AU2021263745A1 - Methods of in vitro cell delivery - Google Patents

Methods of in vitro cell delivery Download PDF

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Publication number
AU2021263745A1
AU2021263745A1 AU2021263745A AU2021263745A AU2021263745A1 AU 2021263745 A1 AU2021263745 A1 AU 2021263745A1 AU 2021263745 A AU2021263745 A AU 2021263745A AU 2021263745 A AU2021263745 A AU 2021263745A AU 2021263745 A1 AU2021263745 A1 AU 2021263745A1
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Australia
Prior art keywords
methods
vitro cell
cell delivery
delivery
vitro
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Pending
Application number
AU2021263745A
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English (en)
Inventor
Mohamed Simo ARREDOUANI
Sean Michael BURNS
Paula GUTIERREZ MARTINEZ
Arti Mahendra Prakash KANJOLIA
Özgün KILIÇ
Reed Walker LARIVIERE
Anthony Monti
Pooja Kyatsandra NARENDRA
Aaron PRODEUS
Palak Sushil SHARMA
Eleni Stampouloglou
Qingzhan ZHANG
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Intellia Therapeutics Inc
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Intellia Therapeutics Inc
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Publication of AU2021263745A1 publication Critical patent/AU2021263745A1/en
Pending legal-status Critical Current

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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/14—Blood; Artificial blood
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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AU2021263745A 2020-04-28 2021-04-27 Methods of in vitro cell delivery Pending AU2021263745A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202063016913P 2020-04-28 2020-04-28
US63/016,913 2020-04-28
US202063121781P 2020-12-04 2020-12-04
US63/121,781 2020-12-04
US202063124058P 2020-12-11 2020-12-11
US63/124,058 2020-12-11
US202063130100P 2020-12-23 2020-12-23
US63/130,100 2020-12-23
US202163165619P 2021-03-24 2021-03-24
US63/165,619 2021-03-24
US202163176221P 2021-04-17 2021-04-17
US63/176,221 2021-04-17
PCT/US2021/029446 WO2021222287A2 (en) 2020-04-28 2021-04-27 Methods of in vitro cell delivery

Publications (1)

Publication Number Publication Date
AU2021263745A1 true AU2021263745A1 (en) 2022-12-08

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AU2021263745A Pending AU2021263745A1 (en) 2020-04-28 2021-04-27 Methods of in vitro cell delivery

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US (1) US20230183753A1 (https=)
EP (1) EP4143304A2 (https=)
JP (1) JP2023524666A (https=)
KR (1) KR20230017783A (https=)
CN (1) CN116018403A (https=)
AU (1) AU2021263745A1 (https=)
BR (1) BR112022021676A2 (https=)
CA (1) CA3181340A1 (https=)
CL (1) CL2022002974A1 (https=)
IL (1) IL297550A (https=)
MX (1) MX2022013403A (https=)
TW (1) TW202204612A (https=)
WO (1) WO2021222287A2 (https=)

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JP2023549011A (ja) 2020-09-15 2023-11-22 ヴァーヴ・セラピューティクス，インコーポレーテッド 遺伝子編集のための脂質製剤
IL303195A (en) 2020-11-25 2023-07-01 Akagera Medicines Inc Lipid nanoparticles for delivery of nucleic acids and related methods of use
AU2021409732A1 (en) * 2020-12-23 2023-07-20 Intellia Therapeutics, Inc. Compositions and methods for reducing hla-a in a cell
JP2024505672A (ja) 2021-02-08 2024-02-07 インテリア セラピューティクス，インコーポレイテッド 免疫療法のためのナチュラルキラー細胞受容体２ｂ４組成物及び方法
WO2022170194A2 (en) 2021-02-08 2022-08-11 Intellia Therapeutics, Inc. Lymphocyte activation gene 3 (lag3) compositions and methods for immunotherapy
JP2024506016A (ja) 2021-02-08 2024-02-08 インテリア セラピューティクス，インコーポレイテッド 免疫療法のためのｔ細胞免疫グロブリン及びムチンドメイン３（ｔｉｍ３）組成物及び方法
KR20240032013A (ko) 2021-06-10 2024-03-08 인텔리아 테라퓨틱스, 인크. 유전자 편집을 위한 내부 링커를 포함하는 변형된 가이드 rna
WO2023274386A1 (zh) * 2021-07-01 2023-01-05 宁波茂行生物医药科技有限公司 靶向egfr的通用型car-t细胞及其制备方法
EP4392060A1 (en) 2021-08-24 2024-07-03 Intellia Therapeutics, Inc. Programmed cell death protein 1 (pd1) compositions and methods for cell-based therapy
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