AU2016215035A1 - Compounds and uses in treatment of senescence-associated conditions - Google Patents

Compounds and uses in treatment of senescence-associated conditions Download PDF

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Publication number
AU2016215035A1
AU2016215035A1 AU2016215035A AU2016215035A AU2016215035A1 AU 2016215035 A1 AU2016215035 A1 AU 2016215035A1 AU 2016215035 A AU2016215035 A AU 2016215035A AU 2016215035 A AU2016215035 A AU 2016215035A AU 2016215035 A1 AU2016215035 A1 AU 2016215035A1
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alkyl
compound
salt
disease
group
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AU2016215035A
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Inventor
Nathaniel David
Remi-Martin LABERGE
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Buck Institute for Research on Aging
Unity Biotechnology Inc
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Buck Institute for Research on Aging
Unity Biotechnology Inc
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  • Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
AU2016215035A 2015-02-06 2016-02-05 Compounds and uses in treatment of senescence-associated conditions Abandoned AU2016215035A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113227P 2015-02-06 2015-02-06
US62/113,227 2015-02-06
PCT/US2016/016894 WO2016127135A1 (en) 2015-02-06 2016-02-05 Compounds and uses in treatment of senescence-associated conditons

Publications (1)

Publication Number Publication Date
AU2016215035A1 true AU2016215035A1 (en) 2017-09-28

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ID=56564790

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016215035A Abandoned AU2016215035A1 (en) 2015-02-06 2016-02-05 Compounds and uses in treatment of senescence-associated conditions

Country Status (8)

Country Link
US (2) US20170266211A1 (https=)
EP (1) EP3253387A4 (https=)
JP (1) JP2018508569A (https=)
CN (1) CN108025006A (https=)
AU (1) AU2016215035A1 (https=)
CA (1) CA2981753A1 (https=)
HK (1) HK1249030A1 (https=)
WO (1) WO2016127135A1 (https=)

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US20170216286A1 (en) 2014-01-28 2017-08-03 Mayo Foundation For Medical Education And Research Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoid
TW201613576A (en) 2014-06-26 2016-04-16 Novartis Ag Intermittent dosing of MDM2 inhibitor
MX388093B (es) 2016-11-15 2025-03-19 Novartis Ag Dosis y regimen para inhibidores de la interaccion hdm2-p53.
BR102018007822A2 (pt) 2017-04-20 2018-11-06 Gilead Sciences, Inc. composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
WO2018204830A2 (en) * 2017-05-05 2018-11-08 The Regents Of The University Of California Inhibiting senescent processes in beta cells for the prevention of type 1 diabetes
EP3441069B1 (en) 2017-08-11 2023-04-05 Unity Biotechnology, Inc. Treatment of diabetic retinopathy using pharmaceutical agents that eliminate senescent cells
US20200354336A9 (en) * 2017-08-11 2020-11-12 Unity Biotechnology, Inc. Treatment of Lung Diseases Using Pharmaceutical Agents that Eliminate Senescent Cells
WO2019033122A1 (en) * 2017-08-11 2019-02-14 Unity Biotechnology, Inc. TREATMENT OF PULMONARY DISEASES USING PHARMACEUTICAL AGENTS THAT ELIMINATE SENESCENT CELLS
US10588916B2 (en) 2017-10-31 2020-03-17 Unity Biotechnology, Inc. Technology to inhibit vascular changes that lead to vision loss in the eye
CA3043103C (en) 2017-12-30 2021-02-09 Unity Biotechnology Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer
EP3737681A4 (en) 2018-01-10 2022-01-12 Recurium IP Holdings, LLC BENZAMIDE COMPOUNDS
TWI707849B (zh) 2018-02-13 2020-10-21 美商基利科學股份有限公司 Pd‐1/pd‐l1抑制劑
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JP7080346B2 (ja) * 2018-04-30 2022-06-03 ユニティ バイオテクノロジー インコーポレイテッド 老化細胞によって引き起こされるかまたは媒介される状態の臨床管理における使用のためおよびがんを治療するための、Ｂｃｌファミリーアンタゴニストであるホスホノアミダート
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CA3056878C (en) 2018-04-30 2021-03-30 Unity Biotechnology Phospholidines that are bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
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EP3809983B1 (en) 2018-06-22 2025-08-27 Mayo Foundation for Medical Education and Research Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionality
IL312612A (en) * 2018-07-11 2024-07-01 Rubedo Life Sciences Inc Senolytic compositions and uses thereof
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CN114901594B (zh) * 2019-12-26 2024-09-10 东丽株式会社 氧化铈的纳米粒子、分散体、氧化剂、抗氧化剂及氧化铈的纳米粒子的制造方法
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