AU2018361867B2 - Brartemicin analogues - Google Patents

Brartemicin analogues Download PDF

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Publication number
AU2018361867B2
AU2018361867B2 AU2018361867A AU2018361867A AU2018361867B2 AU 2018361867 B2 AU2018361867 B2 AU 2018361867B2 AU 2018361867 A AU2018361867 A AU 2018361867A AU 2018361867 A AU2018361867 A AU 2018361867A AU 2018361867 B2 AU2018361867 B2 AU 2018361867B2
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AU
Australia
Prior art keywords
mmol
compound
formula
alkyl
subject
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AU2018361867A
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AU2018361867A1 (en
Inventor
Amy Jane FOSTER
Bridget Louise STOCKER
Mattheus Simon Maria TIMMER
Sho Yamasaki
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Victoria Link Ltd
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Victoria Link Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018361867A 2017-11-02 2018-11-02 Brartemicin analogues Active AU2018361867B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ73694117 2017-11-02
NZ736941 2017-11-02
PCT/NZ2018/050156 WO2019088854A1 (en) 2017-11-02 2018-11-02 Brartemicin analogues

Publications (2)

Publication Number Publication Date
AU2018361867A1 AU2018361867A1 (en) 2020-06-11
AU2018361867B2 true AU2018361867B2 (en) 2023-08-10

Family

ID=66332235

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018361867A Active AU2018361867B2 (en) 2017-11-02 2018-11-02 Brartemicin analogues

Country Status (5)

Country Link
US (2) US11510980B2 (https=)
EP (1) EP3710462A4 (https=)
JP (1) JP7360385B2 (https=)
AU (1) AU2018361867B2 (https=)
WO (1) WO2019088854A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018361867B2 (en) * 2017-11-02 2023-08-10 Victoria Link Ltd Brartemicin analogues
CA3091352A1 (en) * 2018-02-21 2019-08-29 The University Of Montana Diaryl trehalose compounds and uses thereof
JPWO2023277051A1 (https=) * 2021-06-30 2023-01-05
IL314325A (en) * 2022-01-27 2024-09-01 Citrachem Corp Methods of synthesizing cannabidiol, derivatives thereof, and other phytocannabinoids
CN114796247B (zh) * 2022-05-24 2023-08-08 广东医科大学 亚麻木酚素在制备抗轮状病毒药物的应用
JPWO2024219501A1 (https=) * 2023-04-20 2024-10-24
JP7632857B1 (ja) 2024-07-25 2025-02-19 博 村上 水溶性ｘ線造影剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307229A (en) * 1979-11-07 1981-12-22 Avraham Liav 6,6'-Diesters of trehalose and process for the synthesis thereof
WO2010050178A1 (ja) 2008-10-31 2010-05-06 大塚化学株式会社 トレハロース化合物、その製造方法、及び該化合物を含有する医薬
CN101914118B (zh) 2010-08-06 2012-07-04 山东大学 海藻糖衍生物及其制备方法与应用
CN102260297B (zh) * 2011-06-07 2013-11-13 山东大学 海藻糖酰胺衍生物及其制备方法与应用
AU2018361867B2 (en) * 2017-11-02 2023-08-10 Victoria Link Ltd Brartemicin analogues
CA3091352A1 (en) * 2018-02-21 2019-08-29 The University Of Montana Diaryl trehalose compounds and uses thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LIAV, A. ; DAS, B.C. ; GOREN, M.B.: "Diamide pseudo cord-factors: bis-N-acyl derivatives of 6,6'-diamino-6,6'-dideoxy-@a,@a-trehalose", CARBOHYDRATE RESEARCH, PERGAMON, GB, vol. 94, no. 2, 1 August 1981 (1981-08-01), GB , pages 230 - 235, XP026610288, ISSN: 0008-6215, DOI: 10.1016/S0008-6215(00)80721-1 *
LIAV, AVRAHAM ET AL.: "Synthesis of 6,6'-di-O-acylated alpha,alpha-trehaloses via 2,3,4,2',3',4'- hexa-O-benzyl-a,a-trehalose", CARBOHYDRATE RESEARCH, vol. 81, no. 1, 1 May 1980 (1980-05-01), pages C1 - C3 *

Also Published As

Publication number Publication date
EP3710462A4 (en) 2021-08-25
EP3710462A1 (en) 2020-09-23
WO2019088854A1 (en) 2019-05-09
JP2021501791A (ja) 2021-01-21
US20210177965A1 (en) 2021-06-17
AU2018361867A1 (en) 2020-06-11
US11510980B2 (en) 2022-11-29
JP7360385B2 (ja) 2023-10-12
US20230139366A1 (en) 2023-05-04

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Owner name: VICTORIA LINK LTD

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