GB2205565B - Imidazo-[1,2-a]-pyrimidin-2-oyl and imidazo-[1,2-a]quinazolin-2-oyl cyclopropane derivatives - Google Patents

Imidazo-[1,2-a]-pyrimidin-2-oyl and imidazo-[1,2-a]quinazolin-2-oyl cyclopropane derivatives

Info

Publication number
GB2205565B
GB2205565B GB8812466A GB8812466A GB2205565B GB 2205565 B GB2205565 B GB 2205565B GB 8812466 A GB8812466 A GB 8812466A GB 8812466 A GB8812466 A GB 8812466A GB 2205565 B GB2205565 B GB 2205565B
Authority
GB
United Kingdom
Prior art keywords
oyl
imidazo
quinazolin
pyrimidin
cyclopropane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8812466A
Other versions
GB2205565A (en
GB8812466D0 (en
Inventor
Colin Robert Gardner
Charles John Robert Hedgecock
Stuart Donald Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roussel Laboratories Ltd
Original Assignee
Roussel Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Laboratories Ltd filed Critical Roussel Laboratories Ltd
Publication of GB8812466D0 publication Critical patent/GB8812466D0/en
Publication of GB2205565A publication Critical patent/GB2205565A/en
Application granted granted Critical
Publication of GB2205565B publication Critical patent/GB2205565B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8812466A 1987-05-27 1988-05-26 Imidazo-[1,2-a]-pyrimidin-2-oyl and imidazo-[1,2-a]quinazolin-2-oyl cyclopropane derivatives Expired - Lifetime GB2205565B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712466A GB8712466D0 (en) 1987-05-27 1987-05-27 Chemical compounds

Publications (3)

Publication Number Publication Date
GB8812466D0 GB8812466D0 (en) 1988-06-29
GB2205565A GB2205565A (en) 1988-12-14
GB2205565B true GB2205565B (en) 1991-05-15

Family

ID=10617989

Family Applications (2)

Application Number Title Priority Date Filing Date
GB878712466A Pending GB8712466D0 (en) 1987-05-27 1987-05-27 Chemical compounds
GB8812466A Expired - Lifetime GB2205565B (en) 1987-05-27 1988-05-26 Imidazo-[1,2-a]-pyrimidin-2-oyl and imidazo-[1,2-a]quinazolin-2-oyl cyclopropane derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB878712466A Pending GB8712466D0 (en) 1987-05-27 1987-05-27 Chemical compounds

Country Status (8)

Country Link
EP (1) EP0293294A3 (en)
JP (1) JPS63307878A (en)
AU (1) AU1673388A (en)
DK (1) DK282988A (en)
GB (2) GB8712466D0 (en)
HU (1) HU199474B (en)
PT (1) PT87584B (en)
ZA (1) ZA883176B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201406311UA (en) 2012-04-05 2014-11-27 Chdi Foundation Inc Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
US9938252B2 (en) 2013-09-26 2018-04-10 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
US9884853B2 (en) 2013-09-26 2018-02-06 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128989A (en) * 1982-08-27 1984-05-10 Roussel Lab Ltd Imidazo]1,2-apyrimidine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8620060D0 (en) * 1986-08-18 1986-10-01 Roussel Lab Ltd Chemical compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128989A (en) * 1982-08-27 1984-05-10 Roussel Lab Ltd Imidazo]1,2-apyrimidine

Also Published As

Publication number Publication date
GB8712466D0 (en) 1987-07-01
GB2205565A (en) 1988-12-14
HUT47579A (en) 1989-03-28
JPS63307878A (en) 1988-12-15
EP0293294A2 (en) 1988-11-30
ZA883176B (en) 1989-07-26
DK282988D0 (en) 1988-05-24
GB8812466D0 (en) 1988-06-29
PT87584B (en) 1992-09-30
PT87584A (en) 1989-05-31
AU1673388A (en) 1988-12-01
DK282988A (en) 1988-11-28
EP0293294A3 (en) 1990-04-25
HU199474B (en) 1990-02-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960526