AU2022275653A1 - Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection - Google Patents

Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection Download PDF

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Publication number
AU2022275653A1
AU2022275653A1 AU2022275653A AU2022275653A AU2022275653A1 AU 2022275653 A1 AU2022275653 A1 AU 2022275653A1 AU 2022275653 A AU2022275653 A AU 2022275653A AU 2022275653 A AU2022275653 A AU 2022275653A AU 2022275653 A1 AU2022275653 A1 AU 2022275653A1
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Australia
Prior art keywords
amino acid
sarbecovirus
seq
construct
acid construct
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Abandoned
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AU2022275653A
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English (en)
Inventor
Wan Ni CHIA
Chee Wah TAN
Linfa Wang
Feng Zhu
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National University of Singapore
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National University of Singapore
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Publication date
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Publication of AU2022275653A1 publication Critical patent/AU2022275653A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
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    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
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    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18441—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18443—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20241—Use of virus, viral particle or viral elements as a vector
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2022275653A 2021-05-15 2022-05-15 Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection Abandoned AU2022275653A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10202105099S 2021-05-15
SG10202105099S 2021-05-15
PCT/SG2022/050322 WO2022245287A1 (en) 2021-05-15 2022-05-15 Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection

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AU2022275653A1 true AU2022275653A1 (en) 2024-01-04

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AU2022275653A Abandoned AU2022275653A1 (en) 2021-05-15 2022-05-15 Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection

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Country Link
US (1) US20240261389A1 (https=)
EP (1) EP4341275A4 (https=)
JP (1) JP2024518548A (https=)
KR (1) KR20240009981A (https=)
CN (1) CN117396493A (https=)
AU (1) AU2022275653A1 (https=)
CA (1) CA3218851A1 (https=)
WO (1) WO2022245287A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025021681A1 (en) 2023-07-21 2025-01-30 National University Of Singapore Immunogenic polypeptides

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Publication number Publication date
JP2024518548A (ja) 2024-05-01
EP4341275A4 (en) 2025-04-16
CA3218851A1 (en) 2022-11-24
KR20240009981A (ko) 2024-01-23
WO2022245287A9 (en) 2023-08-31
US20240261389A1 (en) 2024-08-08
EP4341275A1 (en) 2024-03-27
WO2022245287A1 (en) 2022-11-24
CN117396493A (zh) 2024-01-12

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