AU3443493A - 3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity - Google Patents

3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity

Info

Publication number
AU3443493A
AU3443493A AU34434/93A AU3443493A AU3443493A AU 3443493 A AU3443493 A AU 3443493A AU 34434/93 A AU34434/93 A AU 34434/93A AU 3443493 A AU3443493 A AU 3443493A AU 3443493 A AU3443493 A AU 3443493A
Authority
AU
Australia
Prior art keywords
quinoxalines
quinazolines
substituted imidazo
cns activity
cns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34434/93A
Other languages
English (en)
Inventor
Jackson B. Hester Jr.
Eric Jon Jacobsen
Louis L. Skaletzky
Ruth Elizabeth Tenbrink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU3443493A publication Critical patent/AU3443493A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU34434/93A 1992-02-19 1993-01-25 3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity Abandoned AU3443493A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83851992A 1992-02-19 1992-02-19
US838519 1992-02-19

Publications (1)

Publication Number Publication Date
AU3443493A true AU3443493A (en) 1993-09-13

Family

ID=25277305

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34434/93A Abandoned AU3443493A (en) 1992-02-19 1993-01-25 3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity

Country Status (4)

Country Link
EP (1) EP0626966A1 (de)
JP (1) JPH07503970A (de)
AU (1) AU3443493A (de)
WO (1) WO1993017025A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211365B1 (en) 1996-01-19 2001-04-03 Neurogen Corporation Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
US5804686A (en) * 1996-01-19 1998-09-08 Neurogen Corporation fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
US5792766A (en) 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
US5677309A (en) * 1996-03-22 1997-10-14 Neurogen Corporation 1,2,4-triazolo 4,3-c! quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones; a new class of GABA brain receptor ligands
EP0888300A1 (de) 1996-03-22 1999-01-07 Neurogen Corporation Kondensierte pyrrolcarboxamide als gaba-gehirn-rezeptor-liganden
US5955465A (en) * 1996-03-22 1999-09-21 Neurogen Corporation 1,2,4-triazolo 4,3-c!quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones
OA12015A (en) 1999-08-31 2006-04-19 Neurogen Corp Fused pyrrolecarboxamides: gaba brain receptor ligands.
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
EP2404922B1 (de) 2009-03-05 2016-11-09 Astellas Pharma Inc. Chinoxalinverbindungen
EA201390354A1 (ru) 2010-09-07 2013-08-30 Астеллас Фарма Инк. Хиноксалиновое соединение
GB2574862A (en) * 2018-06-21 2019-12-25 Curadev Pharma Ltd Azaheterocyclic small molecule modulators of human STING

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK443589D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
EP0626966A1 (de) 1994-12-07
JPH07503970A (ja) 1995-04-27
WO1993017025A1 (en) 1993-09-02

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