AU2017371416B2 - Nucleic acid-based assembly and use thereof in cancer therapy - Google Patents
Nucleic acid-based assembly and use thereof in cancer therapy Download PDFInfo
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- AU2017371416B2 AU2017371416B2 AU2017371416A AU2017371416A AU2017371416B2 AU 2017371416 B2 AU2017371416 B2 AU 2017371416B2 AU 2017371416 A AU2017371416 A AU 2017371416A AU 2017371416 A AU2017371416 A AU 2017371416A AU 2017371416 B2 AU2017371416 B2 AU 2017371416B2
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EP16202754.4 | 2016-12-07 | ||
EP16202754.4A EP3332812A1 (fr) | 2016-12-07 | 2016-12-07 | Ensemble à base d'acide nucléique et utilisation de l'ensemble dans la thérapie du cancer |
PCT/EP2017/081933 WO2018104492A1 (fr) | 2016-12-07 | 2017-12-07 | Assemblage à base d'acide nucléique, et utilisation de ce dernier dans le traitement du cancer |
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AU2017371416A1 AU2017371416A1 (en) | 2019-06-27 |
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US (1) | US20200123547A1 (fr) |
EP (2) | EP3332812A1 (fr) |
AU (1) | AU2017371416B2 (fr) |
CA (1) | CA3046280A1 (fr) |
IL (2) | IL308070A (fr) |
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WO2022120338A1 (fr) * | 2020-12-03 | 2022-06-09 | University Of Florida Research Foundation, Inc. | Assemblages d'aptamères pour la réticulation de protéines |
CN113248556B (zh) * | 2021-05-18 | 2022-07-26 | 武汉科技大学 | 一种核酸枝接偶氮苯的组装体及制备方法及应用 |
CN113567685B (zh) * | 2021-09-26 | 2022-05-17 | 瑞博奥(广州)生物科技股份有限公司 | 基于核酸适配体探针的hgfr识别方法及检测hgfr的试剂盒 |
CN113980959B (zh) * | 2021-10-27 | 2023-10-24 | 闽江学院 | 一种“y型”多功能dna纳米组装体、制备方法及其应用 |
CN116240213A (zh) * | 2022-08-10 | 2023-06-09 | 中山大学 | 光响应型核酸适配体、光启动dna聚合酶及应用 |
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WO2010071852A2 (fr) * | 2008-12-19 | 2010-06-24 | University Of Florida Research Foundation, Inc. | Micelles oligonucléotidiques |
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US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
US5853984A (en) | 1990-06-11 | 1998-12-29 | Nexstar Pharmaceuticals, Inc. | Use of nucleic acid ligands in flow cytometry |
US5580737A (en) | 1990-06-11 | 1996-12-03 | Nexstar Pharmaceuticals, Inc. | High-affinity nucleic acid ligands that discriminate between theophylline and caffeine |
US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
US5789163A (en) | 1990-06-11 | 1998-08-04 | Nexstar Pharmaceuticals, Inc. | Enzyme linked oligonucleotide assays (ELONAS) |
US5789157A (en) | 1990-06-11 | 1998-08-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue selex |
US5712375A (en) | 1990-06-11 | 1998-01-27 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue selex |
ES2110444T3 (es) | 1990-06-11 | 1998-02-16 | Nexstar Pharmaceuticals Inc | Ligandos de acidos nucleicos. |
US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
US5763566A (en) | 1990-06-11 | 1998-06-09 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue SELEX |
US5683867A (en) | 1990-06-11 | 1997-11-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: blended SELEX |
US5763177A (en) | 1990-06-11 | 1998-06-09 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex |
US5864026A (en) | 1990-06-11 | 1999-01-26 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue selex |
US5705337A (en) | 1990-06-11 | 1998-01-06 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chemi-SELEX |
US5637459A (en) | 1990-06-11 | 1997-06-10 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chimeric selex |
WO1996034875A1 (fr) | 1995-05-03 | 1996-11-07 | Nexstar Pharmaceuticals, Inc. | Evolution systematique des ligands par enrichissement exponentiel: procede selex pour tissus |
US6051698A (en) | 1997-06-06 | 2000-04-18 | Janjic; Nebojsa | Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes |
PT957929E (pt) | 1996-10-25 | 2006-06-30 | Gilead Sciences Inc | Complexos de ligandos de acido nucleico do factor de crescimento endotelial vascular |
US6506887B1 (en) | 1999-07-29 | 2003-01-14 | Somalogic, Incorporated | Conditional-selex |
EP1481090A4 (fr) | 2002-02-15 | 2006-08-09 | Somalogic Inc | Methodes et reactifs destines a la detection d'une liaison de cibles par des ligands d'acides nucleiques |
US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
KR101337684B1 (ko) * | 2011-10-17 | 2013-12-30 | 성균관대학교산학협력단 | 표적지향 및 치료가 가능한 다기능성 핵산 기반 항암제, 이의 제조 방법 및 이를 포함하는 항암제 조성물 |
JP6123794B2 (ja) * | 2012-03-28 | 2017-05-10 | 日本電気株式会社 | 標的物質の検出方法、検査キット、および検出装置 |
AU2015213483B2 (en) * | 2014-02-05 | 2020-07-02 | Deakin University | Aptamer construct |
WO2016050850A1 (fr) * | 2014-10-02 | 2016-04-07 | Guenter Mayer | Procédé d'identification ou de production d'un aptamère |
US10821189B2 (en) * | 2015-04-10 | 2020-11-03 | The Methodist Hospital System | CD38 ligand-drug conjugates for targeted cancer therapy |
US11572557B2 (en) * | 2018-01-29 | 2023-02-07 | The Board Of Trustees Of The Leland Stanford Junior University | Photoreversible acylation reagents |
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2016
- 2016-12-07 EP EP16202754.4A patent/EP3332812A1/fr not_active Withdrawn
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2017
- 2017-12-07 US US16/467,151 patent/US20200123547A1/en active Pending
- 2017-12-07 WO PCT/EP2017/081933 patent/WO2018104492A1/fr unknown
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- 2017-12-07 IL IL308070A patent/IL308070A/en unknown
- 2017-12-07 IL IL267155A patent/IL267155B2/en unknown
- 2017-12-07 CA CA3046280A patent/CA3046280A1/fr active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010071852A2 (fr) * | 2008-12-19 | 2010-06-24 | University Of Florida Research Foundation, Inc. | Micelles oligonucléotidiques |
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US20200123547A1 (en) | 2020-04-23 |
IL267155B2 (en) | 2024-04-01 |
IL308070A (en) | 2023-12-01 |
AU2017371416A1 (en) | 2019-06-27 |
EP3551229A1 (fr) | 2019-10-16 |
WO2018104492A1 (fr) | 2018-06-14 |
CA3046280A1 (fr) | 2018-06-14 |
EP3332812A1 (fr) | 2018-06-13 |
IL267155A (en) | 2019-08-29 |
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