AU2017254702B2 - Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use - Google Patents
Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use Download PDFInfo
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- AU2017254702B2 AU2017254702B2 AU2017254702A AU2017254702A AU2017254702B2 AU 2017254702 B2 AU2017254702 B2 AU 2017254702B2 AU 2017254702 A AU2017254702 A AU 2017254702A AU 2017254702 A AU2017254702 A AU 2017254702A AU 2017254702 B2 AU2017254702 B2 AU 2017254702B2
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326581P | 2016-04-22 | 2016-04-22 | |
| US62/326,581 | 2016-04-22 | ||
| PCT/US2017/028924 WO2017185023A1 (en) | 2016-04-22 | 2017-04-21 | Degradation of cyclin-dependent kinase 9 (cdk9) by conjugation of cdk9 inhibitors with e3 ligase ligand and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2017254702A1 AU2017254702A1 (en) | 2018-10-11 |
| AU2017254702B2 true AU2017254702B2 (en) | 2020-12-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017254702A Active AU2017254702B2 (en) | 2016-04-22 | 2017-04-21 | Degradation of cyclin-dependent kinase 9 (CDK9) by conjugation of CDK9 inhibitors with E3 ligase ligand and methods of use |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10532103B2 (enExample) |
| EP (1) | EP3445760B1 (enExample) |
| JP (1) | JP6927999B2 (enExample) |
| CN (1) | CN109153675B (enExample) |
| AU (1) | AU2017254702B2 (enExample) |
| CA (1) | CA3018429A1 (enExample) |
| WO (1) | WO2017185023A1 (enExample) |
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| US11173211B2 (en) | 2016-12-23 | 2021-11-16 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides |
| US10513515B2 (en) | 2017-08-25 | 2019-12-24 | Biotheryx, Inc. | Ether compounds and uses thereof |
| JP7424637B2 (ja) | 2017-11-10 | 2024-01-30 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Ash1l分解剤及びそれを用いた治療方法 |
| AU2019225806A1 (en) * | 2018-02-20 | 2020-07-16 | Dana-Farber Cancer Institute, Inc. | Inhibitors of EGFR and methods of use thereof |
| EP3755698A4 (en) * | 2018-02-20 | 2021-10-27 | Dana-Farber Cancer Institute, Inc. | EGFR DEGRADATION AGENTS AND METHODS FOR USING THEM |
| EP3755697A4 (en) * | 2018-02-20 | 2021-10-27 | Dana-Farber Cancer Institute, Inc. | EGFR DEGRADATION AGENTS AND METHODS FOR USING THEM |
| EP4166557A1 (en) | 2018-03-26 | 2023-04-19 | Novartis AG | Intermediates of n-(3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)benzamide derivatives |
| US11236103B2 (en) | 2018-07-27 | 2022-02-01 | Biotheryx, Inc. | Bifunctional compounds |
| WO2020041331A1 (en) | 2018-08-20 | 2020-02-27 | Arvinas Operations, Inc. | Proteolysis targeting chimeric (protac) compound with e3 ubiquitin ligase binding activity and targeting alpha-synuclein protein for treating neurodegenerative diseases |
| WO2020093370A1 (zh) * | 2018-11-09 | 2020-05-14 | 汪义朋 | 一种特异性降解tau蛋白的小分子化合物及其应用 |
| WO2020102195A1 (en) | 2018-11-13 | 2020-05-22 | Biotheryx, Inc. | Substituted isoindolinones |
| US20230073777A1 (en) * | 2019-02-27 | 2023-03-09 | Cullgen (Shanghai), Inc. | Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use |
| EP3941607A1 (en) | 2019-03-21 | 2022-01-26 | Codiak BioSciences, Inc. | Process for preparing extracellular vesicles |
| CA3133314A1 (en) | 2019-03-21 | 2020-09-24 | Codiak Biosciences, Inc. | Extracellular vesicle conjugates and uses thereof |
| WO2020206137A1 (en) | 2019-04-04 | 2020-10-08 | Dana-Farber Cancer Institute, Inc. | Cdk2/5 degraders and uses thereof |
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