australia
Prior art keywords
adriamycins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU79263/75A
Other languages
English (en)
Other versions
AU7926375A (en
Inventor
F. Dimarco A. & Perico S Arcamone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of AU7926375A publication Critical patent/AU7926375A/en
Application granted granted Critical
Publication of AU497500B2 publication Critical patent/AU497500B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU79263/75A 1974-03-22 1975-03-19 Adriamycins Expired AU497500B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1278374A GB1457632A (en) 1974-03-22 1974-03-22 Adriamycins
GBGB12733/74 1974-03-22

Publications (2)

Publication Number Publication Date
AU7926375A AU7926375A (en) 1976-09-23
AU497500B2 true AU497500B2 (en) 1978-12-14

Family

ID=10011048

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79263/75A Expired AU497500B2 (en) 1974-03-22 1975-03-19 Adriamycins

Country Status (18)

Country Link
US (1) US4058519A (OSRAM)
JP (1) JPS5840555B2 (OSRAM)
AT (1) AT338420B (OSRAM)
AU (1) AU497500B2 (OSRAM)
BE (1) BE826978A (OSRAM)
CA (1) CA1046507A (OSRAM)
CH (1) CH612947A5 (OSRAM)
DE (1) DE2510866C3 (OSRAM)
DK (1) DK153158C (OSRAM)
ES (1) ES435833A1 (OSRAM)
FR (1) FR2264555B1 (OSRAM)
GB (1) GB1457632A (OSRAM)
HK (1) HK882A (OSRAM)
MY (1) MY103912A (OSRAM)
NL (1) NL176635C (OSRAM)
SE (1) SE434844B (OSRAM)
SU (1) SU583763A3 (OSRAM)
ZA (1) ZA751781B (OSRAM)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133877A (en) * 1976-07-08 1979-01-09 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and use therefor
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4345068A (en) * 1979-11-22 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
EP0051280B1 (en) * 1980-11-01 1984-07-11 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
DE3172152D1 (en) * 1980-11-01 1985-10-10 Erba Farmitalia Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
DE3500029A1 (de) * 1985-01-02 1986-09-04 Farmitalia Carlo Erba S.p.A., Mailand/Milano Anthracyclinester
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
JPS61172891A (ja) * 1985-01-24 1986-08-04 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ アントラサイクリン類エステルの製法
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
PT848009E (pt) 1996-12-16 2000-11-30 Pharmachemie Bv Processo para a preparacao de epirubicina ou seus sais de adicao de acido a partir de daunorubicina
US6653455B1 (en) 1998-10-16 2003-11-25 Mercian Corporation Crystallization of doxorubicin hydrochloride
KR100850408B1 (ko) * 2000-08-10 2008-08-04 동아제약주식회사 안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
KR100785966B1 (ko) * 2000-08-10 2007-12-14 동아제약주식회사 안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
ATE520702T1 (de) * 2003-07-02 2011-09-15 Solux Corp Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür
AU2006207321B2 (en) 2005-01-21 2012-09-06 Astex Therapeutics Limited Pharmaceutical compounds
PL375008A1 (pl) 2005-05-12 2006-11-13 Institut National De La Sante Et De La Recherche Medicale, Inserm Nowe zastosowanie medyczne chlorowodorku epirubicyny
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
AR074977A1 (es) 2008-12-23 2011-03-02 Pharmasset Inc Sintesis de nucleosidos de purina
CN102753563A (zh) 2008-12-23 2012-10-24 吉利德制药有限责任公司 核苷类似物
KR20110099138A (ko) 2008-12-23 2011-09-06 파마셋 인코포레이티드 뉴클레오시드 포스포르아미데이트
AU2011235112B2 (en) 2010-03-31 2015-07-09 Gilead Sciences, Inc. Nucleoside phosphoramidates
WO2017120729A1 (zh) * 2016-01-11 2017-07-20 浙江海正药业股份有限公司 一种盐酸表柔比星的制备方法及其中间体
EA201892075A1 (ru) 2016-03-15 2019-04-30 Оризон Дженомикс, С.А. Комбинации ингибиторов lsd1 для применения для лечения солидных опухолей

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356674A (en) * 1961-07-07 1967-12-05 Rikagaku Kenkyusho 3-c-hydroxymethyl-3, 5-didesoxy-l-lyxofuranose and its derivatives, and a process for the production thereof
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) * 1968-05-23 1971-12-21 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid
US3651090A (en) * 1969-12-17 1972-03-21 Cutter Lab 1 3-dioxolan-4-yl-alkyl guanidines
FR2183710A1 (en) * 1972-05-06 1973-12-21 Farmaceutici Italia Daunomycin (hydrochloride) prepn - by reaction of daunomycinone with daunosamines, useful as antitumour agent and anti-leucemic

Also Published As

Publication number Publication date
ZA751781B (en) 1976-02-25
MY103912A (en) 1993-10-30
GB1457632A (en) 1976-12-08
US4058519A (en) 1977-11-15
DE2510866A1 (de) 1975-10-02
ATA207475A (de) 1976-12-15
SE434844B (sv) 1984-08-20
AU7926375A (en) 1976-09-23
NL176635B (nl) 1984-12-17
BE826978A (fr) 1975-09-22
DK153158C (da) 1989-01-16
AT338420B (de) 1977-08-25
SU583763A3 (ru) 1977-12-05
HK882A (en) 1982-01-22
FR2264555A1 (OSRAM) 1975-10-17
DK153158B (da) 1988-06-20
DE2510866C3 (de) 1980-08-14
NL7502934A (nl) 1975-09-24
SE7503215L (OSRAM) 1975-09-23
FR2264555B1 (OSRAM) 1980-01-11
ES435833A1 (es) 1976-12-01
CA1046507A (en) 1979-01-16
CH612947A5 (OSRAM) 1979-08-31
JPS5840555B2 (ja) 1983-09-06
DE2510866B2 (de) 1979-12-06
JPS50126656A (OSRAM) 1975-10-04
DK114475A (OSRAM) 1975-09-23
NL176635C (nl) 1985-05-17

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