AU2018270396B2 - Treatment of multiple sclerosis with adipose-derived stem cells - Google Patents

Treatment of multiple sclerosis with adipose-derived stem cells Download PDF

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Publication number
AU2018270396B2
AU2018270396B2 AU2018270396A AU2018270396A AU2018270396B2 AU 2018270396 B2 AU2018270396 B2 AU 2018270396B2 AU 2018270396 A AU2018270396 A AU 2018270396A AU 2018270396 A AU2018270396 A AU 2018270396A AU 2018270396 B2 AU2018270396 B2 AU 2018270396B2
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hadscs
cells
batch
tissue
administration
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AU2018270396A1 (en
Inventor
Frida Grynspan
Ehud Marom
Dima YUDIN
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Stem Cell Medicine Ltd
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Stem Cell Medicine Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2018270396A 2017-05-15 2018-05-14 Treatment of multiple sclerosis with adipose-derived stem cells Active AU2018270396B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762506006P 2017-05-15 2017-05-15
US62/506,006 2017-05-15
PCT/IL2018/050523 WO2018211498A1 (en) 2017-05-15 2018-05-14 Treatment of multiple sclerosis with adipose-derived stem cells

Publications (2)

Publication Number Publication Date
AU2018270396A1 AU2018270396A1 (en) 2020-01-02
AU2018270396B2 true AU2018270396B2 (en) 2025-03-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018270396A Active AU2018270396B2 (en) 2017-05-15 2018-05-14 Treatment of multiple sclerosis with adipose-derived stem cells

Country Status (8)

Country Link
US (1) US11510946B2 (cg-RX-API-DMAC7.html)
EP (1) EP3624816A4 (cg-RX-API-DMAC7.html)
JP (1) JP2020519645A (cg-RX-API-DMAC7.html)
CN (1) CN110573170A (cg-RX-API-DMAC7.html)
AU (1) AU2018270396B2 (cg-RX-API-DMAC7.html)
CA (1) CA3062123A1 (cg-RX-API-DMAC7.html)
IL (1) IL269893B2 (cg-RX-API-DMAC7.html)
WO (1) WO2018211498A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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WO2018211498A1 (en) 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells
AU2017414803B2 (en) 2017-05-15 2025-02-13 Mapi Pharma Ltd. Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
IL272145A (en) 2020-01-20 2021-07-29 Stem Cell Medicine Ltd Cosmetic preparations with protein concentrate from a conditioned growth medium of stem cells from adipose tissue
CN115624571A (zh) * 2022-12-21 2023-01-20 北京瑷格干细胞科技有限公司 人脂肪间充质干细胞在制备治疗硬皮病药物中的应用
CN115624570A (zh) * 2022-12-21 2023-01-20 北京瑷格干细胞科技有限公司 人脂肪间充质干细胞在制备治疗结缔组织疾病药物中的应用

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Also Published As

Publication number Publication date
IL269893B1 (en) 2023-06-01
IL269893A (cg-RX-API-DMAC7.html) 2019-11-28
EP3624816A1 (en) 2020-03-25
US20200188439A1 (en) 2020-06-18
WO2018211498A1 (en) 2018-11-22
CA3062123A1 (en) 2018-11-22
JP2020519645A (ja) 2020-07-02
AU2018270396A1 (en) 2020-01-02
CN110573170A (zh) 2019-12-13
US11510946B2 (en) 2022-11-29
EP3624816A4 (en) 2021-02-24
IL269893B2 (en) 2023-10-01

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