AU2019218989B2 - Chimeric antigen receptors targeting the tumor microenvironment - Google Patents

Chimeric antigen receptors targeting the tumor microenvironment

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Publication number
AU2019218989B2
AU2019218989B2 AU2019218989A AU2019218989A AU2019218989B2 AU 2019218989 B2 AU2019218989 B2 AU 2019218989B2 AU 2019218989 A AU2019218989 A AU 2019218989A AU 2019218989 A AU2019218989 A AU 2019218989A AU 2019218989 B2 AU2019218989 B2 AU 2019218989B2
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bite
car
egfr
antigen
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AU2019218989A1 (en
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Bryan CHOI
Marcela V. Maus
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General Hospital Corp
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General Hospital Corp
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Priority claimed from PCT/US2018/027783 external-priority patent/WO2018191748A1/en
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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AU2019218989A 2018-02-12 2019-02-12 Chimeric antigen receptors targeting the tumor microenvironment Active AU2019218989B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2026204039A AU2026204039A1 (en) 2018-02-12 2026-05-26 Chimeric antigen receptors targeting the tumor microenvironment

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862629593P 2018-02-12 2018-02-12
US62/629,593 2018-02-12
US201862658307P 2018-04-16 2018-04-16
AUPCT/US2018/027783 2018-04-16
PCT/US2018/027783 WO2018191748A1 (en) 2017-04-14 2018-04-16 Chimeric antigen receptor t cells targeting the tumor microenvironment
US62/658,307 2018-04-16
US201862746895P 2018-10-17 2018-10-17
US62/746,895 2018-10-17
PCT/US2019/017727 WO2019157533A1 (en) 2018-02-12 2019-02-12 Chimeric antigen receptors targeting the tumor microenvironment

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AU2019218989A1 AU2019218989A1 (en) 2020-08-27
AU2019218989B2 true AU2019218989B2 (en) 2026-02-26

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US (1) US20210038646A1 (enExample)
EP (1) EP3752170A4 (enExample)
JP (2) JP2021512635A (enExample)
CN (1) CN111971053A (enExample)
AU (2) AU2019218989B2 (enExample)
CA (1) CA3090546A1 (enExample)
ES (1) ES3068176T3 (enExample)
WO (1) WO2019157533A1 (enExample)

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