AU2018215857A1 - Cancer therapeutic - Google Patents
Cancer therapeutic Download PDFInfo
- Publication number
- AU2018215857A1 AU2018215857A1 AU2018215857A AU2018215857A AU2018215857A1 AU 2018215857 A1 AU2018215857 A1 AU 2018215857A1 AU 2018215857 A AU2018215857 A AU 2018215857A AU 2018215857 A AU2018215857 A AU 2018215857A AU 2018215857 A1 AU2018215857 A1 AU 2018215857A1
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- Prior art keywords
- inhibitor
- inhibitors
- methyl
- hydroxy
- patient
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- 235000008209 xanthohumol Nutrition 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
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- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
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- BPKIMPVREBSLAJ-QTBYCLKRSA-N ziconotide Chemical compound C([C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]2C(=O)N[C@@H]3C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC2)C(N)=O)=O)CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC3)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N1)=O)CCSC)[C@@H](C)O)C1=CC=C(O)C=C1 BPKIMPVREBSLAJ-QTBYCLKRSA-N 0.000 description 1
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Classifications
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2024200098A AU2024200098A1 (en) | 2017-01-31 | 2024-01-07 | Cancer therapeutic |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201762452479P | 2017-01-31 | 2017-01-31 | |
| US62/452,479 | 2017-01-31 | ||
| PCT/NZ2018/050006 WO2018143826A1 (en) | 2017-01-31 | 2018-01-31 | Cancer therapeutic |
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| AU2024200098A Division AU2024200098A1 (en) | 2017-01-31 | 2024-01-07 | Cancer therapeutic |
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| JP (2) | JP2020515523A (enExample) |
| CN (1) | CN110494142A (enExample) |
| AU (2) | AU2018215857A1 (enExample) |
| CA (1) | CA3051840A1 (enExample) |
| WO (1) | WO2018143826A1 (enExample) |
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| WO2020027665A1 (en) * | 2018-07-30 | 2020-02-06 | Gillies Mcindoe Research Institute | Novel pharmaceutical compositions for cancer therapy |
| WO2020135920A1 (en) * | 2018-12-28 | 2020-07-02 | Université Libre de Bruxelles | Kit for inhaled chemotherapy, and treatment of lung cancer with said kit |
| CA3166161A1 (en) * | 2020-01-29 | 2021-08-05 | Paul Frank Davis | Methods and compositions for the treatment of hemangioma |
| WO2022187351A1 (en) * | 2021-03-03 | 2022-09-09 | Signpath Pharma, Inc | Treatment for malignant pleural effusion in humans |
| CN113069443A (zh) * | 2021-04-12 | 2021-07-06 | 四川大学 | 奈必洛尔在制备预防和/或治疗口腔白斑及口腔鳞状细胞癌的药物中的用途 |
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| US20070093457A1 (en) * | 2004-02-11 | 2007-04-26 | Nadir Arber | Compositions for treatment of cancer and inflammation with curcumin and at least one nsaid |
| WO2016004218A1 (en) * | 2014-07-01 | 2016-01-07 | Vicus Therapeutics, Llc | Combination drug therapies for cancer and methods of making and using them |
| MX2017001954A (es) * | 2014-08-12 | 2017-08-14 | Gillies Mcindoe Res Inst | Diagnostico y terapia del cancer. |
| WO2016054511A1 (en) * | 2014-10-02 | 2016-04-07 | The Board Of Regents Of The University Of Texas System | Use of mtor inhibitors for prevention of aging-associated dysfunction of stem cells |
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2018
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- 2018-01-31 EP EP18747771.6A patent/EP3576746A4/en not_active Withdrawn
- 2018-01-31 AU AU2018215857A patent/AU2018215857A1/en not_active Abandoned
- 2018-01-31 WO PCT/NZ2018/050006 patent/WO2018143826A1/en not_active Ceased
- 2018-01-31 CN CN201880019933.1A patent/CN110494142A/zh active Pending
- 2018-01-31 US US16/482,056 patent/US20200197335A1/en not_active Abandoned
- 2018-01-31 JP JP2019541267A patent/JP2020515523A/ja active Pending
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2024
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Also Published As
| Publication number | Publication date |
|---|---|
| US20200197335A1 (en) | 2020-06-25 |
| CA3051840A1 (en) | 2018-08-09 |
| CN110494142A (zh) | 2019-11-22 |
| EP3576746A1 (en) | 2019-12-11 |
| US20230364037A1 (en) | 2023-11-16 |
| EP3576746A4 (en) | 2020-09-09 |
| WO2018143826A1 (en) | 2018-08-09 |
| JP2023075272A (ja) | 2023-05-30 |
| AU2024200098A1 (en) | 2024-01-25 |
| JP2020515523A (ja) | 2020-05-28 |
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| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |