AU2021250704A1 - Influenza vaccines - Google Patents

Influenza vaccines Download PDF

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Publication number
AU2021250704A1
AU2021250704A1 AU2021250704A AU2021250704A AU2021250704A1 AU 2021250704 A1 AU2021250704 A1 AU 2021250704A1 AU 2021250704 A AU2021250704 A AU 2021250704A AU 2021250704 A AU2021250704 A AU 2021250704A AU 2021250704 A1 AU2021250704 A1 AU 2021250704A1
Authority
AU
Australia
Prior art keywords
amino acid
seq
polypeptide
nucleic acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021250704A
Other languages
English (en)
Inventor
George CARNELL
Matteo Ferrari
Jonathan Luke Heeney
Sneha VISHWANATH
David Wells
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge Enterprise Ltd
Diosynvax Ltd
Original Assignee
Cambridge Enterprise Ltd
Diosynvax Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Enterprise Ltd, Diosynvax Ltd filed Critical Cambridge Enterprise Ltd
Publication of AU2021250704A1 publication Critical patent/AU2021250704A1/en
Assigned to CAMBRIDGE ENTERPRISE LIMITED, DIOSYNVAX LTD reassignment CAMBRIDGE ENTERPRISE LIMITED Request for Assignment Assignors: DIOSYNVAX LTD, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2021250704A 2020-04-01 2021-04-01 Influenza vaccines Pending AU2021250704A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2004825.2 2020-04-01
GBGB2004825.2A GB202004825D0 (en) 2020-04-01 2020-04-01 Influenza vaccines
PCT/GB2021/050825 WO2021198701A1 (en) 2020-04-01 2021-04-01 Influenza vaccines

Publications (1)

Publication Number Publication Date
AU2021250704A1 true AU2021250704A1 (en) 2022-12-08

Family

ID=70553229

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021250704A Pending AU2021250704A1 (en) 2020-04-01 2021-04-01 Influenza vaccines

Country Status (8)

Country Link
US (1) US20230149530A1 (https=)
EP (1) EP4126026A1 (https=)
JP (1) JP2023522154A (https=)
CN (1) CN116457005A (https=)
AU (1) AU2021250704A1 (https=)
CA (1) CA3179035A1 (https=)
GB (1) GB202004825D0 (https=)
WO (1) WO2021198701A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114395052B (zh) * 2022-03-25 2022-07-22 北京中海生物科技有限公司 一种重组禽流感三价疫苗及其制备方法与应用
GB202315888D0 (en) * 2023-10-17 2023-11-29 Diosynvax Ltd Influenza vaccines
CN117912568B (zh) * 2024-01-05 2024-08-06 中山大学 H9n2亚型禽流感毒株抗原性快速鉴别方法及装置
WO2025179103A1 (en) * 2024-02-23 2025-08-28 University Of Georgia Research Foundation, Inc. Pentavalent and octavalent influenza virus immunogens, compositions and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883171B2 (en) * 2010-09-14 2014-11-11 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for influenza
AR083533A1 (es) * 2010-10-22 2013-03-06 Boehringer Ingelheim Vetmed Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe
CN102140441B (zh) * 2010-11-04 2013-12-18 高福 基于减毒痘苗病毒天坛株为载体的禽流感疫苗
CN103221064B (zh) * 2011-11-23 2014-12-03 苏州工业园区唯可达生物科技有限公司 抗流感病毒的免疫方法及其组合疫苗
CA2863949C (en) * 2012-02-13 2021-06-29 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Computationally optimized broadly reactive antigens for human and avian h5n1 influenza
WO2013185177A1 (en) * 2012-06-12 2013-12-19 Csl Limited Influenza vaccine
US20140286981A1 (en) * 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
CN106029686B (zh) * 2013-12-23 2019-09-10 淡马锡生命科学研究院有限公司 单价h5疫苗
EA035375B1 (ru) * 2014-07-10 2020-06-03 Янссен Вэксинс Энд Превеншн Б.В. Вакцины против вируса гриппа и их применения
WO2016100926A1 (en) * 2014-12-19 2016-06-23 Oregon Health & Science University Synergistic co-administration of computationally optimized broadly reactive antigens for human and avian h5n1 influenza
EP3463447A4 (en) * 2016-06-03 2020-05-27 Icahn School of Medicine at Mount Sinai INFLUENZA VIRUS PROTECTION Vaccines
JP2024537250A (ja) * 2021-10-06 2024-10-10 ディオシンバックス リミテッド インフルエンザワクチン

Also Published As

Publication number Publication date
CA3179035A1 (en) 2021-10-07
JP2023522154A (ja) 2023-05-29
GB202004825D0 (en) 2020-05-13
CN116457005A (zh) 2023-07-18
US20230149530A1 (en) 2023-05-18
EP4126026A1 (en) 2023-02-08
WO2021198701A1 (en) 2021-10-07

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: DIOSYNVAX LTD

Free format text: FORMER APPLICANT(S): DIOSYNVAX LTD; THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

Owner name: CAMBRIDGE ENTERPRISE LIMITED

Free format text: FORMER APPLICANT(S): DIOSYNVAX LTD; THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE