AU2020316516A1 - Chimeric antigen receptors with MAGE-A4 specificity and uses thereof - Google Patents

Chimeric antigen receptors with MAGE-A4 specificity and uses thereof Download PDF

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Publication number
AU2020316516A1
AU2020316516A1 AU2020316516A AU2020316516A AU2020316516A1 AU 2020316516 A1 AU2020316516 A1 AU 2020316516A1 AU 2020316516 A AU2020316516 A AU 2020316516A AU 2020316516 A AU2020316516 A AU 2020316516A AU 2020316516 A1 AU2020316516 A1 AU 2020316516A1
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Prior art keywords
mage
seq
amino acid
acid sequence
cell
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AU2020316516A
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Kevin BRAY
Frank DELFINO
David DILILLO
Thomas Craig Meagher
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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AU2020316516A 2019-07-24 2020-07-24 Chimeric antigen receptors with MAGE-A4 specificity and uses thereof Pending AU2020316516A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962878125P 2019-07-24 2019-07-24
US62/878,125 2019-07-24
US202063020177P 2020-05-05 2020-05-05
US63/020,177 2020-05-05
US202063021407P 2020-05-07 2020-05-07
US63/021,407 2020-05-07
PCT/US2020/043567 WO2021016585A1 (en) 2019-07-24 2020-07-24 Chimeric antigen receptors with mage-a4 specificity and uses thereof

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AU2020316516A1 true AU2020316516A1 (en) 2022-02-17

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US (1) US12600793B2 (https=)
EP (1) EP4004049A1 (https=)
JP (1) JP7721500B2 (https=)
KR (1) KR20220038397A (https=)
CN (1) CN114174345B (https=)
AU (1) AU2020316516A1 (https=)
BR (1) BR112022001194A2 (https=)
CA (1) CA3147903A1 (https=)
CL (1) CL2022000130A1 (https=)
CO (1) CO2022000451A2 (https=)
IL (1) IL289820A (https=)
MX (1) MX2022000896A (https=)
PH (1) PH12022550102A1 (https=)
WO (1) WO2021016585A1 (https=)

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KR20210104772A (ko) 2018-12-14 2021-08-25 블루버드 바이오, 인코포레이티드. 이량체화제로 조절된 면역수용체 복합체
JP7674278B2 (ja) 2019-07-03 2025-05-09 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 抗ニューヨーク食道扁平上皮がん１（ｎｙ－ｅｓｏ－１）抗原結合タンパク質およびその使用方法
EP4004049A1 (en) 2019-07-24 2022-06-01 Regeneron Pharmaceuticals, Inc. Chimeric antigen receptors with mage-a4 specificity and uses thereof
KR20230025662A (ko) 2020-05-05 2023-02-22 리제너론 파마슈티칼스 인코포레이티드 Cd28 제타 및 cd3 제타를 포함하는 car
MX2023010541A (es) * 2021-03-09 2023-11-24 Cdr Life Ag Proteinas de union al antigeno del peptido del mhc mage-a4.
US12435444B2 (en) 2021-03-09 2025-10-07 Cdr-Life Ag Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same
AU2022271212A1 (en) * 2021-05-04 2023-11-30 Regeneron Pharmaceuticals, Inc. Chimeric antigen receptors with mage-a4 specificity and uses thereof
JP2024525727A (ja) * 2021-07-14 2024-07-12 ２セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたｔ細胞受容体
IL310057A (en) * 2021-07-21 2024-03-01 Immunitybio Inc Generation of chimeric antigen receptor mRNA molecules for expression in primary NK cells
CA3264474A1 (en) * 2022-09-14 2024-03-21 Cdr-Life Ag MAGE-A4 DOUBLE T LYMPHOCYTE ENGAGEMENT

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