AU2017254702B2 - Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use - Google Patents

Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use Download PDF

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AU2017254702B2
AU2017254702B2 AU2017254702A AU2017254702A AU2017254702B2 AU 2017254702 B2 AU2017254702 B2 AU 2017254702B2 AU 2017254702 A AU2017254702 A AU 2017254702A AU 2017254702 A AU2017254702 A AU 2017254702A AU 2017254702 B2 AU2017254702 B2 AU 2017254702B2
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cancer
alkyl
disease
cdk9
bifunctional compound
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AU2017254702A1 (en
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Nathanael Gray
Nicholas KWIATKOWSKI
Yanke LIANG
Calla M. OLSON
Tinghu Zhang
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Dana Farber Cancer Institute Inc
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AU2017254702A 2016-04-22 2017-04-21 Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use Active AU2017254702B2 (en)

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US201662326581P 2016-04-22 2016-04-22
US62/326,581 2016-04-22
PCT/US2017/028924 WO2017185023A1 (en) 2016-04-22 2017-04-21 Degradation of cyclin-dependent kinase 9 (cdk9) by conjugation of cdk9 inhibitors with e3 ligase ligand and methods of use

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US10632209B2 (en) * 2017-11-10 2020-04-28 The Regents Of The University Of Michigan ASH1L inhibitors and methods of treatment therewith
US20200377477A1 (en) * 2018-02-20 2020-12-03 Dana-Farber Cancer Institute, Inc. Degraders of egfr and methods of use thereof
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CN118754858A (zh) 2018-03-26 2024-10-11 诺华股份有限公司 N-(3-(7H-吡咯并[2,3-d]嘧啶-4-基)苯基)苯甲酰胺衍生物
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