AU2016315952A1 - Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation damage - Google Patents

Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation damage Download PDF

Info

Publication number
AU2016315952A1
AU2016315952A1 AU2016315952A AU2016315952A AU2016315952A1 AU 2016315952 A1 AU2016315952 A1 AU 2016315952A1 AU 2016315952 A AU2016315952 A AU 2016315952A AU 2016315952 A AU2016315952 A AU 2016315952A AU 2016315952 A1 AU2016315952 A1 AU 2016315952A1
Authority
AU
Australia
Prior art keywords
subject
sdg
radiation
administering
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016315952A
Other languages
English (en)
Inventor
Melpo Christofidou-Solomidou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of AU2016315952A1 publication Critical patent/AU2016315952A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/55Linaceae (Flax family), e.g. Linum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AU2016315952A 2015-09-01 2016-08-31 Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation damage Abandoned AU2016315952A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562212898P 2015-09-01 2015-09-01
US62/212,898 2015-09-01
PCT/US2016/049780 WO2017040718A1 (en) 2015-09-01 2016-08-31 USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION DAMAGE

Publications (1)

Publication Number Publication Date
AU2016315952A1 true AU2016315952A1 (en) 2018-04-05

Family

ID=58188252

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016315952A Abandoned AU2016315952A1 (en) 2015-09-01 2016-08-31 Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation damage

Country Status (10)

Country Link
US (1) US20180243327A1 (enExample)
EP (1) EP3344271A4 (enExample)
JP (1) JP2018528208A (enExample)
KR (1) KR20180041742A (enExample)
CN (1) CN108697748A (enExample)
AU (1) AU2016315952A1 (enExample)
CA (1) CA2997112A1 (enExample)
IL (1) IL257780A (enExample)
MA (1) MA45520A (enExample)
WO (1) WO2017040718A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200268779A1 (en) * 2017-09-27 2020-08-27 The Trustees Of The University Of Pennsylvania USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION-INDUCED CARDIOVASCULAR DYSFUNCTION

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3065925B2 (ja) * 1996-01-30 2000-07-17 日清製油株式会社 活性酸素種消去剤及び退色防止剤
US20040156881A1 (en) * 2001-04-04 2004-08-12 Aedin Cassidy Use of lignans in foods
US7351739B2 (en) * 2004-04-30 2008-04-01 Wellgen, Inc. Bioactive compounds and methods of uses thereof
US7776915B2 (en) * 2005-03-24 2010-08-17 Tracie Martyn International, Llc Topical formulations and methods of use
US10045951B2 (en) * 2007-05-25 2018-08-14 The Trustees Of The University Of Pennsylvania Flaxseed lignan complex and its use thereof
US10449224B2 (en) * 2007-05-25 2019-10-22 The Trustees Of The University Of Pennsylvania Flaxseed lignan complex, methods of using and compositions thereof
AU2009279676C1 (en) * 2008-08-07 2015-08-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Radioprotectants targeting thrombospondin-1 and CD47
US8575563B2 (en) * 2009-11-02 2013-11-05 Procure Treatment Centers, Inc. Compact isocentric gantry
PT3007557T (pt) * 2013-06-10 2018-11-09 Scripps Research Inst Preparação do diglucosídeo (s,s)-secoisolariciresinol e do diglucosídeo (r,r)-secoisolariciresinol

Also Published As

Publication number Publication date
KR20180041742A (ko) 2018-04-24
CA2997112A1 (en) 2017-03-09
MA45520A (fr) 2019-05-08
IL257780A (en) 2018-04-30
US20180243327A1 (en) 2018-08-30
CN108697748A (zh) 2018-10-23
EP3344271A1 (en) 2018-07-11
JP2018528208A (ja) 2018-09-27
WO2017040718A1 (en) 2017-03-09
EP3344271A4 (en) 2019-05-08

Similar Documents

Publication Publication Date Title
Laila et al. Wound healing effect of Haruan (Channa striatus) spray
US20250177368A1 (en) Radiation mitigator and method of use thereof
US9993455B2 (en) Method of mitigating long term detrimental effects of exposure to medical imaging ionizing radiation by administration of genistein
CN112437673A (zh) 亚砜类化合物在预防放射性神经系统疾病中的用途
WO2017177479A1 (zh) 丁香醛在制备电离辐射致肠道损伤防护药物中的应用
US20180243327A1 (en) USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION DAMAGE
US10639296B2 (en) Methods to mitigate injury from radiation exposure
WO2014106473A1 (zh) 甘草次酸、甘草酸在制备预防或治疗放射性软组织损伤药物中的应用
CN118512594A (zh) Parp1抑制剂在制备辐射损伤修复药物中的应用
CN110354133A (zh) 四氢生物蝶呤的应用及药物
HK1262581A1 (en) USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION DAMAGE
US20200268779A1 (en) USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION-INDUCED CARDIOVASCULAR DYSFUNCTION
CN114081880B (zh) 木香内酯及其衍生物在制备预防和/或治疗肠损伤的药物中的用途
Yang et al. Pharmacokinetic evaluation and bioavailability of KPT-335 (Verdinexor) in cats
KR20200137294A (ko) 플로로탄닌을 포함하는 방사선에 의한 피부질환 예방, 개선 또는 치료용 조성물
RU2832338C1 (ru) Инъекционный раствор, содержащий п-боронофенилаланин
CN119564713A (zh) 松果菊苷在制备预防或治疗辐射损伤的药物中的用途
CN104523735A (zh) 灯盏花素在制备预防和治疗电离辐射损伤药物方面的应用
JP2018528208A5 (enExample)
WO2015195894A1 (en) Methods and compositions for the modulation of beta-endorphin levels
Shin et al. A comparative study of radioprotection with Callophyllis japonica extract and amifostine against lethal whole body gamma irradiation in mice
AU2012289763B2 (en) Intrathecal or epidural administration of 3-[(1S,2S)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol
CN119385999A (zh) 壬二酸在制备防治放射性肺损伤药物中的应用
CN104623044A (zh) 鱼腥草在制备预防和治疗电离辐射损伤药物方面的应用
CN110559305A (zh) 唾液酸在制备电离辐射致肠道或dna损伤防护药物中的应用

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application