AU2020408371A1 - Sensor for detecting a bioanalyte and a method for the detection thereof - Google Patents

Sensor for detecting a bioanalyte and a method for the detection thereof Download PDF

Info

Publication number
AU2020408371A1
AU2020408371A1 AU2020408371A AU2020408371A AU2020408371A1 AU 2020408371 A1 AU2020408371 A1 AU 2020408371A1 AU 2020408371 A AU2020408371 A AU 2020408371A AU 2020408371 A AU2020408371 A AU 2020408371A AU 2020408371 A1 AU2020408371 A1 AU 2020408371A1
Authority
AU
Australia
Prior art keywords
bioanalyte
binding
oxygen
metal oxide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020408371A
Other languages
English (en)
Inventor
Taimur Ahmed
Madhu BHASKARAN
Mortiz DOERING
Ganganath Perera
Sharath SRIRAM
Sumeet WALIA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Royal Melbourne Institute of Technology
Original Assignee
Royal Melbourne Institute of Technology Ltd
Melbourne Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2019904865A external-priority patent/AU2019904865A0/en
Application filed by Royal Melbourne Institute of Technology Ltd, Melbourne Institute of Technology filed Critical Royal Melbourne Institute of Technology Ltd
Publication of AU2020408371A1 publication Critical patent/AU2020408371A1/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Inorganic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
AU2020408371A 2019-12-20 2020-12-18 Sensor for detecting a bioanalyte and a method for the detection thereof Pending AU2020408371A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019904865A AU2019904865A0 (en) 2019-12-20 Sensor for detecting a bioanalyte and a method for the detection thereof
AU2019904865 2019-12-20
PCT/AU2020/051396 WO2021119755A1 (en) 2019-12-20 2020-12-18 Sensor for detecting a bioanalyte and a method for the detection thereof

Publications (1)

Publication Number Publication Date
AU2020408371A1 true AU2020408371A1 (en) 2022-07-21

Family

ID=76476458

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020408371A Pending AU2020408371A1 (en) 2019-12-20 2020-12-18 Sensor for detecting a bioanalyte and a method for the detection thereof

Country Status (8)

Country Link
US (1) US20230045427A1 (https=)
EP (1) EP4078182A4 (https=)
JP (1) JP7644992B2 (https=)
KR (1) KR20220117326A (https=)
CN (1) CN115023613B (https=)
AU (1) AU2020408371A1 (https=)
CA (1) CA3162465A1 (https=)
WO (1) WO2021119755A1 (https=)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002031598A (ja) * 2000-05-11 2002-01-31 Toto Ltd センサ素子の製造方法
US6737286B2 (en) * 2001-11-30 2004-05-18 Arizona Board Of Regents Apparatus and method for fabricating arrays of atomic-scale contacts and gaps between electrodes and applications thereof
GB2420180A (en) * 2004-11-11 2006-05-17 Sensor Tech Ltd Method of electrochemical analysis of an analyte
US20100143887A1 (en) * 2008-12-05 2010-06-10 Electronics And Telecommunications Research Institute Biosensor and method for detecting biomolecules by using the biosensor
KR101191386B1 (ko) * 2008-12-19 2012-10-15 한국전자통신연구원 센서용 산화물 반도체 나노섬유 제조 방법 및 그를 이용한 가스 센서
US20100216256A1 (en) * 2009-02-17 2010-08-26 Florida State University Research Foundation Nanobelt-based sensors and detection methods
AU2010256333B2 (en) * 2009-06-01 2013-04-04 Rmit University Electrodeposited gold nanostructures
JP5331952B2 (ja) * 2009-06-08 2013-10-30 哲彌 逢坂 固定化方法及びセンシング方法
US9318614B2 (en) * 2012-08-02 2016-04-19 Cbrite Inc. Self-aligned metal oxide TFT with reduced number of masks and with reduced power consumption
US9064965B2 (en) * 2012-02-24 2015-06-23 Rutgers, The State University Of New Jersey Zinc oxide-based thin film transistor biosensors with high sensitivity and selectivity
GB201207585D0 (en) * 2012-05-01 2012-06-13 Isis Innovation An electrode and use thereof
EP2833129B1 (en) * 2013-07-30 2019-10-09 Sensirion AG Method and apparatus for analyzing a gas by a conductance-type particulate metal-oxide gas sensor
US9702847B2 (en) * 2014-12-30 2017-07-11 Avails Medical, Inc. Systems and methods for detecting a substance in bodily fluid
WO2017088016A1 (en) * 2015-11-24 2017-06-01 Rmit University A memristor device and a method of fabrication thereof
GB2548888A (en) * 2016-03-31 2017-10-04 Cambridge Display Tech Ltd Sensor, method of forming a sensor and use thereof
US9976952B2 (en) * 2016-06-03 2018-05-22 Rmit University Flexible or stretchable sensor for use in detecting a substance and/or electromagnetic radiation, and a method for detecting thereof
JP6782968B2 (ja) * 2016-08-26 2020-11-11 国立大学法人東京海洋大学 電極およびバイオセンサ
KR102861875B1 (ko) * 2018-01-04 2025-09-19 라이텐, 인코포레이티드 공진 가스 센서

Also Published As

Publication number Publication date
JP2023507206A (ja) 2023-02-21
EP4078182A1 (en) 2022-10-26
CN115023613A (zh) 2022-09-06
CA3162465A1 (en) 2021-06-24
EP4078182A4 (en) 2023-12-27
US20230045427A1 (en) 2023-02-09
CN115023613B (zh) 2026-04-03
WO2021119755A1 (en) 2021-06-24
KR20220117326A (ko) 2022-08-23
JP7644992B2 (ja) 2025-03-13

Similar Documents

Publication Publication Date Title
Hwang et al. High sensitive and selective electrochemical biosensor: Label-free detection of human norovirus using affinity peptide as molecular binder
Sharma et al. Ultrasensitive direct impedimetric immunosensor for detection of serum HER2
DK2556090T3 (en) Soluble, human st-2 antibodies and assays
CN104067130B (zh) 肾上腺髓质素测定与用于确定成熟肾上腺髓质素的方法
US7329536B2 (en) Piezoimmunosensor
KR20140143140A (ko) 피분석물을 검출 및 측정하기 위한 방법 및 장치
JP2018504612A (ja) 検体を検出するためのデバイス、システム、及び方法
Gao et al. Graphene transistor arrays functionalized with genetically engineered antibody fragments for Lyme disease diagnosis
CN110546506B (zh) 改进的免疫原性测定法
KR102043321B1 (ko) 빗살형 전극에 나노입자을 증착시켜 TNF-alpha 측정 감도를 높인 나노바이오센서
Weeraratne et al. Development of a biosensor-based immunogenicity assay capable of blocking soluble drug target interference
CN105793709B (zh) 用于使用半抗原和结合所述半抗原的抗体作为参照抗体的免疫测量的方法，以及用于使用所述参照抗体的免疫测量的装置
Thangsunan et al. Affimer-based impedimetric biosensors for fibroblast growth factor receptor 3 (FGFR3): a novel tool for detection and surveillance of recurrent bladder cancer
Kim et al. Detection of IFN-γ for latent tuberculosis diagnosis using an anodized aluminum oxide-based capacitive sensor
EP3362785A1 (en) Electrochemical assay for a protein analyte
US20230045427A1 (en) Sensor for detecting a bioanalyte and a method for the detection thereof
Shang et al. Immobilization of a human epidermal growth factor receptor 2 mimotope-derived synthetic peptide on Au and its potential application for detection of herceptin in human serum by quartz crystal microbalance
Nunez et al. Electrochemical immunosensor for antibody recognition against SARS-CoV-2 B-cell epitope: impact of RBD mutations on antigen–antibody binding
CN103874925A (zh) 根据乳胶凝集法检测基质金属蛋白酶-3的方法
US20240295517A1 (en) Conductometric sensor for detecting a bioanalyte and a method for the detection thereof
CN114088793A (zh) 一种有机电化学晶体管传感器及其制备方法与应用
WO2016127278A1 (zh) 尿液补体c3蛋白的应用
Arora et al. An impedimetric response study for the efficient detection of breast cancer specific biomarker CA 15-3 using a tin oxide thin film based immunoelectrode
JP2026503940A (ja) アルツハイマー病のバイオマーカーを検出するためのバイオセンサを製造する方法およびそれによって製造されたバイオセンサ
Shang et al. Immobilization of a HER2 mimotope-derived synthetic peptide on Au and its potential application for detection of herceptin in human serum by QCM