AU2018307742A1 - Optical rejection photonic structures - Google Patents

Optical rejection photonic structures Download PDF

Info

Publication number
AU2018307742A1
AU2018307742A1 AU2018307742A AU2018307742A AU2018307742A1 AU 2018307742 A1 AU2018307742 A1 AU 2018307742A1 AU 2018307742 A AU2018307742 A AU 2018307742A AU 2018307742 A AU2018307742 A AU 2018307742A AU 2018307742 A1 AU2018307742 A1 AU 2018307742A1
Authority
AU
Australia
Prior art keywords
integrated device
excitation light
light
photodetector
spatial filter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2018307742A
Other languages
English (en)
Inventor
James Beach
Keith G. Fife
Farshid GHASEMI
Alexander Gondarenko
Jack Jewell
Ali KABIRI
Jeremy Lackey
Kyle Preston
Jonathan M. Rothberg
Gerard Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quantum Si Inc
Original Assignee
Quantum Si Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Si Inc filed Critical Quantum Si Inc
Publication of AU2018307742A1 publication Critical patent/AU2018307742A1/en
Priority to AU2024202571A priority Critical patent/AU2024202571A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/122—Basic optical elements, e.g. light-guiding paths
    • G02B6/1225—Basic optical elements, e.g. light-guiding paths comprising photonic band-gap structures or photonic lattices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/20—Filters
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/30—Polarising elements
    • G02B5/3025—Polarisers, i.e. arrangements capable of producing a definite output polarisation state from an unpolarised input state
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02—Optical fibres with cladding with or without a coating
    • G02B6/02295—Microstructured optical fibre
    • G02B6/02314—Plurality of longitudinal structures extending along optical fibre axis, e.g. holes
    • G02B6/02319—Plurality of longitudinal structures extending along optical fibre axis, e.g. holes characterised by core or core-cladding interface features
    • G02B6/02323—Core having lower refractive index than cladding, e.g. photonic band gap guiding
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
    • H10F39/00—Integrated devices, or assemblies of multiple devices, comprising at least one element covered by group H10F30/00, e.g. radiation detectors comprising photodiode arrays
    • H10F39/10—Integrated devices
    • H10F39/103—Integrated devices the at least one element covered by H10F30/00 having potential barriers, e.g. integrated devices comprising photodiodes or phototransistors
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10W—GENERIC PACKAGES, INTERCONNECTIONS, CONNECTORS OR OTHER CONSTRUCTIONAL DETAILS OF DEVICES COVERED BY CLASS H10
    • H10W90/00—Package configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/064—Stray light conditioning

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Glass Compositions (AREA)
  • Optical Measuring Cells (AREA)
AU2018307742A 2017-07-24 2018-07-23 Optical rejection photonic structures Abandoned AU2018307742A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024202571A AU2024202571A1 (en) 2017-07-24 2024-04-18 Optical rejection photonic structures

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762536268P 2017-07-24 2017-07-24
US62/536,268 2017-07-24
PCT/US2018/043333 WO2019023146A1 (en) 2017-07-24 2018-07-23 PHOTONIC STRUCTURES WITH OPTICAL RELEASE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024202571A Division AU2024202571A1 (en) 2017-07-24 2024-04-18 Optical rejection photonic structures

Publications (1)

Publication Number Publication Date
AU2018307742A1 true AU2018307742A1 (en) 2020-01-30

Family

ID=65019069

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018307742A Abandoned AU2018307742A1 (en) 2017-07-24 2018-07-23 Optical rejection photonic structures
AU2024202571A Abandoned AU2024202571A1 (en) 2017-07-24 2024-04-18 Optical rejection photonic structures

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024202571A Abandoned AU2024202571A1 (en) 2017-07-24 2024-04-18 Optical rejection photonic structures

Country Status (10)

Country Link
US (2) US11237326B2 (https=)
EP (1) EP3658900A4 (https=)
JP (1) JP7212030B2 (https=)
KR (1) KR102786367B1 (https=)
CN (1) CN111133294B (https=)
AU (2) AU2018307742A1 (https=)
BR (1) BR112020000799A2 (https=)
CA (1) CA3069974A1 (https=)
TW (1) TWI791567B (https=)
WO (1) WO2019023146A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123922A1 (en) 2013-02-05 2014-08-14 Butterfly Network, Inc. Cmos ultrasonic transducers and related apparatus and methods
CN105307559B (zh) * 2013-06-06 2020-06-05 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
US9067779B1 (en) 2014-07-14 2015-06-30 Butterfly Network, Inc. Microfabricated ultrasonic transducers and related apparatus and methods
EP3642611B1 (en) * 2017-06-21 2024-02-14 Butterfly Network, Inc. Microfabricated ultrasonic transducer having individual cells with electrically isolated electrode sections
BR112020000799A2 (pt) * 2017-07-24 2020-07-14 Quantum-Si Incorporated estruturas fotônicas de rejeição óptica
US10121811B1 (en) * 2017-08-25 2018-11-06 Taiwan Semiconductor Manufacturing Co., Ltd. Method of high-aspect ratio pattern formation with submicron pixel pitch
US11072827B2 (en) 2018-01-08 2021-07-27 Quantum-Si Incorporated System and methods for electrokinetic loading of sub-micron-scale reaction chambers
BR112021008098A2 (pt) 2018-11-15 2021-08-10 Quantum-Si Incorporated métodos e composições para o sequenciamento de proteínas
BR112021016310A2 (pt) * 2019-03-05 2021-10-13 Quantum-Si Incorporated Filtro de absorção óptico para dispositivo integrado
TWI705269B (zh) * 2019-03-27 2020-09-21 群光電子股份有限公司 影像擷取裝置、濾光膜及濾光膜的製作方法
EP3973272A1 (en) * 2019-06-28 2022-03-30 Quantum-Si Incorporated Optical and electrical secondary path rejection
CN114041074B (zh) * 2019-07-02 2024-08-20 3M创新有限公司 包括具有降频转换器的波长选择性光学滤光器的光学装置
EP4017363A4 (en) * 2019-08-20 2023-08-02 Profusa, Inc. OPTICAL FILTER DEVICE, SYSTEM AND METHOD FOR IMPROVED OPTICAL REJECTION OF OUT-OF-BAND WAVELENGTHS
US11630062B2 (en) * 2019-10-10 2023-04-18 Visera Technologies Company Limited Biosensor and method of forming the same
US11705472B2 (en) 2019-10-10 2023-07-18 Visera Technologies Company Limited Biosensor and method of distinguishing a light
AU2020372908A1 (en) 2019-10-29 2022-06-02 Quantum-Si Incorporated Peristaltic pumping of fluids and associated methods, systems, and devices
CA3159371A1 (en) 2019-10-31 2021-05-06 Quantum-Si Incorporated Pixel with enhanced drain
TW202145595A (zh) 2020-01-14 2021-12-01 美商寬騰矽公司 用於壽命及光譜特性分析之感應器
JP7763763B2 (ja) * 2020-01-14 2025-11-04 クアンタム－エスアイ インコーポレイテッド 寿命特性評価のための集積センサ
AU2021207899A1 (en) 2020-01-14 2022-09-08 Quantum-Si Incorporated Waveguide excitation uniformity
TW202147591A (zh) 2020-03-02 2021-12-16 美商寬騰矽公司 用於多維信號分析之整合感應器
EP4133524A2 (en) 2020-04-08 2023-02-15 Quantum-si Incorporated Integrated sensor with reduced skew
WO2021236983A2 (en) 2020-05-20 2021-11-25 Quantum-Si Incorporated Methods and compositions for protein sequencing
WO2022087240A2 (en) 2020-10-22 2022-04-28 Quantum-Si Incorporated Integrated circuit with sequentially-coupled charge storage and associated techniques
CN116710752A (zh) * 2020-10-27 2023-09-05 宽腾矽公司 利用光漂白信息的单个分子检测系统
US12297496B2 (en) * 2020-12-11 2025-05-13 Quantum-Si Incorporated Integrated circuit with improved charge transfer efficiency and associated techniques
JP2023554368A (ja) 2020-12-15 2023-12-27 クアンタム－エスアイ インコーポレイテッド 単一分子速度論による分子バーコード分析
CN118216003A (zh) * 2021-10-22 2024-06-18 伊鲁米纳公司 半导体光感测
WO2023137051A2 (en) * 2022-01-12 2023-07-20 Quantum-Si Incorporated Integrated sensor
CN114689510B (zh) * 2022-03-15 2025-08-05 南京大学 一种片上荧光激发与采集系统
US12504376B2 (en) * 2022-03-17 2025-12-23 Visera Technologies Company Limited Bio-detection device, bio-detection system, and bio-detection method
US20240165611A1 (en) * 2022-11-22 2024-05-23 Visera Technologies Company Limited Biosensor and cell manipulation method
WO2025191014A1 (en) 2024-03-12 2025-09-18 Sparrow Quantum Aps A method of calibrating a photon source system

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547849A (en) * 1993-02-17 1996-08-20 Biometric Imaging, Inc. Apparatus and method for volumetric capillary cytometry
US5500540A (en) * 1994-04-15 1996-03-19 Photonics Research Incorporated Wafer scale optoelectronic package
US5814565A (en) 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5835646A (en) * 1995-09-19 1998-11-10 Fujitsu Limited Active optical circuit sheet or active optical circuit board, active optical connector and optical MCM, process for fabricating optical waveguide, and devices obtained thereby
US6825921B1 (en) 1999-11-10 2004-11-30 Molecular Devices Corporation Multi-mode light detection system
GB9810350D0 (en) * 1998-05-14 1998-07-15 Ciba Geigy Ag Organic compounds
US6787308B2 (en) * 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
JP3891737B2 (ja) * 1999-04-19 2007-03-14 シャープ株式会社 発振器及びその発振特性調整方法
US7175811B2 (en) * 2000-04-28 2007-02-13 Edgelight Biosciences Micro-array evanescent wave fluorescence detection device
US6917726B2 (en) * 2001-09-27 2005-07-12 Cornell Research Foundation, Inc. Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes
AU2001264603A1 (en) * 2000-05-17 2001-11-26 Quantum Vision, Inc. Waveguide based light source
FR2813121A1 (fr) 2000-08-21 2002-02-22 Claude Weisbuch Dispositif perfectionne de support d'elements chromophores
DE10145701A1 (de) * 2001-09-17 2003-04-10 Infineon Technologies Ag Fluoreszenz-Biosensorchip und Fluoreszenz-Biosensorchip-Anordnung
US6600847B2 (en) * 2001-11-05 2003-07-29 Quantum Photonics, Inc Semiconductor optical device with improved efficiency and output beam characteristics
US6906784B2 (en) * 2002-03-04 2005-06-14 Zygo Corporation Spatial filtering in interferometry
US6867420B2 (en) * 2002-06-03 2005-03-15 The Regents Of The University Of California Solid-state detector and optical system for microchip analyzers
JP3801550B2 (ja) * 2002-09-12 2006-07-26 ユーディナデバイス株式会社 光変調器及びその製造方法
FR2846745B1 (fr) * 2002-10-30 2004-12-24 Genewave Dispositif de support d'elements chromophores.
US7057135B2 (en) * 2004-03-04 2006-06-06 Matsushita Electric Industrial, Co. Ltd. Method of precise laser nanomachining with UV ultrafast laser pulses
US7511247B2 (en) * 2004-03-22 2009-03-31 Panasonic Corporation Method of controlling hole shape during ultrafast laser machining by manipulating beam polarization
US7342641B2 (en) * 2005-02-22 2008-03-11 Nikon Corporation Autofocus methods and devices for lithography
US7738086B2 (en) * 2005-05-09 2010-06-15 The Trustees Of Columbia University In The City Of New York Active CMOS biosensor chip for fluorescent-based detection
US7265840B2 (en) * 2005-06-16 2007-09-04 Matsushita Electric Industrial Co., Ltd. Coupling method for coupling high power optical beams into an optical waveguide
US7426322B2 (en) * 2005-07-20 2008-09-16 Searete Llc. Plasmon photocatalysis
JP5022221B2 (ja) * 2005-09-06 2012-09-12 株式会社 東北テクノアーチ 波長分割画像計測装置
US7692783B2 (en) * 2006-02-13 2010-04-06 Pacific Biosciences Of California Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
US8975216B2 (en) * 2006-03-30 2015-03-10 Pacific Biosciences Of California Articles having localized molecules disposed thereon and methods of producing same
US7709808B2 (en) * 2006-05-16 2010-05-04 Applied Biosystems, Llc Systems, methods and apparatus for single molecule sequencing
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
US8207509B2 (en) * 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
EP3936857B1 (en) * 2006-09-01 2023-06-21 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
FR2908888B1 (fr) * 2006-11-21 2012-08-03 Centre Nat Rech Scient Dispositif pour la detection exaltee de l'emission d'une particule cible
WO2009005748A1 (en) * 2007-06-29 2009-01-08 The Trustees Of Columbia University In The City Ofnew York Optical imaging or spectroscopy systems and methods
US8885987B2 (en) * 2007-09-06 2014-11-11 Quantum Semiconductor Llc Photonic via waveguide for pixel arrays
WO2009082706A1 (en) * 2007-12-21 2009-07-02 The Trustees Of Columbia University In The City Of New York Active cmos sensor array for electrochemical biomolecular detection
WO2009107041A1 (en) * 2008-02-25 2009-09-03 Koninklijke Philips Electronics N.V. Optical sensor for measuring emission light from an analyte
JP5254323B2 (ja) * 2008-05-10 2013-08-07 株式会社フォトニックラティス 光学歪み計測装置
CA2737505C (en) * 2008-09-16 2017-08-29 Pacific Biosciences Of California, Inc. Substrates and optical systems and methods of use thereof
US8278728B2 (en) * 2009-10-17 2012-10-02 Florida Institute Of Technology Array of concentric CMOS photodiodes for detection and de-multiplexing of spatially modulated optical channels
US10568963B2 (en) * 2009-10-21 2020-02-25 Health Research, Inc. Multifunctional nanoplatforms for fluorescence imaging and photodynamic therapy developed by post-loading photosensitizer and fluorophore to polyacrylamide nanoparticles
CN102985803A (zh) * 2010-02-19 2013-03-20 加利福尼亚太平洋生物科学股份有限公司 集成的分析系统和方法
US8655138B2 (en) * 2010-05-10 2014-02-18 Cornell University Waveguide structure and related fabrication method
US8865078B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
GB2483482A (en) * 2010-09-09 2012-03-14 Univ Dublin City An optical testing system
CA2856163C (en) * 2011-10-28 2019-05-07 Illumina, Inc. Microarray fabrication system and method
US9606060B2 (en) * 2012-01-13 2017-03-28 California Institute Of Technology Filterless time-domain detection of one or more fluorophores
JP2013160623A (ja) * 2012-02-03 2013-08-19 Tokyo Institute Of Technology 光測定装置
WO2013173698A1 (en) * 2012-05-18 2013-11-21 The Trustees Of Columbia University In The City Of New York System, method and computer-accessible medium for providing fluorescence attenuation
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
EP3699577B1 (en) 2012-08-20 2023-11-08 Illumina, Inc. System for fluorescence lifetime based sequencing
US20140145647A1 (en) * 2012-11-26 2014-05-29 Quantum Electro Opto Systems Sdn. Bhd. Optical Tilted Charge Devices And Techniques
US9223084B2 (en) * 2012-12-18 2015-12-29 Pacific Biosciences Of California, Inc. Illumination of optical analytical devices
EP2989442A4 (en) * 2013-07-09 2016-12-28 Halliburton Energy Services Inc INTEGRATED COMPUTING ELEMENTS HAVING SELECTIVE FREQUENCY SURFACE
CN105917003A (zh) * 2013-11-17 2016-08-31 宽腾矽公司 用于生物和化学试样的快速分析的有源像素集成装置
CN107272199B (zh) * 2013-11-27 2023-04-07 奇跃公司 虚拟和增强现实系统与方法
US9528925B2 (en) * 2014-02-14 2016-12-27 Palo Alto Research Center Incorporated Spatial modulation of light to determine object position
US9765395B2 (en) 2014-04-28 2017-09-19 Nanomedical Diagnostics, Inc. System and method for DNA sequencing and blood chemistry analysis
EP3146312B1 (en) * 2014-05-22 2018-07-04 IMEC vzw Integrated semiconductor device for detecting fluorescent particles
MX384725B (es) * 2014-08-08 2025-03-14 Quantum Si Inc Dispositivo integrado con fuente de luz externa para el sondeo, detección y análisis de moléculas.
CN106796175B (zh) * 2014-08-08 2021-01-05 宽腾矽公司 用于探测、检测和分析分子的光学系统和检测芯片
KR102585730B1 (ko) * 2014-08-08 2023-10-10 퀀텀-에스아이 인코포레이티드 수신된 광자들의 시간 비닝을 위한 집적 디바이스
EP3186617A4 (en) * 2014-08-27 2018-04-25 Pacific Biosciences Of California, Inc. Arrays of integrated analytcal devices
US9666748B2 (en) * 2015-01-14 2017-05-30 International Business Machines Corporation Integrated on chip detector and zero waveguide module structure for use in DNA sequencing
EP3271762B1 (en) * 2015-03-16 2023-01-04 Pacific Biosciences of California, Inc. Analytical system comprising integrated devices and systems for free-space optical coupling
US10119915B2 (en) * 2015-04-09 2018-11-06 Visera Technologies Company Limited Detection device for specimens
CA2986237A1 (en) * 2015-05-20 2016-11-24 Quantum-Si Incorporated Method of determining the sequence of a nucleic acid using time resolved luminescence
JP6743410B2 (ja) * 2016-02-24 2020-08-19 セイコーエプソン株式会社 量子干渉装置、原子発振器および電子機器
WO2018013243A1 (en) 2016-06-01 2018-01-18 Quantum-Si Incorporated Integrated device for detecting and analyzing molecules
BR112020000799A2 (pt) * 2017-07-24 2020-07-14 Quantum-Si Incorporated estruturas fotônicas de rejeição óptica
US10371906B1 (en) * 2018-01-17 2019-08-06 The United States Of America As Represented By The Secretary Of The Army Method and apparatus for delivering the fiber laser radiation into dynamical waveguide
MX2021008133A (es) * 2019-01-03 2021-08-11 Quantum Si Inc Guias de ondas opticas y acopladores para suministrar luz a un conjunto de elementos fotonicos.
EP3973272A1 (en) * 2019-06-28 2022-03-30 Quantum-Si Incorporated Optical and electrical secondary path rejection
AU2021207899A1 (en) * 2020-01-14 2022-09-08 Quantum-Si Incorporated Waveguide excitation uniformity
IL294730A (en) * 2020-01-14 2022-09-01 Quantum Si Inc A pulsed laser light source for producing excitation light in an integrated system
TW202145595A (zh) * 2020-01-14 2021-12-01 美商寬騰矽公司 用於壽命及光譜特性分析之感應器
TW202147591A (zh) * 2020-03-02 2021-12-16 美商寬騰矽公司 用於多維信號分析之整合感應器
EP4133524A2 (en) * 2020-04-08 2023-02-15 Quantum-si Incorporated Integrated sensor with reduced skew
WO2022087240A2 (en) * 2020-10-22 2022-04-28 Quantum-Si Incorporated Integrated circuit with sequentially-coupled charge storage and associated techniques
EP4217715A1 (en) * 2020-10-23 2023-08-02 Quantum-si Incorporated Systems and methods for sample process scaling
JP2023550693A (ja) * 2020-10-27 2023-12-05 クアンタム－エスアイ インコーポレイテッド 光退色情報を使用する単一分子検出システム
EP4217716A4 (en) * 2020-10-27 2024-11-27 Quantum-si Incorporated CALIBRATION OF SINGLE MOLECULE DETECTION SYSTEM
WO2022132821A1 (en) * 2020-12-15 2022-06-23 Quantum-Si Incorporated Systems and methods for chip regeneration
IL307484A (en) * 2021-04-08 2023-12-01 Quantum Si Inc Integrated circuit having mirrored pixel configuration
WO2023114209A1 (en) * 2021-12-14 2023-06-22 Quantum-Si Incorporated Methods for loading and data acquisition
WO2023137051A2 (en) * 2022-01-12 2023-07-20 Quantum-Si Incorporated Integrated sensor
WO2023137056A2 (en) * 2022-01-12 2023-07-20 Quantum-Si Incorporated Techniques for sequencing

Also Published As

Publication number Publication date
BR112020000799A2 (pt) 2020-07-14
KR102786367B1 (ko) 2025-03-26
US20220113469A1 (en) 2022-04-14
WO2019023146A1 (en) 2019-01-31
JP7212030B2 (ja) 2023-01-24
US20190025511A1 (en) 2019-01-24
CA3069974A1 (en) 2019-01-31
US11237326B2 (en) 2022-02-01
JP2020529005A (ja) 2020-10-01
KR20200028474A (ko) 2020-03-16
AU2024202571A1 (en) 2024-05-09
EP3658900A4 (en) 2021-04-07
TWI791567B (zh) 2023-02-11
TW201920941A (zh) 2019-06-01
CN111133294B (zh) 2024-05-24
CN111133294A (zh) 2020-05-08
EP3658900A1 (en) 2020-06-03

Similar Documents

Publication Publication Date Title
US11237326B2 (en) Optical rejection photonic structures using two spatial filters
AU2023200860B2 (en) Optical coupler and waveguide system
JP7746169B2 (ja) 光学的および電気的な二次経路の除去
CN114222911A (zh) 用于集成装置的光学奈米结构抑制器及其方法
JP2023510577A (ja) 寿命特性評価のための集積センサ
IL294733A (en) Uniformity of waveguide excitation
KR20220140523A (ko) 수명 플러스 스펙트럼 특성화를 위한 센서
CN116806307A (zh) 具有改进的电荷转移效率的集成电路及相关技术
WO2023137051A2 (en) Integrated sensor
US20220128456A1 (en) Systems and methods for sample process scaling

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted