AU2021324883A1 - Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms - Google Patents
Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms Download PDFInfo
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- AU2021324883A1 AU2021324883A1 AU2021324883A AU2021324883A AU2021324883A1 AU 2021324883 A1 AU2021324883 A1 AU 2021324883A1 AU 2021324883 A AU2021324883 A AU 2021324883A AU 2021324883 A AU2021324883 A AU 2021324883A AU 2021324883 A1 AU2021324883 A1 AU 2021324883A1
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- bacterium
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- immunostimulatory
- immunostimulatory bacterium
- protein
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
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| US63/064,869 | 2020-08-12 | ||
| US202163188443P | 2021-05-13 | 2021-05-13 | |
| US17/320,200 US20220380720A1 (en) | 2019-11-12 | 2021-05-13 | Immunostimulatory bacteria delivery platforms and their use for delivery of therapeutic products |
| US63/188,443 | 2021-05-13 | ||
| US17/320,200 | 2021-05-13 | ||
| PCT/US2021/045832 WO2022036159A2 (en) | 2020-08-12 | 2021-08-12 | Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms |
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| MX (1) | MX2023001782A (https=) |
| WO (1) | WO2022036159A2 (https=) |
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| CN112852698B (zh) * | 2021-01-30 | 2022-11-29 | 军事科学院军事医学研究院军事兽医研究所 | 牛种布鲁氏菌A19株asd基因缺失株的构建方法和应用 |
| WO2023086796A2 (en) | 2021-11-09 | 2023-05-19 | Actym Therapeutics, Inc. | Immunostimulatory bacteria for converting macrophages into a phenotype amenable to treatment, and companion diagnostic for identifying subjects for treatment |
| EP4241790A1 (en) * | 2022-03-07 | 2023-09-13 | InnaTher Gene Therapy S.à.r.l. | Expression system for the treatment of cancer |
| EP4241791A1 (en) * | 2022-03-07 | 2023-09-13 | InnaTher Gene Therapy S.à.r.l. | Combined gene and radio therapy for the treatment of cancer |
| KR20240034391A (ko) * | 2022-09-07 | 2024-03-14 | 주식회사 젠라이프 | 폐암 진단용 전자코 센서 및 이를 이용한 폐암 진단용 전자코 시스템 |
| WO2024096123A1 (ja) * | 2022-11-04 | 2024-05-10 | 株式会社バイオパレット | 遺伝子が改変された微生物およびその生産方法 |
| CN115944722B (zh) * | 2023-01-09 | 2026-02-13 | 浙江大学 | 一种抗肿瘤mRNA疫苗及其制备方法和应用 |
| CN116312841B (zh) * | 2023-01-10 | 2026-03-31 | 中南大学 | 铁氧化物与金属微观结合形态的预测方法及其应用 |
| CN116212011B (zh) * | 2023-03-23 | 2025-10-10 | 华中科技大学 | 一种以细菌为载体的肿瘤个性化疫苗及其制备方法 |
| AU2024301594A1 (en) * | 2023-07-26 | 2026-01-08 | Cadmus Animal Health Limited | Rna vaccines for use in animal health |
| CN116676324B (zh) * | 2023-07-28 | 2023-10-27 | 四川大学华西医院 | 基于Kil蛋白构建释放抗肿瘤效应蛋白的系统及方法 |
| CN118436552B (zh) * | 2024-04-18 | 2024-11-26 | 梅晔生物医药股份有限公司 | 一种线粒体组合物及其应用、日化品 |
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| IL300447A (en) | 2023-04-01 |
| MX2023001782A (es) | 2023-05-22 |
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| CA3191433A1 (en) | 2022-02-17 |
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| WO2022036159A3 (en) | 2022-04-14 |
| JP2023539454A (ja) | 2023-09-14 |
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