AU2016294417B2 - Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy - Google Patents

Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy Download PDF

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AU2016294417B2
AU2016294417B2 AU2016294417A AU2016294417A AU2016294417B2 AU 2016294417 B2 AU2016294417 B2 AU 2016294417B2 AU 2016294417 A AU2016294417 A AU 2016294417A AU 2016294417 A AU2016294417 A AU 2016294417A AU 2016294417 B2 AU2016294417 B2 AU 2016294417B2
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antibody
disease
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sequence
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AU2016294417A1 (en
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Arron HEARN
Robert George Edward Holgate
Jay ROTHSTEIN
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Immunext Inc
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Immunext Inc
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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AU2016294417A 2015-07-14 2016-07-13 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy Active AU2016294417B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022263520A AU2022263520B2 (en) 2015-07-14 2022-11-02 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy
AU2025226796A AU2025226796A1 (en) 2015-07-14 2025-09-05 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562192269P 2015-07-14 2015-07-14
US62/192,269 2015-07-14
US201562197966P 2015-07-28 2015-07-28
US62/197,966 2015-07-28
US201662277201P 2016-01-11 2016-01-11
US62/277,201 2016-01-11
PCT/US2016/042074 WO2017011544A1 (en) 2015-07-14 2016-07-13 Anti-cd154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy

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AU2022263520A Division AU2022263520B2 (en) 2015-07-14 2022-11-02 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy

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AU2016294417A1 AU2016294417A1 (en) 2018-03-08
AU2016294417B2 true AU2016294417B2 (en) 2022-08-04

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AU2016294417A Active AU2016294417B2 (en) 2015-07-14 2016-07-13 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy
AU2022263520A Active AU2022263520B2 (en) 2015-07-14 2022-11-02 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy
AU2025226796A Pending AU2025226796A1 (en) 2015-07-14 2025-09-05 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy

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AU2022263520A Active AU2022263520B2 (en) 2015-07-14 2022-11-02 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy
AU2025226796A Pending AU2025226796A1 (en) 2015-07-14 2025-09-05 Anti-CD154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy

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US (3) US10874738B2 (enExample)
EP (1) EP3331548A4 (enExample)
JP (4) JP6826113B2 (enExample)
KR (2) KR20250099272A (enExample)
CN (2) CN114671952A (enExample)
AU (3) AU2016294417B2 (enExample)
CL (1) CL2018000103A1 (enExample)
CO (1) CO2018001363A2 (enExample)
CR (1) CR20180097A (enExample)
DO (1) DOP2018000018A (enExample)
EA (1) EA201890297A1 (enExample)
EC (1) ECSP18009949A (enExample)
GT (1) GT201800018A (enExample)
HK (1) HK1249735A1 (enExample)
IL (3) IL310460A (enExample)
MX (2) MX2018000548A (enExample)
MY (2) MY196991A (enExample)
PE (1) PE20180741A1 (enExample)
PH (1) PH12018500098A1 (enExample)
SG (1) SG10201913431QA (enExample)
TN (1) TN2018000021A1 (enExample)
WO (1) WO2017011544A1 (enExample)

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WO2024222895A1 (zh) 2023-04-28 2024-10-31 信达生物制药(苏州)有限公司 抗cd40l抗体及其在人自身免疫疾病治疗的应用

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CR20180097A (es) * 2015-07-14 2018-05-25 Immunext Inc Anticuerpo anti-cd154 con caracteristicas de unión, funcionalidad y seguridad mejoradas y uso en inmunoterapia humana
RU2018122255A (ru) 2015-11-27 2019-12-19 Аблинкс Нв Полипептиды, ингибирующие cd40l
CA3096222A1 (en) 2018-04-06 2019-10-10 Atyr Pharma, Inc. Compositions and methods comprising anti-nrp2 antibodies
WO2020056162A1 (en) * 2018-09-12 2020-03-19 Oregon Health & Science University Detecting and/or subtyping circulating hybrid cells that correlate with stage and survival
US20210317220A1 (en) * 2018-09-24 2021-10-14 Janssen Biotech, Inc. Method of providing safe administration of an anti-cd154 antibody
CN109453383A (zh) * 2018-11-12 2019-03-12 陈慧慧 免疫检查点的抑制剂在制备治疗青光眼及其他眼部免疫损伤机制相关疾病药物中的应用
CN114173772A (zh) * 2019-04-12 2022-03-11 托尼克斯医药控股公司 Cd40-cd154结合的抑制剂
JP7701913B2 (ja) 2019-10-03 2025-07-02 エータイアー ファーマ， インコーポレイテッド 抗ｎｒｐ２抗体を含む組成物および方法
CN113488170B (zh) * 2021-07-02 2023-07-25 温州医科大学 急性前葡萄膜炎复发风险预测模型构建方法及相关设备
CN117715941A (zh) * 2021-07-30 2024-03-15 首尔大学校产学协力团 抗cd154抗体及其用途
JP2024527947A (ja) * 2021-07-30 2024-07-26 ソウル ナショナル ユニバーシティ アールアンドディービー ファウンデーション 抗ｃｄ１５４抗体及びその用途
WO2024211211A1 (en) 2023-04-03 2024-10-10 Regeneron Pharmaceuticals, Inc. Methods of improving transplant survival using il-2 receptor gamma chain antibodies
US20240392022A1 (en) 2023-05-22 2024-11-28 Genzyme Corporation Treatment of multiple sclerosis with anti-cd40l antibodies

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WO2008118356A2 (en) * 2007-03-22 2008-10-02 Biogen Idec Ma Inc. Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof
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