AU2017428907B2 - Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches - Google Patents

Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches Download PDF

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Publication number
AU2017428907B2
AU2017428907B2 AU2017428907A AU2017428907A AU2017428907B2 AU 2017428907 B2 AU2017428907 B2 AU 2017428907B2 AU 2017428907 A AU2017428907 A AU 2017428907A AU 2017428907 A AU2017428907 A AU 2017428907A AU 2017428907 B2 AU2017428907 B2 AU 2017428907B2
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AU
Australia
Prior art keywords
zolmitriptan
patch
coating
drug
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2017428907A
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English (en)
Other versions
AU2017428907A1 (en
Inventor
Mahmoud Ameri
Yi Ao
Donald Kellerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zosano Pharma Corp
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Zosano Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zosano Pharma Corp filed Critical Zosano Pharma Corp
Publication of AU2017428907A1 publication Critical patent/AU2017428907A1/en
Assigned to ZOSANO PHARMA CORPORATION reassignment ZOSANO PHARMA CORPORATION Request for Assignment Assignors: ZP OPCO, INC.
Application granted granted Critical
Publication of AU2017428907B2 publication Critical patent/AU2017428907B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AU2017428907A 2017-08-23 2017-08-23 Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches Expired - Fee Related AU2017428907B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2017/048258 WO2019040063A1 (en) 2017-08-23 2017-08-23 METHOD FOR QUICKLY PREPARING THERAPEUTIC CONCENTRATIONS OF ZOLMITRIPTAN FOR THE TREATMENT OF HORTON MIGRAINS AND HEADPHONES

Publications (2)

Publication Number Publication Date
AU2017428907A1 AU2017428907A1 (en) 2020-03-05
AU2017428907B2 true AU2017428907B2 (en) 2021-12-16

Family

ID=59829462

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017428907A Expired - Fee Related AU2017428907B2 (en) 2017-08-23 2017-08-23 Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches

Country Status (8)

Country Link
EP (1) EP3672570A1 (ko)
JP (2) JP7219384B2 (ko)
KR (2) KR102340393B1 (ko)
CN (1) CN111050749A (ko)
AU (1) AU2017428907B2 (ko)
CA (2) CA3073442C (ko)
IL (1) IL272776B2 (ko)
WO (1) WO2019040063A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017143345A1 (en) 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2020245667A1 (en) * 2019-06-06 2020-12-10 Kindeva Drug Delivery L.P. Microarray carrier for microarray applicator
US11638809B2 (en) * 2019-06-28 2023-05-02 Passport Technologies, Inc. Triptan microporation delivery system
CN114699510A (zh) * 2021-12-29 2022-07-05 浙江湃肽生物有限公司 一种司美格鲁肽微针阵列及其制备方法
CN115887903A (zh) * 2022-12-15 2023-04-04 太平洋康泰科学仪器(济南)有限公司 微针贴片给药组件及给药方法

Citations (3)

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WO2008115586A1 (en) * 2007-03-21 2008-09-25 Alza Corporation Apparatus and method for transdermal delivery of a triptan agonist
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス
WO2017143345A1 (en) * 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines

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US5169382A (en) 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
ES2195151T3 (es) 1996-06-18 2003-12-01 Alza Corp Dispositivo de mejora de aporte o de muestreo de agentes transdermicos.
US5738728A (en) 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5743960A (en) 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5741554A (en) 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US6083196A (en) 1997-12-11 2000-07-04 Alza Corporation Device for enhancing transdermal agent flux
US6322808B1 (en) 1997-12-11 2001-11-27 Alza Corporation Device for enhancing transdermal agent flux
DE69806963T2 (de) 1997-12-11 2002-11-21 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
ATE310561T1 (de) 1999-12-10 2005-12-15 Alza Corp Vorrichtung und verfahren zur verbesserung des mikronadel-haut-piercing
CZ20031035A3 (cs) 2000-10-13 2004-02-18 Alza Corporation Nárazový aplikátor opatřený množinou mikročepelek
IL155374A0 (en) 2000-10-13 2003-11-23 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
CA2425312C (en) 2000-10-13 2010-02-16 Alza Corporation Microprotrusion member retainer for impact applicator
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WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
US7963935B2 (en) 2001-04-20 2011-06-21 Alza Corporation Microprojection array having a beneficial agent containing coating
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008115586A1 (en) * 2007-03-21 2008-09-25 Alza Corporation Apparatus and method for transdermal delivery of a triptan agonist
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス
WO2017143345A1 (en) * 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KELLERMAN et al.: "Rapid systemic delivery of zolmitriptan using an adhesive dermally applied microarray", PAIN MANAGEMENT, 2017 July, vol. 7, no. 6, pages 559 - 567 *

Also Published As

Publication number Publication date
IL272776A (en) 2020-04-30
KR20200032170A (ko) 2020-03-25
JP2023033378A (ja) 2023-03-10
CA3223555A1 (en) 2019-02-28
JP7219384B2 (ja) 2023-02-08
IL272776B2 (en) 2024-06-01
IL272776B1 (en) 2024-02-01
WO2019040063A1 (en) 2019-02-28
CA3073442A1 (en) 2019-02-28
KR102340393B1 (ko) 2021-12-17
JP2021500397A (ja) 2021-01-07
KR20210155817A (ko) 2021-12-23
EP3672570A1 (en) 2020-07-01
AU2017428907A1 (en) 2020-03-05
CN111050749A (zh) 2020-04-21
CA3073442C (en) 2024-02-06

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Legal Events

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PC1 Assignment before grant (sect. 113)

Owner name: ZOSANO PHARMA CORPORATION

Free format text: FORMER APPLICANT(S): ZP OPCO, INC.

MK25 Application lapsed reg. 22.2i(2) - failure to pay acceptance fee