AU2383884A - Lactam peptides - Google Patents

Lactam peptides

Info

Publication number
AU2383884A
AU2383884A AU23838/84A AU2383884A AU2383884A AU 2383884 A AU2383884 A AU 2383884A AU 23838/84 A AU23838/84 A AU 23838/84A AU 2383884 A AU2383884 A AU 2383884A AU 2383884 A AU2383884 A AU 2383884A
Authority
AU
Australia
Prior art keywords
acid
formula
compound
group
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU23838/84A
Other languages
English (en)
Inventor
William Bencze
Bruno Kamber
Angelo Storni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU2383884A publication Critical patent/AU2383884A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU23838/84A 1983-01-27 1984-01-26 Lactam peptides Abandoned AU2383884A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH45383 1983-01-27
CH453/83 1983-01-27

Publications (1)

Publication Number Publication Date
AU2383884A true AU2383884A (en) 1984-08-02

Family

ID=4187370

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23838/84A Abandoned AU2383884A (en) 1983-01-27 1984-01-26 Lactam peptides

Country Status (12)

Country Link
EP (1) EP0115472A3 (enExample)
JP (1) JPS59141559A (enExample)
KR (1) KR840007571A (enExample)
AU (1) AU2383884A (enExample)
DD (1) DD216005A5 (enExample)
DK (1) DK35884A (enExample)
FI (1) FI840260L (enExample)
GR (1) GR81746B (enExample)
IL (1) IL70772A0 (enExample)
NO (1) NO840310L (enExample)
PT (1) PT78007B (enExample)
ZA (1) ZA84560B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE943625C (de) * 1943-06-28 1956-05-24 Ferguson Harry Inc Seitensteuerungseinrichtung fuer ein landwirtschaftliches Schlepperanbaugeraet
JPH0696574B2 (ja) * 1987-09-16 1994-11-30 三菱化成株式会社 ４−ピペリジンカルボキサミド誘導体
JPH0696575B2 (ja) * 1987-09-17 1994-11-30 三菱化成株式会社 ４−アミノピリジン誘導体及びその酸付加塩
JP2997488B2 (ja) * 1989-12-25 2000-01-11 興研株式会社 腫瘍細胞増殖抑制剤
CA2172125A1 (en) * 1993-09-30 1995-04-06 S. Jane Desolms Inhibitors of farnesyl-protein transferase
CA2360740A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
US20050065205A1 (en) 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
TW201207390A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Method for screening agent for antidepressant activity
US20070054890A1 (en) 2005-07-29 2007-03-08 Alkon Daniel L Protein synthesis required for long-term memory is induced by PKC activation on days preceding associative learning
CN101848726A (zh) 2007-02-09 2010-09-29 布朗歇特洛克菲勒神经科学研究所 苔藓抑素、苔藓抑素类似物和其它相关物质对头部创伤引起的记忆缺陷和脑损伤的疗效

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams

Also Published As

Publication number Publication date
PT78007B (en) 1986-06-18
DD216005A5 (de) 1984-11-28
FI840260A7 (fi) 1984-07-28
EP0115472A2 (de) 1984-08-08
PT78007A (en) 1984-02-01
FI840260L (fi) 1984-07-28
DK35884D0 (da) 1984-01-26
KR840007571A (ko) 1984-12-08
GR81746B (enExample) 1984-12-12
ZA84560B (en) 1984-09-26
JPS59141559A (ja) 1984-08-14
EP0115472A3 (de) 1985-10-02
IL70772A0 (en) 1984-04-30
NO840310L (no) 1984-07-30
DK35884A (da) 1984-07-28
FI840260A0 (fi) 1984-01-23

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