AU2020220637A1 - Decorated inclusion body and uses thereof - Google Patents

Decorated inclusion body and uses thereof Download PDF

Info

Publication number
AU2020220637A1
AU2020220637A1 AU2020220637A AU2020220637A AU2020220637A1 AU 2020220637 A1 AU2020220637 A1 AU 2020220637A1 AU 2020220637 A AU2020220637 A AU 2020220637A AU 2020220637 A AU2020220637 A AU 2020220637A AU 2020220637 A1 AU2020220637 A1 AU 2020220637A1
Authority
AU
Australia
Prior art keywords
peptide
inclusion body
spytag
protein
partner
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2020220637A
Other languages
English (en)
Inventor
Wouter Simon Petrus Jong
Joen Luirink
Hendrik Bart VAN DEN BERG VAN SAPAROEA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abera Bioscience AB
Original Assignee
Abera Bioscience AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abera Bioscience AB filed Critical Abera Bioscience AB
Publication of AU2020220637A1 publication Critical patent/AU2020220637A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2020220637A 2019-02-15 2020-02-14 Decorated inclusion body and uses thereof Abandoned AU2020220637A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19157490.4 2019-02-15
EP19157490 2019-02-15
PCT/EP2020/053933 WO2020165425A1 (en) 2019-02-15 2020-02-14 Decorated inclusion body and uses thereof

Publications (1)

Publication Number Publication Date
AU2020220637A1 true AU2020220637A1 (en) 2021-10-07

Family

ID=65686666

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020220637A Abandoned AU2020220637A1 (en) 2019-02-15 2020-02-14 Decorated inclusion body and uses thereof

Country Status (7)

Country Link
US (1) US20220064691A1 (https=)
EP (1) EP3923968A1 (https=)
JP (1) JP2022520550A (https=)
CN (1) CN113347988A (https=)
AU (1) AU2020220637A1 (https=)
CA (1) CA3130159A1 (https=)
WO (1) WO2020165425A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112062856A (zh) * 2020-09-16 2020-12-11 华侨大学 一种共价捕获目标蛋白的磁性载体制备方法
EP4408461A1 (en) * 2021-09-30 2024-08-07 AdaptVac ApS Methods and particles for modulating an immune response
CN117264081B (zh) * 2023-11-21 2025-03-21 华南理工大学 一种双肽受体激动剂及其制备方法与应用
CN117866110B (zh) * 2023-12-27 2024-06-11 广东唯泰生物科技有限公司 一种靶向flt-3的第四代嵌合抗原受体及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578308A (en) 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
GB201002362D0 (en) 2010-02-11 2010-03-31 Isis Innovation Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds
CN104884084B (zh) 2012-09-26 2018-05-22 Fvg有限公司 鱼用亚单位浸泡疫苗
WO2018138316A1 (en) 2017-01-27 2018-08-02 Abera Bioscience Ab New compositions, methods and uses
WO2018162450A1 (en) * 2017-03-06 2018-09-13 Fundación Para La Investigación Médica Aplicada New inmunostimulatory compositions comprising an entity of cold inducible rna-binding protein with an antigen for the activation of dendritic cells

Also Published As

Publication number Publication date
JP2022520550A (ja) 2022-03-31
US20220064691A1 (en) 2022-03-03
EP3923968A1 (en) 2021-12-22
CA3130159A1 (en) 2020-08-20
WO2020165425A1 (en) 2020-08-20
CN113347988A (zh) 2021-09-03

Similar Documents

Publication Publication Date Title
JP7054948B2 (ja) プロテアーゼ切断耐性、志賀毒素aサブユニットエフェクターポリペプチド及びそれを含む細胞標的化分子
US20220064691A1 (en) Decorated inclusion body and uses thereof
Fairhead et al. SpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly
Nellis et al. Preclinical manufacture of an anti‐HER2 scFv‐PEG‐DSPE, liposome‐inserting conjugate. 1. Gram‐scale production and purification
CA2985985A1 (en) Specific modification of antibody by igg-binding peptide
CN108883170A (zh) 可程序化的通用细胞受体及其使用方法
US11136609B2 (en) Separating agent for human serum-derived IgG polyclonal antibodies, and method for separating human serum-derived IgG polyclonal antibodies using same
Kalousková et al. Tumor marker b7-h6 bound to the coiled coil peptide-polymer conjugate enables targeted therapy by activating human natural killer cells
Pasupuleti et al. Genetic code expansion in E. coli enables production of a functional ‘ready-to-click’T cell receptor-specific scFv
US12234273B2 (en) Programmable immunocyte receptor complex system
Hansen et al. Polyclonal antibody production for membrane proteins via genetic immunization
CN109867725B (zh) PD-1-Fc融合蛋白及其制备方法和用途
JP2024505818A (ja) 細胞表面を修飾された赤血球及びその調製方法
Ye et al. High-level expression and characterization of an anti-VEGF165 single-chain variable fragment (scFv) by small ubiquitin-related modifier fusion in Escherichia coli
CN106536738B (zh) 抗体基因的表达-分泌系统
KR102309517B1 (ko) 표적 항원 발견, 표현형 선별 및 표적 세포 특이성 표적 에피토프를 규명하기 위한 그의 용도
JP6854342B2 (ja) ファージ表面上での二重特異性抗体の提示
KR20160103007A (ko) 재조합 편성 혐기성 그램 양성균
Wang et al. Recombinant human CD137L for cancer immunotherapy: effects of different fusions and linkers on its activity
CN112239504A (zh) 一种针对pd-l1的纳米抗体及其应用
CN106928355A (zh) 一种CD105纳米抗体Nb184
CN112210009A (zh) 一种针对pd1的单域抗体及其应用
Weyant et al. A modular platform for on-demand vaccine self-assembly enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens
US20260055207A1 (en) Heterodimeric protein production method, dimeric protein, monomeric protein, and target responsive heterodimeric protein screening method
Römer et al. Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted