AU2018280742B2 - Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis - Google Patents

Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis Download PDF

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Publication number
AU2018280742B2
AU2018280742B2 AU2018280742A AU2018280742A AU2018280742B2 AU 2018280742 B2 AU2018280742 B2 AU 2018280742B2 AU 2018280742 A AU2018280742 A AU 2018280742A AU 2018280742 A AU2018280742 A AU 2018280742A AU 2018280742 B2 AU2018280742 B2 AU 2018280742B2
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dose
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AU2018280742A1 (en
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Jean-Pierre Gotteland
Ernest Loumaye
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Kissei Pharmaceutical Co Ltd
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Kissei Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
AU2018280742A 2017-06-05 2018-06-05 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis Active AU2018280742B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024201701A AU2024201701B2 (en) 2017-06-05 2024-03-14 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762515268P 2017-06-05 2017-06-05
US62/515,268 2017-06-05
PCT/EP2018/064768 WO2018224498A1 (en) 2017-06-05 2018-06-05 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis

Related Child Applications (1)

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AU2024201701A Division AU2024201701B2 (en) 2017-06-05 2024-03-14 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis

Publications (2)

Publication Number Publication Date
AU2018280742A1 AU2018280742A1 (en) 2020-01-30
AU2018280742B2 true AU2018280742B2 (en) 2023-12-21

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AU2018280742A Active AU2018280742B2 (en) 2017-06-05 2018-06-05 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis
AU2024201701A Active AU2024201701B2 (en) 2017-06-05 2024-03-14 Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis

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Country Status (12)

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US (2) US11980621B2 (https=)
EP (1) EP3634418A1 (https=)
JP (2) JP7348171B2 (https=)
KR (2) KR20250117836A (https=)
CN (1) CN110996956A (https=)
AU (2) AU2018280742B2 (https=)
CA (1) CA3066190A1 (https=)
EA (1) EA201992612A1 (https=)
MA (1) MA49256A (https=)
MX (1) MX2019014483A (https=)
SG (1) SG11201911598WA (https=)
WO (1) WO2018224498A1 (https=)

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ES2912929T5 (en) 2016-09-30 2025-05-09 Sumitomo Pharma Switzerland Gmbh Methods of treating uterine fibroids and endometriosis
KR102884301B1 (ko) 2017-06-05 2025-11-11 깃세이 야쿠힌 고교 가부시키가이샤 자궁 근종을 치료하고 월경혈량을 감소시키기 위한 고나도트로핀 방출 호르몬 길항제 투약 요법
EA201992612A1 (ru) 2017-06-05 2020-05-20 Обсева С.А. Схемы применения антагониста гонадотропин-высвобождающего гормона для лечения эндометриоза
CA3117092A1 (en) 2018-10-29 2020-05-07 ObsEva S.A. Compositions and methods for the treatment of adenomyosis and rectovaginal endometriosis
CN114466665A (zh) * 2019-08-08 2022-05-10 奥布赛瓦股份公司 用于治疗雌激素依赖性病症的组合物和方法
CN113384581B (zh) * 2020-03-12 2023-11-14 成都倍特药业股份有限公司 一种包含促性腺激素释放激素拮抗剂的药物组合物
CA3185151A1 (en) 2020-05-29 2021-12-02 Myovant Sciences Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
WO2022101303A1 (en) * 2020-11-11 2022-05-19 Myovant Sciences Gmbh Methods of administering relugolix
CN116940575A (zh) * 2021-02-23 2023-10-24 深圳市康哲药业有限公司 噻吩并嘧啶二酮类化合物及其应用
CN115232144B (zh) * 2021-04-22 2024-04-02 长春金赛药业有限责任公司 含氮稠环类衍生物、药物组合物及其制备方法和应用

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KR102884301B1 (ko) 2017-06-05 2025-11-11 깃세이 야쿠힌 고교 가부시키가이샤 자궁 근종을 치료하고 월경혈량을 감소시키기 위한 고나도트로핀 방출 호르몬 길항제 투약 요법
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Also Published As

Publication number Publication date
WO2018224498A1 (en) 2018-12-13
JP2020522571A (ja) 2020-07-30
CN110996956A (zh) 2020-04-10
AU2024201701A1 (en) 2024-04-04
US20200138819A1 (en) 2020-05-07
JP7348171B2 (ja) 2023-09-20
US11980621B2 (en) 2024-05-14
KR102839190B1 (ko) 2025-07-28
CA3066190A1 (en) 2018-12-13
JP7657855B2 (ja) 2025-04-07
KR20250117836A (ko) 2025-08-05
SG11201911598WA (en) 2020-01-30
AU2018280742A1 (en) 2020-01-30
AU2024201701B2 (en) 2025-04-10
JP2023113715A (ja) 2023-08-16
KR20200027481A (ko) 2020-03-12
EA201992612A1 (ru) 2020-05-20
MA49256A (fr) 2021-05-26
US20240293414A1 (en) 2024-09-05
EP3634418A1 (en) 2020-04-15
MX2019014483A (es) 2020-08-17

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: KISSEI PHARMACEUTICAL CO., LTD.

Free format text: FORMER APPLICANT(S): OBSEVA S.A.

FGA Letters patent sealed or granted (standard patent)