DK3293201T3 - Kombinering af adenovirus og checkpoint-inhibitorer til behandling af cancer - Google Patents
Kombinering af adenovirus og checkpoint-inhibitorer til behandling af cancer Download PDFInfo
- Publication number
- DK3293201T3 DK3293201T3 DK16188301.2T DK16188301T DK3293201T3 DK 3293201 T3 DK3293201 T3 DK 3293201T3 DK 16188301 T DK16188301 T DK 16188301T DK 3293201 T3 DK3293201 T3 DK 3293201T3
- Authority
- DK
- Denmark
- Prior art keywords
- adenovirus
- cancer
- treatment
- combination
- checkpoint inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16188301.2A EP3293201B1 (en) | 2016-09-12 | 2016-09-12 | Combining adenovirus and checkpoint inhibitors for treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3293201T3 true DK3293201T3 (da) | 2020-12-07 |
Family
ID=56926041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16188301.2T DK3293201T3 (da) | 2016-09-12 | 2016-09-12 | Kombinering af adenovirus og checkpoint-inhibitorer til behandling af cancer |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10940203B2 (enExample) |
| EP (2) | EP3783032A1 (enExample) |
| JP (2) | JP7146739B2 (enExample) |
| CN (1) | CN109715664A (enExample) |
| AU (1) | AU2017324482A1 (enExample) |
| DK (1) | DK3293201T3 (enExample) |
| ES (1) | ES2845690T3 (enExample) |
| HR (1) | HRP20210133T1 (enExample) |
| HU (1) | HUE053236T2 (enExample) |
| LT (1) | LT3293201T (enExample) |
| PL (1) | PL3293201T3 (enExample) |
| PT (1) | PT3293201T (enExample) |
| SI (1) | SI3293201T1 (enExample) |
| WO (1) | WO2018046803A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10350275B2 (en) * | 2013-09-21 | 2019-07-16 | Advantagene, Inc. | Methods of cytotoxic gene therapy to treat tumors |
| US11090344B2 (en) | 2016-05-27 | 2021-08-17 | Dnatrix, Inc. | Adenovirus and immunomodulator combination therapy |
| EP3534923A4 (en) * | 2016-11-01 | 2020-05-27 | DNAtrix, Inc. | COMBINATION THERAPY FOR THE TREATMENT OF BRAIN CARCINOMAS |
| GB201804473D0 (en) * | 2018-03-21 | 2018-05-02 | Valo Therapeutics Oy | Modified oncolytic adenoviruses |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| EP4061405A1 (en) | 2019-11-18 | 2022-09-28 | Janssen Biotech, Inc. | Vaccines based on mutant calr and jak2 and their uses |
| EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| WO2022009049A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| CN114426945B (zh) * | 2021-11-10 | 2024-08-23 | 西安交通大学医学院第一附属医院 | 胶质瘤类器官原代促活液、培养液及制备、培养方法 |
| CN121335710A (zh) * | 2023-04-07 | 2026-01-13 | 上海复诺健生物科技有限公司 | 重组溶瘤病毒与检查点抑制剂的组合用于治疗癌症 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2304281B1 (es) * | 2006-02-01 | 2009-08-12 | Dnatrix Inc. | Adenovirus oncoliticos para el tratamiento del cancer. |
| BRPI0924123B8 (pt) | 2008-12-22 | 2021-05-25 | Oncos Therapeutics Oy | vetores adenovirais oncolíticos, usos dos mesmos, composição farmacêutica e método para produzir gmcsf em uma célula in vitro |
| FI20090030A0 (fi) * | 2009-02-02 | 2009-02-02 | Akseli Eetu Hemminki | Onkolyyttiset virukset |
| EA201590451A1 (ru) | 2012-08-30 | 2016-05-31 | Эмджен Инк. | Способ лечения меланомы с применением вируса простого герпеса и ингибитора иммунной контрольной точки |
| US20150250837A1 (en) | 2012-09-20 | 2015-09-10 | Morningside Technology Ventures Ltd. | Oncolytic virus encoding pd-1 binding agents and uses of the same |
| US10350275B2 (en) | 2013-09-21 | 2019-07-16 | Advantagene, Inc. | Methods of cytotoxic gene therapy to treat tumors |
| CN114317461A (zh) * | 2013-11-22 | 2022-04-12 | 德那翠丝有限公司 | 表达免疫细胞刺激受体激动剂的腺病毒 |
-
2016
- 2016-09-12 EP EP20197744.4A patent/EP3783032A1/en not_active Withdrawn
- 2016-09-12 PT PT161883012T patent/PT3293201T/pt unknown
- 2016-09-12 LT LTEP16188301.2T patent/LT3293201T/lt unknown
- 2016-09-12 SI SI201631076T patent/SI3293201T1/sl unknown
- 2016-09-12 PL PL16188301T patent/PL3293201T3/pl unknown
- 2016-09-12 DK DK16188301.2T patent/DK3293201T3/da active
- 2016-09-12 HU HUE16188301A patent/HUE053236T2/hu unknown
- 2016-09-12 ES ES16188301T patent/ES2845690T3/es active Active
- 2016-09-12 EP EP16188301.2A patent/EP3293201B1/en active Active
-
2017
- 2017-09-11 JP JP2019513967A patent/JP7146739B2/ja not_active Expired - Fee Related
- 2017-09-11 US US16/330,274 patent/US10940203B2/en not_active Expired - Fee Related
- 2017-09-11 AU AU2017324482A patent/AU2017324482A1/en not_active Abandoned
- 2017-09-11 WO PCT/FI2017/050645 patent/WO2018046803A1/en not_active Ceased
- 2017-09-11 CN CN201780055920.5A patent/CN109715664A/zh active Pending
-
2021
- 2021-01-05 US US17/141,463 patent/US11690913B2/en active Active
- 2021-01-26 HR HRP20210133TT patent/HRP20210133T1/hr unknown
-
2022
- 2022-09-21 JP JP2022150036A patent/JP2022183170A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| LT3293201T (lt) | 2021-03-25 |
| EP3293201A1 (en) | 2018-03-14 |
| WO2018046803A1 (en) | 2018-03-15 |
| CN109715664A (zh) | 2019-05-03 |
| US20210121564A1 (en) | 2021-04-29 |
| HUE053236T2 (hu) | 2021-06-28 |
| JP2019532047A (ja) | 2019-11-07 |
| EP3783032A1 (en) | 2021-02-24 |
| US20190201525A1 (en) | 2019-07-04 |
| JP2022183170A (ja) | 2022-12-08 |
| US10940203B2 (en) | 2021-03-09 |
| AU2017324482A1 (en) | 2019-04-11 |
| PL3293201T3 (pl) | 2021-06-14 |
| US11690913B2 (en) | 2023-07-04 |
| SI3293201T1 (sl) | 2021-03-31 |
| JP7146739B2 (ja) | 2022-10-04 |
| PT3293201T (pt) | 2020-12-07 |
| HRP20210133T1 (hr) | 2021-03-19 |
| EP3293201B1 (en) | 2020-11-04 |
| ES2845690T3 (es) | 2021-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3558997T3 (da) | Aminotriazolopyridinforbindelser og deres anvendelse til behandling af cancer | |
| DK3331915T3 (da) | Immun-checkpoint-inhibitorer til anvendelse til behandling af blodbårne cancere | |
| DK3678668T3 (da) | ENPP1-inhibitorer og deres anvendelse til behandling af kræft | |
| DK3336197T3 (da) | Epigenetiske markører og relaterede fremgangsmåder og midler til detektion og behandling af ovariekræft | |
| DK3600281T3 (da) | Kombinationsbehandling til behandling eller forebyggelse af tumorer | |
| DK3368069T3 (da) | Anvendelse af myostatininhibitorer og kombinationsterapier | |
| DK3285809T3 (da) | Inhibitorer af immunkontrolpunktsmodulatorer til anvendelse i behandling af kræft og infektioner. | |
| DK3445388T3 (da) | Materialer og fremgangsmåder til behandling af hæmoglobinopatier | |
| DK3508502T5 (da) | Kombination af anti-lag-3-antistoffer og anti-pd-1-antistoffer til behandling af tumorer | |
| DK3096798T3 (da) | Plasmakallikreinbindende proteiner og anvendelser deraf til behandling af hereditært angioødem | |
| DK3242947T3 (da) | Genterapi og elektroporese til behandling af maligniteter | |
| DK3102673T3 (da) | Fremgangsmåder og sammensætninger til behandling af beta-talassæmi | |
| DK3189074T3 (da) | Sammensætninger og metoder til behandling og forebyggelse af inflammation | |
| DK3362066T3 (da) | Kombinationsterapi til behandling af maligniteter | |
| DK3200815T3 (da) | Fremgangsmåder og sammensætninger til behandling af cancer | |
| DK3245193T3 (da) | Heterocycliske forbindelser til billedscanning og behandling af cancer samt fremgangsmåder til anvendelse af disse | |
| DK3416957T3 (da) | 6-heterocyclyl-4-morpholin-4-ylpyridin-2-on-forbindelser anvendelige ved behandlingen af cancer og diabetes | |
| DK3174559T3 (da) | Radiomærkede antistoffragmenter til anvendelse inden for forebyggelsen og/eller behandlingen af cancer | |
| IL261047A (en) | Taf1 inhibitors for the therapy of cancer | |
| DK3807316T3 (da) | Sammensætninger og fremgangsmåder til behandling af cancer | |
| DK2994157T3 (da) | Tafa4-forbindelser og anvendelser deraf til behandling af smerte | |
| DK3790879T3 (da) | Triazolopyrimidinforbindelser og deres anvendelse til behandling af kræft | |
| DK3374497T3 (da) | Modificerede makrofager til anvendelse i behandlingen af kræft | |
| PL3293201T3 (pl) | Łączenie adenowirusa i inhibitorów punktów kontrolnych do leczenia nowotworu | |
| DK3522873T3 (da) | Sammensætninger og fremgangsmåder til behandlingen af xerostomi |