JP7644992B2 - 生体分析物を検出するためのセンサおよびその検出方法 - Google Patents

生体分析物を検出するためのセンサおよびその検出方法 Download PDF

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Publication number
JP7644992B2
JP7644992B2 JP2022538215A JP2022538215A JP7644992B2 JP 7644992 B2 JP7644992 B2 JP 7644992B2 JP 2022538215 A JP2022538215 A JP 2022538215A JP 2022538215 A JP2022538215 A JP 2022538215A JP 7644992 B2 JP7644992 B2 JP 7644992B2
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binding
bioanalyte
sensor
metal oxide
oxygen
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JP2023507206A5 (https=
JP2023507206A (ja
Inventor
アハメド，タイムール
デーリング，モリッツ
ペレラ，ガンガナート
ワリア，スミート
バースカラン，マドゥー
スリラム，シャラート
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Royal Melbourne Institute of Technology
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Royal Melbourne Institute of Technology Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Inorganic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
JP2022538215A 2019-12-20 2020-12-18 生体分析物を検出するためのセンサおよびその検出方法 Active JP7644992B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019904865A AU2019904865A0 (en) 2019-12-20 Sensor for detecting a bioanalyte and a method for the detection thereof
AU2019904865 2019-12-20
PCT/AU2020/051396 WO2021119755A1 (en) 2019-12-20 2020-12-18 Sensor for detecting a bioanalyte and a method for the detection thereof

Publications (3)

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JP2023507206A JP2023507206A (ja) 2023-02-21
JP2023507206A5 JP2023507206A5 (https=) 2024-10-10
JP7644992B2 true JP7644992B2 (ja) 2025-03-13

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JP2022538215A Active JP7644992B2 (ja) 2019-12-20 2020-12-18 生体分析物を検出するためのセンサおよびその検出方法

Country Status (8)

Country Link
US (1) US20230045427A1 (https=)
EP (1) EP4078182A4 (https=)
JP (1) JP7644992B2 (https=)
KR (1) KR20220117326A (https=)
CN (1) CN115023613B (https=)
AU (1) AU2020408371A1 (https=)
CA (1) CA3162465A1 (https=)
WO (1) WO2021119755A1 (https=)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002031598A (ja) 2000-05-11 2002-01-31 Toto Ltd センサ素子の製造方法
JP2010133948A (ja) 2008-12-05 2010-06-17 Korea Electronics Telecommun バイオセンサ及びこれを利用したバイオ分子検出方法
US20100216256A1 (en) 2009-02-17 2010-08-26 Florida State University Research Foundation Nanobelt-based sensors and detection methods
JP2010281769A (ja) 2009-06-08 2010-12-16 Waseda Univ 固定化方法及びセンシング方法
JP2015516066A (ja) 2012-05-01 2015-06-04 アイシス イノベーション リミテッド 電極およびその使用
JP2018500537A (ja) 2014-12-30 2018-01-11 アバイルズ メディカル，インコーポレイテッド 体液中の物質を検出するシステム及び方法
JP2018031740A (ja) 2016-08-26 2018-03-01 国立大学法人東京海洋大学 電極およびバイオセンサ

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US6737286B2 (en) * 2001-11-30 2004-05-18 Arizona Board Of Regents Apparatus and method for fabricating arrays of atomic-scale contacts and gaps between electrodes and applications thereof
GB2420180A (en) * 2004-11-11 2006-05-17 Sensor Tech Ltd Method of electrochemical analysis of an analyte
KR101191386B1 (ko) * 2008-12-19 2012-10-15 한국전자통신연구원 센서용 산화물 반도체 나노섬유 제조 방법 및 그를 이용한 가스 센서
AU2010256333B2 (en) * 2009-06-01 2013-04-04 Rmit University Electrodeposited gold nanostructures
US9318614B2 (en) * 2012-08-02 2016-04-19 Cbrite Inc. Self-aligned metal oxide TFT with reduced number of masks and with reduced power consumption
US9064965B2 (en) * 2012-02-24 2015-06-23 Rutgers, The State University Of New Jersey Zinc oxide-based thin film transistor biosensors with high sensitivity and selectivity
EP2833129B1 (en) * 2013-07-30 2019-10-09 Sensirion AG Method and apparatus for analyzing a gas by a conductance-type particulate metal-oxide gas sensor
WO2017088016A1 (en) * 2015-11-24 2017-06-01 Rmit University A memristor device and a method of fabrication thereof
GB2548888A (en) * 2016-03-31 2017-10-04 Cambridge Display Tech Ltd Sensor, method of forming a sensor and use thereof
US9976952B2 (en) * 2016-06-03 2018-05-22 Rmit University Flexible or stretchable sensor for use in detecting a substance and/or electromagnetic radiation, and a method for detecting thereof
KR102861875B1 (ko) * 2018-01-04 2025-09-19 라이텐, 인코포레이티드 공진 가스 센서

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002031598A (ja) 2000-05-11 2002-01-31 Toto Ltd センサ素子の製造方法
JP2010133948A (ja) 2008-12-05 2010-06-17 Korea Electronics Telecommun バイオセンサ及びこれを利用したバイオ分子検出方法
US20100216256A1 (en) 2009-02-17 2010-08-26 Florida State University Research Foundation Nanobelt-based sensors and detection methods
JP2010281769A (ja) 2009-06-08 2010-12-16 Waseda Univ 固定化方法及びセンシング方法
JP2015516066A (ja) 2012-05-01 2015-06-04 アイシス イノベーション リミテッド 電極およびその使用
JP2018500537A (ja) 2014-12-30 2018-01-11 アバイルズ メディカル，インコーポレイテッド 体液中の物質を検出するシステム及び方法
JP2018031740A (ja) 2016-08-26 2018-03-01 国立大学法人東京海洋大学 電極およびバイオセンサ

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chidambaram et al.，Versatile conductometoric biosensors for rapid and selective detection of inflammatory and cardiac biomarkers in saliva，Biosensors and Bioelectronics，Vol.261 Art.116516，2024年06月20日
JACOBS et al.，Ultra-sensitive electrical immunoassay biosensors using nanotextured zinc oxide thin films on printed circuit borad platforms，Biosensors and Bioelectronics，Vol.55 No.2014，2013年11月28日，p.7-13

Also Published As

Publication number Publication date
AU2020408371A1 (en) 2022-07-21
JP2023507206A (ja) 2023-02-21
EP4078182A1 (en) 2022-10-26
CN115023613A (zh) 2022-09-06
CA3162465A1 (en) 2021-06-24
EP4078182A4 (en) 2023-12-27
US20230045427A1 (en) 2023-02-09
CN115023613B (zh) 2026-04-03
WO2021119755A1 (en) 2021-06-24
KR20220117326A (ko) 2022-08-23

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