AU2016280696B2 - Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same - Google Patents

Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same Download PDF

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Publication number
AU2016280696B2
AU2016280696B2 AU2016280696A AU2016280696A AU2016280696B2 AU 2016280696 B2 AU2016280696 B2 AU 2016280696B2 AU 2016280696 A AU2016280696 A AU 2016280696A AU 2016280696 A AU2016280696 A AU 2016280696A AU 2016280696 B2 AU2016280696 B2 AU 2016280696B2
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Prior art keywords
lactate
sensor
stabilizing agent
oxidase
sensor according
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AU2016280696A1 (en
Inventor
Kuan-Chou Chen
Benjamin J. Feldman
Tianmei Ouyang
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Abbott Diabetes Care Inc
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Abbott Diabetes Care Inc
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Priority to AU2022201057A priority Critical patent/AU2022201057B2/en
Priority to AU2024204622A priority patent/AU2024204622A1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01—Peroxidases (1.11.1)
    • C12Y111/01006—Catalase (1.11.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12004—Lactate 2-monooxygenase (1.13.12.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Spectroscopy & Molecular Physics (AREA)
AU2016280696A 2015-06-15 2016-06-15 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same Active AU2016280696B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022201057A AU2022201057B2 (en) 2015-06-15 2022-02-17 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
AU2024204622A AU2024204622A1 (en) 2015-06-15 2024-07-03 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562175910P 2015-06-15 2015-06-15
US62/175,910 2015-06-15
PCT/US2016/037642 WO2016205378A1 (en) 2015-06-15 2016-06-15 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same

Related Child Applications (1)

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AU2022201057A Division AU2022201057B2 (en) 2015-06-15 2022-02-17 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same

Publications (2)

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AU2016280696A1 AU2016280696A1 (en) 2017-12-07
AU2016280696B2 true AU2016280696B2 (en) 2021-11-18

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AU2016280696A Active AU2016280696B2 (en) 2015-06-15 2016-06-15 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
AU2022201057A Active AU2022201057B2 (en) 2015-06-15 2022-02-17 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
AU2024204622A Pending AU2024204622A1 (en) 2015-06-15 2024-07-03 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same

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AU2022201057A Active AU2022201057B2 (en) 2015-06-15 2022-02-17 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
AU2024204622A Pending AU2024204622A1 (en) 2015-06-15 2024-07-03 Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same

Country Status (8)

Country Link
US (2) US9914952B2 (https=)
EP (3) EP4647504A3 (https=)
JP (1) JP6822981B2 (https=)
CN (1) CN107735027A (https=)
AU (3) AU2016280696B2 (https=)
CA (1) CA2987091A1 (https=)
ES (1) ES2882631T3 (https=)
WO (1) WO2016205378A1 (https=)

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EP3790465A1 (en) * 2018-05-08 2021-03-17 Abbott Diabetes Care Inc. Sensing systems and methods for identifying emotional stress events
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Also Published As

Publication number Publication date
ES2882631T3 (es) 2021-12-02
US10392647B2 (en) 2019-08-27
CA2987091A1 (en) 2016-12-22
EP4647504A3 (en) 2026-02-18
AU2022201057A1 (en) 2022-03-10
EP3967227B1 (en) 2025-07-30
AU2024204622A1 (en) 2024-07-18
JP6822981B2 (ja) 2021-01-27
EP3307164B1 (en) 2021-05-12
JP2018519507A (ja) 2018-07-19
EP3967227A1 (en) 2022-03-16
EP3307164A1 (en) 2018-04-18
AU2016280696A1 (en) 2017-12-07
US20180148758A1 (en) 2018-05-31
EP4647504A2 (en) 2025-11-12
US9914952B2 (en) 2018-03-13
AU2022201057B2 (en) 2024-04-04
CN107735027A (zh) 2018-02-23
EP3307164A4 (en) 2018-11-21
US20160362716A1 (en) 2016-12-15
WO2016205378A1 (en) 2016-12-22

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