AU2019360017B9 - Novel compounds - Google Patents
Novel compounds Download PDFInfo
- Publication number
- AU2019360017B9 AU2019360017B9 AU2019360017A AU2019360017A AU2019360017B9 AU 2019360017 B9 AU2019360017 B9 AU 2019360017B9 AU 2019360017 A AU2019360017 A AU 2019360017A AU 2019360017 A AU2019360017 A AU 2019360017A AU 2019360017 B9 AU2019360017 B9 AU 2019360017B9
- Authority
- AU
- Australia
- Prior art keywords
- benzofuran
- disorders
- formula
- pharmaceutically acceptable
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18200626 | 2018-10-16 | ||
| EP18200626.2 | 2018-10-16 | ||
| PCT/GB2019/052937 WO2020079422A1 (en) | 2018-10-16 | 2019-10-16 | Novel compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2019360017A1 AU2019360017A1 (en) | 2021-04-01 |
| AU2019360017B2 AU2019360017B2 (en) | 2025-03-06 |
| AU2019360017B9 true AU2019360017B9 (en) | 2025-03-27 |
Family
ID=63878368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019360017A Active AU2019360017B9 (en) | 2018-10-16 | 2019-10-16 | Novel compounds |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP3867247B1 (enExample) |
| JP (1) | JP7465868B2 (enExample) |
| KR (1) | KR102854594B1 (enExample) |
| AR (1) | AR116713A1 (enExample) |
| AU (1) | AU2019360017B9 (enExample) |
| BR (1) | BR112021006940A2 (enExample) |
| DK (1) | DK3867247T3 (enExample) |
| ES (1) | ES2988842T3 (enExample) |
| FI (1) | FI3867247T3 (enExample) |
| HR (1) | HRP20241318T1 (enExample) |
| HU (1) | HUE068686T2 (enExample) |
| IL (1) | IL282096B2 (enExample) |
| LT (1) | LT3867247T (enExample) |
| MX (1) | MX2021004386A (enExample) |
| PL (1) | PL3867247T3 (enExample) |
| PT (1) | PT3867247T (enExample) |
| SI (1) | SI3867247T1 (enExample) |
| TW (1) | TWI827706B (enExample) |
| WO (1) | WO2020079422A1 (enExample) |
| ZA (1) | ZA202101487B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12358901B2 (en) | 2018-10-16 | 2025-07-15 | Autifony Therapeutics Limited | KV3 modulators |
| JP7522203B2 (ja) * | 2020-02-06 | 2024-07-24 | アウトイフオンイ トヘラペウトイクス リミテッド | Ｋｖ３モジュレーター |
| CA3228446A1 (en) | 2021-08-09 | 2023-02-16 | Janssen Pharmaceutica Nv | Monoacylglycerol lipase modulators for use in autism spectrum disorders |
| US20240327406A1 (en) | 2021-08-10 | 2024-10-03 | Autifony Therapeutics Limited | Potassium channel modulators |
| EP4630117A1 (en) | 2022-12-06 | 2025-10-15 | Autifony Therapeutics Limited | Compounds for the treatment of centra nervous system disorders |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012076877A1 (en) * | 2010-12-06 | 2012-06-14 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5788404B2 (ja) | 2009-12-11 | 2015-09-30 | アウトイフオンイ トヘラペウトイクス リミテッド | イミダゾリジンジオン誘導体 |
| US9193704B2 (en) | 2011-06-07 | 2015-11-24 | Autifony Therapeutics Limited | Hydantoin derivatives as KV3 inhibitors |
| GB201209986D0 (en) | 2012-06-06 | 2012-07-18 | Autifony Therapeutics Ltd | Novel compounds |
| AU2012349847B2 (en) | 2011-12-06 | 2017-02-16 | Autifony Therapeutics Limited | Hydantoin derivatives useful as Kv3 inhibitors |
| EP2852588B8 (en) | 2012-05-22 | 2018-01-10 | Autifony Therapeutics Limited | Hydantoin derivatives as kv3 inhibitors |
| US9422252B2 (en) | 2012-05-22 | 2016-08-23 | Autifony Therapeutics Limited | Triazoles as Kv3 inhibitors |
| WO2013182851A1 (en) | 2012-06-06 | 2013-12-12 | Autifony Therapeutics Limited | Prophylaxis or treatment of diseases where a modulator of kv3.3 channels is required |
| GB201521751D0 (en) | 2015-12-10 | 2016-01-27 | Autifony Therapeutics Ltd | Novel uses |
| GB201522179D0 (en) | 2015-12-16 | 2016-01-27 | Autifony Therapeutics Ltd | Novel compounds |
| GB201613163D0 (en) | 2016-07-29 | 2016-09-14 | Autifony Therapeutics Ltd | Novel compounds |
| WO2018109484A1 (en) | 2016-12-16 | 2018-06-21 | Autifony Therapeutics Limited | Hydantoin modulators of kv3 channels |
-
2019
- 2019-10-16 TW TW108137290A patent/TWI827706B/zh active
- 2019-10-16 ES ES19790048T patent/ES2988842T3/es active Active
- 2019-10-16 HR HRP20241318TT patent/HRP20241318T1/hr unknown
- 2019-10-16 BR BR112021006940-2A patent/BR112021006940A2/pt unknown
- 2019-10-16 PL PL19790048.3T patent/PL3867247T3/pl unknown
- 2019-10-16 PT PT197900483T patent/PT3867247T/pt unknown
- 2019-10-16 IL IL282096A patent/IL282096B2/en unknown
- 2019-10-16 WO PCT/GB2019/052937 patent/WO2020079422A1/en not_active Ceased
- 2019-10-16 HU HUE19790048A patent/HUE068686T2/hu unknown
- 2019-10-16 DK DK19790048.3T patent/DK3867247T3/da active
- 2019-10-16 SI SI201930828T patent/SI3867247T1/sl unknown
- 2019-10-16 MX MX2021004386A patent/MX2021004386A/es unknown
- 2019-10-16 FI FIEP19790048.3T patent/FI3867247T3/fi active
- 2019-10-16 KR KR1020217014348A patent/KR102854594B1/ko active Active
- 2019-10-16 EP EP19790048.3A patent/EP3867247B1/en active Active
- 2019-10-16 AR ARP190102939A patent/AR116713A1/es unknown
- 2019-10-16 JP JP2021521058A patent/JP7465868B2/ja active Active
- 2019-10-16 LT LTEPPCT/GB2019/052937T patent/LT3867247T/lt unknown
- 2019-10-16 AU AU2019360017A patent/AU2019360017B9/en active Active
-
2021
- 2021-03-04 ZA ZA2021/01487A patent/ZA202101487B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012076877A1 (en) * | 2010-12-06 | 2012-06-14 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| DK3867247T3 (da) | 2024-09-16 |
| AU2019360017A1 (en) | 2021-04-01 |
| ZA202101487B (en) | 2024-05-30 |
| PT3867247T (pt) | 2024-09-17 |
| AR116713A1 (es) | 2021-06-02 |
| JP7465868B2 (ja) | 2024-04-11 |
| KR20210076081A (ko) | 2021-06-23 |
| EP3867247B1 (en) | 2024-07-24 |
| FI3867247T3 (fi) | 2024-10-30 |
| IL282096B2 (en) | 2024-07-01 |
| TW202035394A (zh) | 2020-10-01 |
| HRP20241318T1 (hr) | 2024-12-20 |
| IL282096A (en) | 2021-05-31 |
| PL3867247T3 (pl) | 2024-12-09 |
| JP2022505143A (ja) | 2022-01-14 |
| IL282096B1 (en) | 2024-03-01 |
| HUE068686T2 (hu) | 2025-01-28 |
| AU2019360017B2 (en) | 2025-03-06 |
| EP3867247A1 (en) | 2021-08-25 |
| SI3867247T1 (sl) | 2024-11-29 |
| TWI827706B (zh) | 2024-01-01 |
| MX2021004386A (es) | 2021-06-04 |
| BR112021006940A2 (pt) | 2021-07-13 |
| ES2988842T3 (es) | 2024-11-21 |
| KR102854594B1 (ko) | 2025-09-02 |
| WO2020079422A1 (en) | 2020-04-23 |
| LT3867247T (lt) | 2024-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SREP | Specification republished | ||
| FGA | Letters patent sealed or granted (standard patent) |