AU2028497A - Metabotropic gaba{b} receptors, receptor-specific ligands and their uses - Google Patents

Metabotropic gaba{b} receptors, receptor-specific ligands and their uses

Info

Publication number
AU2028497A
AU2028497A AU20284/97A AU2028497A AU2028497A AU 2028497 A AU2028497 A AU 2028497A AU 20284/97 A AU20284/97 A AU 20284/97A AU 2028497 A AU2028497 A AU 2028497A AU 2028497 A AU2028497 A AU 2028497A
Authority
AU
Australia
Prior art keywords
receptor
gabab
proteins
receptors
gabab receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU20284/97A
Other languages
English (en)
Inventor
Bernhard Bettler
Helmut Bittiger
Wolfgang Frostl
Klemens Kaupmann
Stuart John Mickel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Publication of AU2028497A publication Critical patent/AU2028497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU20284/97A 1996-05-30 1997-03-19 Metabotropic gaba{b} receptors, receptor-specific ligands and their uses Abandoned AU2028497A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US65571696A 1996-05-30 1996-05-30
US08655716 1996-05-30
US75609196A 1996-11-22 1996-11-22
US08756091 1996-11-22
PCT/EP1997/001370 WO1997046675A1 (en) 1996-05-30 1997-03-19 Metabotropic gaba[b] receptors, receptor-specific ligands and their uses

Publications (1)

Publication Number Publication Date
AU2028497A true AU2028497A (en) 1998-01-05

Family

ID=27097014

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20284/97A Abandoned AU2028497A (en) 1996-05-30 1997-03-19 Metabotropic gaba{b} receptors, receptor-specific ligands and their uses

Country Status (9)

Country Link
EP (1) EP0907731B1 (enExample)
JP (3) JP4131568B2 (enExample)
AT (1) ATE290079T1 (enExample)
AU (1) AU2028497A (enExample)
CA (1) CA2254862A1 (enExample)
DE (1) DE69732631T2 (enExample)
ES (1) ES2239352T3 (enExample)
PT (1) PT907731E (enExample)
WO (1) WO1997046675A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2308102A1 (en) * 1997-10-27 1999-05-06 Astrazeneca Aktiebolag New nucleotide sequences
JP2002502859A (ja) * 1998-02-05 2002-01-29 メルク エンド カムパニー インコーポレーテッド 新規ｇａｂａｂ受容体ｄｎａ配列
EP0937777A3 (en) * 1998-02-20 1999-11-24 Smithkline Beecham Plc GABA receptors and their uses
EP1066325A1 (en) * 1998-04-03 2001-01-10 Nps Pharmaceuticals, Inc. G-protein fusion receptors and chimeric gaba b? receptors
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
WO1999051636A2 (en) * 1998-04-03 1999-10-14 Nps Pharmaceuticals, Inc. Gaba b receptor
WO1999058567A1 (en) * 1998-05-08 1999-11-18 Smithkline Beecham Corporation GABAB1b RECEPTOR
AUPP438498A0 (en) * 1998-06-29 1998-07-23 Garvan Institute Of Medical Research Novel Gaba-B receptor
JP2002523070A (ja) * 1998-09-01 2002-07-30 スミスクライン ビーチャム コーポレーション Ｇａｂａｂ１ａａ受容体
WO2000014222A2 (en) * 1998-09-07 2000-03-16 Glaxo Group Limited GABAB RECEPTOR SUBTYPES GABAB-R1c AND GABAB-R2 AND HETERODIMERS THEREOF
GB9819420D0 (en) 1998-09-07 1998-10-28 Glaxo Group Ltd Novel receptor
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
SE9901659D0 (sv) 1999-05-06 1999-05-06 Astra Ab New methods
US20010053849A1 (en) * 1999-06-16 2001-12-20 Mary Jeanne Kreek Plural biological sample arrays, and preparation and uses thereof
US6787646B1 (en) * 1999-11-12 2004-09-07 Immusol, Inc. Tumor suppressor molecules and methods of use
DE19955408A1 (de) * 1999-11-18 2001-05-23 Bayer Ag GABA-B-Rezeptoren
WO2004083855A1 (en) * 2003-03-19 2004-09-30 Solvo Biotechnology, Inc. Method for the identification of cells specifically modulating slow inhibition in the neocortex
CN102532197A (zh) * 2010-12-24 2012-07-04 中国科学院上海药物研究所 一类光亲和标记双功能探针分子及其制备方法和应用
CN108588087B (zh) * 2018-05-16 2022-06-03 南京农业大学 一种提高植物抗病性的基因GmLecRK-R及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids

Also Published As

Publication number Publication date
CA2254862A1 (en) 1997-12-11
DE69732631D1 (de) 2005-04-07
EP0907731B1 (en) 2005-03-02
ATE290079T1 (de) 2005-03-15
JP2000515005A (ja) 2000-11-14
JP4202403B2 (ja) 2008-12-24
JP2008113662A (ja) 2008-05-22
JP2007289188A (ja) 2007-11-08
PT907731E (pt) 2005-07-29
DE69732631T2 (de) 2005-12-29
WO1997046675A1 (en) 1997-12-11
ES2239352T3 (es) 2005-09-16
EP0907731A1 (en) 1999-04-14
JP4131568B2 (ja) 2008-08-13

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