AU2018255244A1 - Methods and antibodies for diabetes-related applications - Google Patents

Methods and antibodies for diabetes-related applications Download PDF

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Publication number
AU2018255244A1
AU2018255244A1 AU2018255244A AU2018255244A AU2018255244A1 AU 2018255244 A1 AU2018255244 A1 AU 2018255244A1 AU 2018255244 A AU2018255244 A AU 2018255244A AU 2018255244 A AU2018255244 A AU 2018255244A AU 2018255244 A1 AU2018255244 A1 AU 2018255244A1
Authority
AU
Australia
Prior art keywords
antibody
sample
gcd59
amino acid
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2018255244A
Other languages
English (en)
Inventor
Michael Chorev
Jose A. Halperin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mellitus LLC
Original Assignee
Mellitus LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mellitus LLC filed Critical Mellitus LLC
Publication of AU2018255244A1 publication Critical patent/AU2018255244A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2018255244A 2017-04-21 2018-04-17 Methods and antibodies for diabetes-related applications Abandoned AU2018255244A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762488346P 2017-04-21 2017-04-21
US62/488,346 2017-04-21
PCT/US2018/027856 WO2018195008A1 (en) 2017-04-21 2018-04-17 Methods and antibodies for diabetes-related applications

Publications (1)

Publication Number Publication Date
AU2018255244A1 true AU2018255244A1 (en) 2019-10-31

Family

ID=63856388

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018255244A Abandoned AU2018255244A1 (en) 2017-04-21 2018-04-17 Methods and antibodies for diabetes-related applications

Country Status (7)

Country Link
US (1) US11866506B2 (enExample)
EP (1) EP3612625A4 (enExample)
JP (2) JP7303182B2 (enExample)
AU (1) AU2018255244A1 (enExample)
SG (1) SG11201909708VA (enExample)
TW (1) TW201902927A (enExample)
WO (1) WO2018195008A1 (enExample)

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* Cited by examiner, † Cited by third party
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WO2018195008A1 (en) 2017-04-21 2018-10-25 Mellitus, Llc Methods and antibodies for diabetes-related applications
CN112924682B (zh) * 2019-12-05 2023-02-10 张曼 尿液纤维蛋白原α链蛋白及其多肽片段在正常妊娠中的应用
US11303968B1 (en) 2020-10-09 2022-04-12 Hulu, LLC Personalized ranking of entities in an electronic programming guide for live television
CN112904009B (zh) * 2021-02-19 2022-03-18 山东莱博生物科技有限公司 一种检测糖基化cd59的磁性微球检测试剂盒及其应用
WO2022241236A2 (en) * 2021-05-13 2022-11-17 Mellitus, Llc Methods and reagents for protein analysis
CN115290609B (zh) * 2021-12-22 2024-08-09 温州医科大学 快速检测肝素的试剂及检测方法
CN115144348B (zh) * 2022-07-06 2025-02-14 浙江伊利康生物技术有限公司 糖化白蛋白检测试剂盒、制备方法及其应用方法
US20260234637A1 (en) * 2023-02-12 2026-08-13 Cumbara Biotechnologies Ltd Targeted reduction of cd59 for use in treating disease
EP4725031A1 (en) * 2023-06-07 2026-04-15 Dexcom, Inc. Systems and methods for diabetes prediction
JP2025026011A (ja) 2023-08-10 2025-02-21 株式会社ツジデン 光集光補助フィルム、該光集光補助フィルムを搭載するエッジライト型バックライトユニット、及び該エッジライト型バックライトを搭載する液晶表示装置。
WO2026043816A1 (en) * 2024-08-23 2026-02-26 Preemier Llc Systems and methods for assessing glycated fetal hemoglobin

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Also Published As

Publication number Publication date
EP3612625A1 (en) 2020-02-26
JP2020517306A (ja) 2020-06-18
EP3612625A4 (en) 2021-08-18
WO2018195008A1 (en) 2018-10-25
JP2023078133A (ja) 2023-06-06
US20210284751A1 (en) 2021-09-16
SG11201909708VA (en) 2019-11-28
JP7303182B2 (ja) 2023-07-04
TW201902927A (zh) 2019-01-16
US11866506B2 (en) 2024-01-09

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application