AU2021351498A1 - Methods of detecting isoaspartic acid - Google Patents
Methods of detecting isoaspartic acid Download PDFInfo
- Publication number
- AU2021351498A1 AU2021351498A1 AU2021351498A AU2021351498A AU2021351498A1 AU 2021351498 A1 AU2021351498 A1 AU 2021351498A1 AU 2021351498 A AU2021351498 A AU 2021351498A AU 2021351498 A AU2021351498 A AU 2021351498A AU 2021351498 A1 AU2021351498 A1 AU 2021351498A1
- Authority
- AU
- Australia
- Prior art keywords
- protein
- soasp
- peptide
- mass spectrometry
- fragmentation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063086557P | 2020-10-01 | 2020-10-01 | |
| US63/086,557 | 2020-10-01 | ||
| US202163218186P | 2021-07-02 | 2021-07-02 | |
| US63/218,186 | 2021-07-02 | ||
| PCT/US2021/052783 WO2022072583A1 (en) | 2020-10-01 | 2021-09-30 | Methods of detecting isoaspartic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2021351498A1 true AU2021351498A1 (en) | 2023-05-04 |
| AU2021351498A9 AU2021351498A9 (en) | 2025-03-27 |
Family
ID=78621972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021351498A Pending AU2021351498A1 (en) | 2020-10-01 | 2021-09-30 | Methods of detecting isoaspartic acid |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230366889A1 (https=) |
| EP (1) | EP4222500B1 (https=) |
| JP (1) | JP2023546796A (https=) |
| CN (1) | CN116348770A (https=) |
| AU (1) | AU2021351498A1 (https=) |
| CA (1) | CA3196920A1 (https=) |
| ES (1) | ES3059573T3 (https=) |
| MX (1) | MX2023003862A (https=) |
| TW (1) | TWI907533B (https=) |
| WO (1) | WO2022072583A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114144668B (zh) * | 2019-07-17 | 2025-02-11 | 株式会社岛津制作所 | 异天冬氨酸的分析方法和质谱分析装置 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190073452A1 (en) * | 2015-09-25 | 2019-03-07 | Bioanalytix, Inc. | Method for determining the in vivo comparability of a biologic drug and a reference drug |
| JP6665740B2 (ja) * | 2016-09-13 | 2020-03-13 | 株式会社島津製作所 | ペプチド解析方法、ペプチド解析装置、及びペプチド解析用プログラム |
| CN110779979A (zh) * | 2019-10-09 | 2020-02-11 | 南昌大学 | 一种基于寡糖异构体组成差异鉴别蜂蜜糖浆掺假的方法 |
-
2021
- 2021-09-30 TW TW110136572A patent/TWI907533B/zh active
- 2021-09-30 WO PCT/US2021/052783 patent/WO2022072583A1/en not_active Ceased
- 2021-09-30 ES ES21807318T patent/ES3059573T3/es active Active
- 2021-09-30 EP EP21807318.7A patent/EP4222500B1/en active Active
- 2021-09-30 MX MX2023003862A patent/MX2023003862A/es unknown
- 2021-09-30 AU AU2021351498A patent/AU2021351498A1/en active Pending
- 2021-09-30 US US18/245,004 patent/US20230366889A1/en active Pending
- 2021-09-30 CN CN202180067521.7A patent/CN116348770A/zh active Pending
- 2021-09-30 JP JP2023519654A patent/JP2023546796A/ja active Pending
- 2021-09-30 CA CA3196920A patent/CA3196920A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4222500B1 (en) | 2025-11-12 |
| WO2022072583A1 (en) | 2022-04-07 |
| TWI907533B (zh) | 2025-12-11 |
| MX2023003862A (es) | 2023-04-14 |
| EP4222500C0 (en) | 2025-11-12 |
| CA3196920A1 (en) | 2022-04-07 |
| CN116348770A (zh) | 2023-06-27 |
| EP4222500A1 (en) | 2023-08-09 |
| TW202223377A (zh) | 2022-06-16 |
| ES3059573T3 (en) | 2026-03-23 |
| JP2023546796A (ja) | 2023-11-08 |
| AU2021351498A9 (en) | 2025-03-27 |
| US20230366889A1 (en) | 2023-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20250263773A1 (en) | Method for the determination of sequence variants of polypeptides | |
| Bogdanov et al. | Proteomics by FTICR mass spectrometry: top down and bottom up | |
| Resemann et al. | Full validation of therapeutic antibody sequences by middle-up mass measurements and middle-down protein sequencing | |
| Jansson | Strategies for analysis of isomeric peptides | |
| US20100015652A1 (en) | Antibody quantitation | |
| US20110111424A1 (en) | Analysis of ubiquitinated polypeptides | |
| Liu et al. | Quantitation of asparagine deamidation by isotope labeling and liquid chromatography coupled with mass spectrometry analysis | |
| EP4222500B1 (en) | Methods of detecting isoaspartic acid | |
| US11352418B2 (en) | Analysis of ubiquitinated polypeptides | |
| Wu et al. | Localizing Isomerized Residue Sites in Peptides with Tandem Mass Spectrometry | |
| Klapoetke et al. | Disulfide bond characterization of human factor Xa by mass spectrometry through protein-level partial reduction | |
| US20220326252A1 (en) | Electron transfer dissociation and mass spectrometry for improved protein sequencing of monoclonal antibodies | |
| CN114829927B (zh) | 用于质谱蛋白质分析的材料和方法 | |
| KR20170071849A (ko) | Lc-ms를 이용하는 항체 약물의 혈액 내 정량방법 | |
| KR20260042537A (ko) | 단백질 바이오마커를 정량화하기 위한 lc-ms/ms의 용도 | |
| Hessmann | Development of analytical strategies in quantitative proteomic: quantitation of host cell proteins by mass spectrometry as a quality control tool for the biopharmaceutical industry | |
| Gan | Salt Free HILIC-MS/MS as a Comprehensive and Complementary Site-Specific Glycosylation Tool in Therapeutic Proteins, Expanding Structural Resolution of Glycan Isomers | |
| Quanrud | Protein Isomerization in Aging Diseases: Mass Spectrometry Strategies for Identifying and Locating Isomerized Residues | |
| Gebelin | Development of high throughput proteomic and phosphoproteomic analytical methods and their application for pathologies' biomarker discovery on large cohorts | |
| Du et al. | MS Analysis of Biological Drugs, Proteins, and Peptides | |
| Liu | Development of methods for the analysis of protein post-translational modifications: isoaspartic acid and protein crosslinking. | |
| HK1177784A (en) | Method for the determination of sequence variants of polypeptides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SREP | Specification republished |