AU2017324482A1 - Combining adenovirus and checkpoint inhibitors for treating cancer - Google Patents

Combining adenovirus and checkpoint inhibitors for treating cancer Download PDF

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Publication number
AU2017324482A1
AU2017324482A1 AU2017324482A AU2017324482A AU2017324482A1 AU 2017324482 A1 AU2017324482 A1 AU 2017324482A1 AU 2017324482 A AU2017324482 A AU 2017324482A AU 2017324482 A AU2017324482 A AU 2017324482A AU 2017324482 A1 AU2017324482 A1 AU 2017324482A1
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AU
Australia
Prior art keywords
oncos
cancer
adenovirus
tumor
virus
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2017324482A
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English (en)
Inventor
Elina HAAVISTO
Magnus JÄDERBERG
Lukasz KURYK
Sari Pesonen
Tuuli RANKI
Antti Vuolanto
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Targovax Oy
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Targovax Oy
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Filing date
Publication date
Application filed by Targovax Oy filed Critical Targovax Oy
Publication of AU2017324482A1 publication Critical patent/AU2017324482A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2017324482A 2016-09-12 2017-09-11 Combining adenovirus and checkpoint inhibitors for treating cancer Abandoned AU2017324482A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16188301.2 2016-09-12
EP16188301.2A EP3293201B1 (en) 2016-09-12 2016-09-12 Combining adenovirus and checkpoint inhibitors for treating cancer
PCT/FI2017/050645 WO2018046803A1 (en) 2016-09-12 2017-09-11 Combining adenovirus and checkpoint inhibitors for treating cancer

Publications (1)

Publication Number Publication Date
AU2017324482A1 true AU2017324482A1 (en) 2019-04-11

Family

ID=56926041

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017324482A Abandoned AU2017324482A1 (en) 2016-09-12 2017-09-11 Combining adenovirus and checkpoint inhibitors for treating cancer

Country Status (14)

Country Link
US (2) US10940203B2 (enExample)
EP (2) EP3293201B1 (enExample)
JP (2) JP7146739B2 (enExample)
CN (1) CN109715664A (enExample)
AU (1) AU2017324482A1 (enExample)
DK (1) DK3293201T3 (enExample)
ES (1) ES2845690T3 (enExample)
HR (1) HRP20210133T1 (enExample)
HU (1) HUE053236T2 (enExample)
LT (1) LT3293201T (enExample)
PL (1) PL3293201T3 (enExample)
PT (1) PT3293201T (enExample)
SI (1) SI3293201T1 (enExample)
WO (1) WO2018046803A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10350275B2 (en) * 2013-09-21 2019-07-16 Advantagene, Inc. Methods of cytotoxic gene therapy to treat tumors
US11090344B2 (en) 2016-05-27 2021-08-17 Dnatrix, Inc. Adenovirus and immunomodulator combination therapy
WO2018085461A1 (en) * 2016-11-01 2018-05-11 Dnatrix, Inc. Combination therapy for treatment of brain cancers
GB201804473D0 (en) * 2018-03-21 2018-05-02 Valo Therapeutics Oy Modified oncolytic adenoviruses
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
IL293051A (en) 2019-11-18 2022-07-01 Janssen Biotech Inc Vaccines based on mutant calr and jak2 and their uses
US12295997B2 (en) 2020-07-06 2025-05-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
CN114426945B (zh) * 2021-11-10 2024-08-23 西安交通大学医学院第一附属医院 胶质瘤类器官原代促活液、培养液及制备、培养方法
WO2024207425A1 (en) * 2023-04-07 2024-10-10 Virogin Biotech (Shanghai) Ltd. Combination of recombinant oncolytic virus and checkpoint inhibitor for the treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2304281B1 (es) * 2006-02-01 2009-08-12 Dnatrix Inc. Adenovirus oncoliticos para el tratamiento del cancer.
HUE031689T2 (en) 2008-12-22 2017-07-28 Targovax Oy Oncolytic adenoviral vectors and related procedures and applications
FI20090030A0 (fi) * 2009-02-02 2009-02-02 Akseli Eetu Hemminki Onkolyyttiset virukset
ES2871910T3 (es) 2012-08-30 2021-11-02 Amgen Inc Un método para tratar el melanoma usando un virus de herpes simple y un inhibidor de puntos de control inmunitario
WO2014047350A1 (en) 2012-09-20 2014-03-27 Morningside Technology Ventures Ltd. Oncolytic virus encoding pd-1 binding agents and uses of the same
US10350275B2 (en) 2013-09-21 2019-07-16 Advantagene, Inc. Methods of cytotoxic gene therapy to treat tumors
CN106029889A (zh) * 2013-11-22 2016-10-12 德那翠丝有限公司 表达免疫细胞刺激受体激动剂的腺病毒

Also Published As

Publication number Publication date
HUE053236T2 (hu) 2021-06-28
HRP20210133T1 (hr) 2021-03-19
JP2019532047A (ja) 2019-11-07
EP3783032A1 (en) 2021-02-24
DK3293201T3 (da) 2020-12-07
US20210121564A1 (en) 2021-04-29
EP3293201B1 (en) 2020-11-04
CN109715664A (zh) 2019-05-03
US20190201525A1 (en) 2019-07-04
PT3293201T (pt) 2020-12-07
LT3293201T (lt) 2021-03-25
US10940203B2 (en) 2021-03-09
EP3293201A1 (en) 2018-03-14
JP7146739B2 (ja) 2022-10-04
WO2018046803A1 (en) 2018-03-15
SI3293201T1 (sl) 2021-03-31
US11690913B2 (en) 2023-07-04
PL3293201T3 (pl) 2021-06-14
JP2022183170A (ja) 2022-12-08
ES2845690T3 (es) 2021-07-27

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application