AU2022247468A1 - Spatial mapping by serial primer extension - Google Patents

Spatial mapping by serial primer extension Download PDF

Info

Publication number
AU2022247468A1
AU2022247468A1 AU2022247468A AU2022247468A AU2022247468A1 AU 2022247468 A1 AU2022247468 A1 AU 2022247468A1 AU 2022247468 A AU2022247468 A AU 2022247468A AU 2022247468 A AU2022247468 A AU 2022247468A AU 2022247468 A1 AU2022247468 A1 AU 2022247468A1
Authority
AU
Australia
Prior art keywords
sequence
barcoded
nucleic acid
particles
acid molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022247468A
Other languages
English (en)
Other versions
AU2022247468A9 (en
Inventor
Simon Fredriksson
Filip KARLSSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pixelgen Technologies AB
Original Assignee
Pixelgen Technologies AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=81327110&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2022247468(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pixelgen Technologies AB filed Critical Pixelgen Technologies AB
Publication of AU2022247468A1 publication Critical patent/AU2022247468A1/en
Publication of AU2022247468A9 publication Critical patent/AU2022247468A9/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analogue/Digital Conversion (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
AU2022247468A 2021-03-30 2022-03-29 Spatial mapping by serial primer extension Pending AU2022247468A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163168132P 2021-03-30 2021-03-30
US63/168,132 2021-03-30
PCT/IB2022/052862 WO2022208327A1 (en) 2021-03-30 2022-03-29 Spatial mapping by serial primer extension

Publications (2)

Publication Number Publication Date
AU2022247468A1 true AU2022247468A1 (en) 2023-10-05
AU2022247468A9 AU2022247468A9 (en) 2024-02-22

Family

ID=81327110

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022247468A Pending AU2022247468A1 (en) 2021-03-30 2022-03-29 Spatial mapping by serial primer extension

Country Status (7)

Country Link
US (2) US12123050B2 (https=)
EP (2) EP4303315B1 (https=)
JP (1) JP2024512943A (https=)
CN (1) CN117396612B (https=)
AU (1) AU2022247468A1 (https=)
CA (1) CA3213800A1 (https=)
WO (1) WO2022208327A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4555322B1 (en) 2022-09-27 2025-10-22 Pixelgen Technologies Ab Method for fixing primary antibodies to a biological sample
WO2024154075A1 (en) 2023-01-18 2024-07-25 Pixelgen Technologies Ab Gap-fill ligation and primer extension reactions employing exonuclease-resistant or capture moiety means
WO2024241162A1 (en) 2023-05-25 2024-11-28 Pixelgen Technologies Ab Peptide for site-specific antibody conjugation and method of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948902A (en) 1997-11-20 1999-09-07 South Alabama Medical Science Foundation Antisense oligonucleotides to human serine/threonine protein phosphatase genes
CN101410530B (zh) * 2003-04-18 2013-03-27 贝克顿·迪金森公司 免疫-扩增
US20050233340A1 (en) 2004-04-20 2005-10-20 Barrett Michael T Methods and compositions for assessing CpG methylation
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
WO2012057689A1 (en) 2010-10-29 2012-05-03 Ge Healthcare Bio-Sciences Ab Proximity ligation technology for western blot applications
WO2012106385A2 (en) 2011-01-31 2012-08-09 Apprise Bio, Inc. Methods of identifying multiple epitopes in cells
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
GB201201547D0 (en) * 2012-01-30 2012-03-14 Olink Ab Method and product
CN105745334B (zh) * 2013-09-30 2019-12-10 吴迪 通过使用邻近条形编码分析分子复合物的概况的方法
EP3058091B1 (en) 2013-10-18 2020-03-25 The Broad Institute, Inc. Spatial and cellular mapping of biomolecules in situ by high-throughput sequencing
US20150298091A1 (en) * 2014-04-21 2015-10-22 President And Fellows Of Harvard College Systems and methods for barcoding nucleic acids
US11639522B2 (en) 2015-01-30 2023-05-02 President And Fellows Of Harvard College Microscope-free imaging
GB2539675B (en) * 2015-06-23 2017-11-22 Cs Genetics Ltd Libraries of multimeric barcoding reagents and kits thereof for labelling nucleic acids for sequencing
CA3176469A1 (en) * 2015-07-27 2017-02-02 Illumina, Inc. Spatial mapping of nucleic acid sequence information
WO2017044893A1 (en) 2015-09-11 2017-03-16 The Broad Institute, Inc. Dna microscopy
US11352667B2 (en) * 2016-06-21 2022-06-07 10X Genomics, Inc. Nucleic acid sequencing
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US11549135B2 (en) * 2018-09-14 2023-01-10 The Broad Institute, Inc. Oligonucleotide-coupled antibodies for single cell or single complex protein measurements
CN112867801B (zh) * 2018-11-30 2024-07-12 Illumina公司 使用单一测定分析多种分析物
AU2020357801A1 (en) * 2019-09-30 2022-04-14 Yale University Deterministic Barcoding for spatial omics sequencing
CN114616344B (zh) * 2019-10-28 2026-03-31 普赛尔根技术股份公司 用于绘制滚环扩增产物图谱的方法

Also Published As

Publication number Publication date
EP4303315B1 (en) 2024-11-06
US12123050B2 (en) 2024-10-22
US12416040B2 (en) 2025-09-16
AU2022247468A9 (en) 2024-02-22
EP4298240A1 (en) 2024-01-03
US20240175078A1 (en) 2024-05-30
CN117396612A (zh) 2024-01-12
EP4298240B1 (en) 2024-06-26
WO2022208327A1 (en) 2022-10-06
US20250011846A1 (en) 2025-01-09
CN117396612B (zh) 2025-02-28
EP4303315A3 (en) 2024-02-21
EP4303315A2 (en) 2024-01-10
CA3213800A1 (en) 2022-10-06
JP2024512943A (ja) 2024-03-21
EP4298240C0 (en) 2024-06-26

Similar Documents

Publication Publication Date Title
US12416040B2 (en) Spatial mapping by serial primer extension
JP5806213B2 (ja) 核酸の特異的解析のためのプローブ
WO2020115511A2 (en) Reagents and methods for the analysis of microparticles
JP7684984B2 (ja) ローリングサークル増幅産物をマッピングするための方法
JP2006507003A (ja) 二重鎖プロモーターの一本鎖をコードするプライマーの使用法
MX2013003349A (es) Captura directa, amplificacion y secuenciacion de objetivo adn usando cebadores inmovilizados.
US20240336959A1 (en) Method for making a physical map of a population of barcoded particles
US20250171828A1 (en) Rolling circle amplification product having multiple free ends
US20240117411A1 (en) Methods for preparing capture substrates
US20250059530A1 (en) Labeling and analysis method for single-cell nucleic acid
CN116635536A (zh) 用于制作条形码化颗粒群的物理图谱的方法

Legal Events

Date Code Title Description
SREP Specification republished