JP2023522154A - インフルエンザワクチン - Google Patents

インフルエンザワクチン Download PDF

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Publication number
JP2023522154A
JP2023522154A JP2022560280A JP2022560280A JP2023522154A JP 2023522154 A JP2023522154 A JP 2023522154A JP 2022560280 A JP2022560280 A JP 2022560280A JP 2022560280 A JP2022560280 A JP 2022560280A JP 2023522154 A JP2023522154 A JP 2023522154A
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Japan
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amino acid
seq
polypeptide
nucleic acid
acid sequence
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JP2022560280A
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Japanese (ja)
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JP2023522154A5 (https=
Inventor
ジョナサン ルーク ヒーニー，
スネハ ビシュワナス，
ジョージ カーネル，
デイビッド ウェルズ，
マッテオ フェラーリ，
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Chancellor masters And Scholars Of University Of Cambridge
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Chancellor masters And Scholars Of University Of Cambridge
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Application filed by Chancellor masters And Scholars Of University Of Cambridge filed Critical Chancellor masters And Scholars Of University Of Cambridge
Publication of JP2023522154A publication Critical patent/JP2023522154A/ja
Publication of JP2023522154A5 publication Critical patent/JP2023522154A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2022560280A 2020-04-01 2021-04-01 インフルエンザワクチン Pending JP2023522154A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2004825.2 2020-04-01
GBGB2004825.2A GB202004825D0 (en) 2020-04-01 2020-04-01 Influenza vaccines
PCT/GB2021/050825 WO2021198701A1 (en) 2020-04-01 2021-04-01 Influenza vaccines

Publications (2)

Publication Number Publication Date
JP2023522154A true JP2023522154A (ja) 2023-05-29
JP2023522154A5 JP2023522154A5 (https=) 2024-05-08

Family

ID=70553229

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022560280A Pending JP2023522154A (ja) 2020-04-01 2021-04-01 インフルエンザワクチン

Country Status (8)

Country Link
US (1) US20230149530A1 (https=)
EP (1) EP4126026A1 (https=)
JP (1) JP2023522154A (https=)
CN (1) CN116457005A (https=)
AU (1) AU2021250704A1 (https=)
CA (1) CA3179035A1 (https=)
GB (1) GB202004825D0 (https=)
WO (1) WO2021198701A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114395052B (zh) * 2022-03-25 2022-07-22 北京中海生物科技有限公司 一种重组禽流感三价疫苗及其制备方法与应用
GB202315888D0 (en) * 2023-10-17 2023-11-29 Diosynvax Ltd Influenza vaccines
CN117912568B (zh) * 2024-01-05 2024-08-06 中山大学 H9n2亚型禽流感毒株抗原性快速鉴别方法及装置
WO2025179103A1 (en) * 2024-02-23 2025-08-28 University Of Georgia Research Foundation, Inc. Pentavalent and octavalent influenza virus immunogens, compositions and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102140441A (zh) * 2010-11-04 2011-08-03 高福 基于减毒痘苗病毒天坛株为载体的禽流感疫苗
WO2012036993A1 (en) * 2010-09-14 2012-03-22 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Computationally optimized broadly reactive antigens for influenza
WO2013075266A1 (en) * 2011-11-23 2013-05-30 Vacdiagn Biotechnology Co., Ltd. Immune methods against influenza viruses and combinatorial vaccines thereof
WO2015099609A1 (en) * 2013-12-23 2015-07-02 Temasek Life Sciences Laboratory Limited Monovalent h5 vaccine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR083533A1 (es) * 2010-10-22 2013-03-06 Boehringer Ingelheim Vetmed Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe
CA2863949C (en) * 2012-02-13 2021-06-29 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Computationally optimized broadly reactive antigens for human and avian h5n1 influenza
WO2013185177A1 (en) * 2012-06-12 2013-12-19 Csl Limited Influenza vaccine
US20140286981A1 (en) * 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
EA035375B1 (ru) * 2014-07-10 2020-06-03 Янссен Вэксинс Энд Превеншн Б.В. Вакцины против вируса гриппа и их применения
WO2016100926A1 (en) * 2014-12-19 2016-06-23 Oregon Health & Science University Synergistic co-administration of computationally optimized broadly reactive antigens for human and avian h5n1 influenza
EP3463447A4 (en) * 2016-06-03 2020-05-27 Icahn School of Medicine at Mount Sinai INFLUENZA VIRUS PROTECTION Vaccines
JP2024537250A (ja) * 2021-10-06 2024-10-10 ディオシンバックス リミテッド インフルエンザワクチン

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012036993A1 (en) * 2010-09-14 2012-03-22 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Computationally optimized broadly reactive antigens for influenza
CN102140441A (zh) * 2010-11-04 2011-08-03 高福 基于减毒痘苗病毒天坛株为载体的禽流感疫苗
WO2013075266A1 (en) * 2011-11-23 2013-05-30 Vacdiagn Biotechnology Co., Ltd. Immune methods against influenza viruses and combinatorial vaccines thereof
WO2015099609A1 (en) * 2013-12-23 2015-07-02 Temasek Life Sciences Laboratory Limited Monovalent h5 vaccine

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK，ACCESSION NO. ADM33956，[ONLINE], JPN6025012505, 30 August 2010 (2010-08-30), ISSN: 0005561048 *
DATABASE GENBANK，ACCESSION NO. AEQ50042，[ONLINE], JPN6025012507, 29 November 2011 (2011-11-29), ISSN: 0005561050 *
DATABASE GENBANK，ACCESSION NO. AKH14272，[ONLINE], JPN6025012506, 19 May 2015 (2015-05-19), ISSN: 0005561049 *
J. VIROL., vol. 84, no. 17, JPN6025012504, 2010, pages 8389 - 8397, ISSN: 0005561047 *
VIRUS GENES, vol. 44, JPN6025012503, 2012, pages 247 - 252, ISSN: 0005561046 *

Also Published As

Publication number Publication date
AU2021250704A1 (en) 2022-12-08
CA3179035A1 (en) 2021-10-07
GB202004825D0 (en) 2020-05-13
CN116457005A (zh) 2023-07-18
US20230149530A1 (en) 2023-05-18
EP4126026A1 (en) 2023-02-08
WO2021198701A1 (en) 2021-10-07

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